Flood Control: How Milk-Derived Extracellular Vesicles Can Help to Improve the Intestinal Barrier Function and Break the Gut–Joint Axis in Rheumatoid Arthritis

Autor: Joyce Aarts, Annemarie Boleij, Bartijn C. H. Pieters, Anouk L. Feitsma, R. J. Joost van Neerven, Jean Paul ten Klooster, Laura M’Rabet, Onno J. Arntz, Marije I. Koenders, Fons A. J. van de Loo

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Many studies provided compelling evidence that extracellular vesicles (EVs) are involved in the regulation of the immune response, acting as both enhancers and dampeners of the immune system, depending on the source and type of vesicle. Research, inc

Externí odkaz: https://doaj.org/article/7206aa4f590f40579215db13f8663deb

Macrophage-Derived Extracellular Vesicles as Carriers of Alarmins and Their Potential Involvement in Bone Homeostasis

Autor: Bartijn C. H. Pieters, Alfredo Cappariello, Martijn H. J. van den Bosch, Peter L. E. M. van Lent, Anna Teti, Fons A. J. van de Loo

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Extracellular vesicles are a heterogeneous group of cell-derived membranous structures, which facilitate intercellular communication. Recent studies have highlighted the importance of extracellular vesicles in bone homeostasis, as mediators of crosst

Externí odkaz: https://doaj.org/article/605f9676c5824d79a8960daa56856dc9

Bovine Milk-Derived Extracellular Vesicles Inhibit Catabolic and Inflammatory Processes in Cartilage from Osteoarthritis Patients

Autor: Bartijn C. H. Pieters, Onno J. Arntz, Joyce Aarts, Anouk L. Feitsma, R. J. Joost Neerven, Peter M. Kraan, Marina C. Oliveira, Fons A. J. Loo

Publikováno v: Molecular Nutrition and Food Research, 66(6)
Molecular Nutrition & Food Research (Formerly Nahrung/Food), 66, 6
Molecular Nutrition & Food Research (Formerly Nahrung/Food), 66
Molecular Nutrition and Food Research 66 (2022) 6

Contains fulltext : 248971.pdf (Publisher’s version ) (Open Access) SCOPE: Data from the Osteoarthritis Initiative shows that females who drink milk regularly have less joint cartilage loss and OA progression, but the biologic mechanism is unclear.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b19262f52c06dae6d4a66eb5c21d2a
https://doi.org/10.1002/mnfr.202100764

An optimized method for plasma extracellular vesicles isolation to exclude the copresence of biological drugs and plasma proteins which impairs their biological characterization

Autor: Bartijn C. H. Pieters, Fons A. J. van de Loo, Peter L E M van Lent, Marije I. Koenders, Peter M. van der Kraan, Onno J. Arntz

Publikováno v: PLoS One, 15, 7
PLoS One, 15
PLoS ONE, Vol 15, Iss 7, p e0236508 (2020)
PLoS ONE

Extracellular vesicles (EVs) are cell membrane-derived phospholipid bilayer nanostructures that contain bioactive proteins, enzymes, lipids and polymers of nucleotides. They play a role in intercellular communication and are present in body fluids. E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857f8aa19b0ccee6ea69519918535449
https://hdl.handle.net/2066/221425

Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-beta

Autor: Miranda B. Bennink, Peter M. van der Kraan, Marije I. Koenders, Wim B. van den Berg, Mathijs G A Broeren, Peter L E M van Lent, Arjan P. M. van Caam, Bartijn C. H. Pieters, Fons A. J. van de Loo, Onno J. Arntz, Marieke de Vries

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0121123 (2015)
PLoS One, 10
PLoS One, 10, 3

Contains fulltext : 154821.PDF (Publisher’s version ) (Open Access) SCOPE: Extracellular vesicles, including exosomes, have been identified in all biological fluids and rediscovered as an important part of the intercellular communication. Breast mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1c3cbc7677b56154da33b495fd02ff
https://doi.org/10.1371/journal.pone.0121123