Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bartholomew Starich"'
Autor:
Huilin Yang, Michelle N. Karl, Wentao Wang, Bartholomew Starich, Haotian Tan, Ashley Kiemen, Alexandra B. Pucsek, Yun-Huai Kuo, Gabriella C. Russo, Tim Pan, Elizabeth M. Jaffee, Elana J. Fertig, Denis Wirtz, Jamie B. Spangler
Publikováno v:
Molecular Therapy. 30:3430-3449
Simultaneous inhibition of interleukin-6 (IL-6) and interleukin-8 (IL-8) signaling diminishes cancer cell migration, and combination therapy has recently been shown to synergistically reduce metastatic burden in a preclinical model of triple-negative
Autor:
Ivie Aifuwa, Byoung Choul Kim, Pratik Kamat, Bartholomew Starich, Anshika Agrawal, Derin Tanrioven, Teresa R Luperchio, Angela M Jimenez Valencia, Tania Perestrelo, Karen Reddy, Taekjip Ha, Jude M Philip
Publikováno v:
PNAS Nexus. 2
The presence of senescent cells within tissues has been functionally linked to malignant transformations. Here, using tension-gauge tethers technology, particle-tracking microrheology, and quantitative microscopy, we demonstrate that senescent-associ
Autor:
Debonil Maity, Pratik Kamat, Nahuel Zamponi, Hasini Jayatilaka, Anjil Giri, Wenxuan Du, Adrian Johnston, Bartholomew Starich, Michelle Karl, Anshika Agrawal, Deanna Riley, Leandro Venturutti, Ari Melnick, Leandro Cerchietti, Jeremy Walston, Jude M. Phillip
Cell motility is essential to many biological processes as cells navigate and interact within their local microenvironments. Currently, most methods to quantify cell motility rely on the ability to follow and track individual cells. However, results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d772cf54484cc64582520854dfd290b
https://doi.org/10.1101/2022.09.21.508955
https://doi.org/10.1101/2022.09.21.508955
Publikováno v:
Nat Immunol
Extracellular vesicles have emerged as prominent regulators of the immune response during tumor progression. EVs contain a diverse repertoire of molecular cargo that plays a critical role in immunomodulation. Here, we identify the role of EVs as medi
Autor:
Gabriella C. Russo, Ashleigh J. Crawford, David Clark, Julie Cui, Ryan Carney, Michelle N. Karl, Boyang Su, Bartholomew Starich, Tung-Shing Lih, Pratik Kamat, Qiming Zhang, Pei-Hsun Wu, Meng-Horng Lee, Hon S. Leong, Vito W. Rebecca, Hui Zhang, Denis Wirtz
The loss of the intercellular adhesion molecule E-cadherin is a hallmark of the epithelial-mesenchymal transition (EMT), which promotes a transition of cancer cells to a migratory and invasive phenotype. E-cadherin is associated with a decrease in ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfae99d765df92f2ee9c044781fa11a1
https://doi.org/10.1101/2020.11.04.368746
https://doi.org/10.1101/2020.11.04.368746
Publikováno v:
Cancer Research. 79:B28-B28
Pancreatic cancer is the 4th most common cause of cancer-related deaths in the United States, with only a 7-9% 5-year survival rate. While there are a few combination treatments that have been shown to increase overall survival by several months, gem
Autor:
Hava Gil-Henn, Denis Wirtz, Jerry S.H. Lee, Shyam B. Khatau, Gabriella Russo, Fatima G. Umanzor, Hasini Jayatilaka, Bartholomew Starich, Tomer Meirson, Vishwesh Shah, Pranay Tyle
Publikováno v:
Oncotarget
Matrix metalloproteinases (MMPs) may play a critical role in metastatic cancers, yet multiple human clinical trials targeting MMPs have surprisingly failed. Cancer cell density changes dramatically during the early growth of a primary tumor and durin