Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Bartira Rossi-Bergmann"'
Autor:
Beatriz L.S. Costa Souza, Eduardo F. Pinto, Izabella P.S. Bezerra, Daniel C.O. Gomes, Ana Maria B. Martinez, Maria Inês Ré, Herbert L. de Matos Guedes, Bartira Rossi-Bergmann
Publikováno v:
Vaccine: X, Vol 15, Iss , Pp 100403- (2023)
Intranasal (i.n.) vaccination with adjuvant-free plasmid DNA encoding the leishmanial antigen LACK (LACK DNA) has shown to induce protective immunity against both cutaneous and visceral leishmaniasis in rodents. In the present work, we sought to eval
Externí odkaz:
https://doaj.org/article/1012c43ae1694fbebb4ab8d74a1ea944
Autor:
Letícia Paula Trajano Noronha, Monique Daiane Andrade Martins, Archimedes Barbosa Castro-Junior, Maria Luiza Thorstenberg, Laís Costa-Soares, Thuany Prado Rangel, Felipe Carvalho-Gondim, Bartira Rossi-Bergmann, Luiz Eduardo Baggio Savio, Claudio de Azevedo Canetti, Robson Coutinho-Silva
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Leishmaniasis is a neglected tropical parasitic disease with few approved medications. Cutaneous leishmaniasis (CL) is the most frequent form, responsible for 0.7 - 1.0 million new cases annually worldwide. Leukotrienes are lipid mediators of inflamm
Externí odkaz:
https://doaj.org/article/6041c84d1a4d4ca18d9a2ecd80d0ed74
Autor:
Sarfaraz Ahmad Ejazi, Samiran Saha, Anirban Bhattacharyya, Sonali Das, Nathália Lopes Fontoura Mateus, Manoel Sebastião da Costa Lima, Herintha Coeto Neitzke-Abreu, Ivete Lopes de Mendonca, Carlos Henrique Nery Costa, Otoni Alves de Oliveira Melo, Marcia Almeida de Melo, Bartira Rossi-Bergmann, Raffaele Corso, Laura Manna, Nahid Ali
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Canine visceral leishmaniasis (CVL) due to Leishmania infantum infection is a zoonotic disease prevalent in the areas of South America and the Mediterranean. Infected dogs as reservoirs can contribute to disease transmission and can be a scourge to p
Externí odkaz:
https://doaj.org/article/ed9b2ca292b1462ca05c020142ef353f
Autor:
Júlio Souza dos-Santos, Luan Firmino-Cruz, Alessandra Marcia da Fonseca-Martins, Diogo Oliveira-Maciel, Gustavo Guadagnini Perez, Victor A. Roncaglia-Pereira, Carlos H. Dumard, Francisca H. Guedes-da-Silva, Ana C. Vicente Santos, Monique dos Santos Leandro, Jesuino Rafael Machado Ferreira, Kamila Guimarães-Pinto, Luciana Conde, Danielle A. S. Rodrigues, Marcus Vinicius de Mattos Silva, Renata G. F. Alvim, Tulio M. Lima, Federico F. Marsili, Daniel P. B. Abreu, Orlando C. Ferreira Jr., Ronaldo da Silva Mohana Borges, Amilcar Tanuri, Thiago Moreno L. Souza, Bartira Rossi-Bergmann, André M. Vale, Jerson Lima Silva, Andréa Cheble de Oliveira, Alessandra D’Almeida Filardy, Andre M. O. Gomes, Herbert Leonel de Matos Guedes
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The SARS-CoV-2 pandemic has had a social and economic impact worldwide, and vaccination is an efficient strategy for diminishing those damages. New adjuvant formulations are required for the high vaccine demands, especially adjuvant formulations that
Externí odkaz:
https://doaj.org/article/d7351cdcf7ad400ca37a6f6c36710762
Autor:
Ariane S. Batista, Suellen D.S. Oliveira, Sébastien Pomel, Pierre-Henri Commere, Valérie Mazan, Moses Lee, Philippe M. Loiseau, Bartira Rossi-Bergmann, Eric Prina, Romain Duval
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 149, Iss , Pp 112784- (2022)
Chalcones (1,3-diphenyl-2-propen-1-ones) either natural or synthetic have a plethora of biological properties including antileishmanial activities, but their development as drugs is hampered by their largely unknown mechanisms of action. We demonstra
Externí odkaz:
https://doaj.org/article/31749429bc8d45dba387f0b272d34398
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 11, Iss , Pp 148-155 (2019)
The development of an effective amphotericin B (AmB) topical formulation to replace the systemically toxic injections currently used in cutaneous leishmaniasis (CL) treatment is challenging due to poor absorption through the skin. Aiming at an effect
Externí odkaz:
https://doaj.org/article/e43d9fa4ec5c448091d72ba6cff41b29
Autor:
Ariane de J. Sousa-Batista, Natalia Arruda-Costa, Wallace Pacienza-Lima, Felipe Carvalho-Gondim, Rosiane F. Santos, Silvia A. G. Da-Silva, Maria Inês Ré, Bartira Rossi-Bergmann
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 51 (2022)
Current chemotherapy of cutaneous leishmaniasis (CL) is based on repeated systemic or intralesional administration of drugs that often cause severe toxicity. Previously, we demonstrated the therapeutic potential of biodegradable poly(lactic-co-glycol
Externí odkaz:
https://doaj.org/article/64c83a06095b40629526de0285d86ba4
Autor:
Douglas O Escrivani, Rebecca L Charlton, Marjolly B Caruso, Gabriela A Burle-Caldas, Maria Paula G Borsodi, Russolina B Zingali, Natalia Arruda-Costa, Marcos V Palmeira-Mello, Jéssica B de Jesus, Alessandra M T Souza, Bárbara Abrahim-Vieira, Stefanie Freitag-Pohl, Ehmke Pohl, Paul W Denny, Bartira Rossi-Bergmann, Patrick G Steel
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009951 (2021)
With current drug treatments failing due to toxicity, low efficacy and resistance; leishmaniasis is a major global health challenge that desperately needs new validated drug targets. Inspired by activity of the natural chalcone 2',6'-dihydroxy-4'-met
Externí odkaz:
https://doaj.org/article/97dcebeea4914662b9ca60f477d72118
Autor:
Luan Firmino-Cruz, Júlio Souza dos-Santos, Alessandra Marcia da Fonseca-Martins, Diogo Oliveira-Maciel, Gustavo Guadagnini-Perez, Victor A. Roncaglia-Pereira, Carlos H. Dumard, Francisca H. Guedes-da-Silva, Ana C. Vicente Santos, Renata G. F. Alvim, Tulio M. Lima, Federico F. Marsili, Daniel P. B. Abreu, Bartira Rossi-Bergmann, Andre M. Vale, Alessandra D’Almeida Filardy, Jerson Lima Silva, Andrea Cheble de Oliveira, Andre M. O. Gomes, Herbert Leonel de Matos Guedes
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1305 (2022)
Despite the intramuscular route being the most used vaccination strategy against SARS-CoV-2, the intradermal route has been studied around the globe as a strong candidate for immunization against SARS-CoV-2. Adjuvants have shown to be essential vacci
Externí odkaz:
https://doaj.org/article/71003c2cffe142ad96ce5b6c570e969f
Autor:
Diogo Oliveira-Maciel, Júlio Souza dos-Santos, Gabriel Oliveira-Silva, Mirian França de Mello, Alessandra Marcia da Fonseca-Martins, Monique Pacheco Duarte Carneiro, Tadeu Diniz Ramos, Luan Firmino-Cruz, Daniel Claudio Oliveira Gomes, Bartira Rossi-Bergmann, Herbert Leonel de Matos Guedes
Publikováno v:
Microorganisms, Vol 9, Iss 6, p 1272 (2021)
There is so far no vaccine approved for human leishmaniasis, mainly because of the lack of appropriate adjuvants. This study aimed to evaluate in mice the capacity of a mixture of monophosphoryl lipid A (MPLA) and AddaVax® adjuvants in enhancing the
Externí odkaz:
https://doaj.org/article/107c8e7ffa3d405d97e23d291dec8451