Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Barthelemy, Diouf"'
Autor:
Barthelemy Diouf, Claudia Wing, John C. Panetta, Donnie Eddins, Wenwei Lin, Wenjian Yang, Yiping Fan, Deqing Pei, Cheng Cheng, Shannon M. Delaney, Wei Zhang, Erik J. Bonten, Kristine R. Crews, Steven W. Paugh, Lie Li, Burgess B. Freeman 3rd, Robert J. Autry, Jordan A. Beard, Daniel C. Ferguson, Laura J. Janke, Kirsten K. Ness, Taosheng Chen, Stanislav S. Zakharenko, Sima Jeha, Ching‐Hon Pui, Mary V. Relling, M. Eileen Dolan, William E. Evans
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 4, Pp 1490-1504 (2021)
Abstract Vincristine (VCR) is one of the most widely prescribed medications for treating solid tumors and acute lymphoblastic leukemia (ALL) in children and adults. However, its major dose‐limiting toxicity is peripheral neuropathy that can disrupt
Externí odkaz:
https://doaj.org/article/e3e40089bb0343279b5f3003e28e87aa
Autor:
Chelsea G. Goodenough, Barthelemy Diouf, Wenjian Yang, Yadav Sapkota, Emily R. Finch, Lu Lu, Robyn E. Partin, Matthew D. Wogksch, Melissa M. Hudson, Leslie L. Robison, Zhaoming Wang, Sima Jeha, William E. Evans, Kirsten K. Ness
Publikováno v:
Leukemia. 36:1160-1163
Autor:
Yiping Fan, William E. Evans, Cheng Cheng, Taosheng Chen, Wenwei Lin, Stanislav S. Zakharenko, Lie Li, Jordan A. Beard, M. Eileen Dolan, Deqing Pei, Kirsten K. Ness, Laura J. Janke, John C. Panetta, Mary V. Relling, Claudia Wing, Sima Jeha, Donnie Eddins, Barthelemy Diouf, Daniel C. Ferguson, Robert J Autry, Erik J. Bonten, Wei Zhang, Wenjian Yang, Shannon M. Delaney, Burgess B. Freeman, Ching-Hon Pui, Steven W. Paugh, Kristine R. Crews
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 4, Pp 1490-1504 (2021)
Clinical and Translational Science, Vol 14, Iss 4, Pp 1490-1504 (2021)
Vincristine is one of the most widely prescribed medications for treating solid tumors and acute lymphoblastic leukemia (ALL) in children and adults. However, its major dose-limiting toxicity is peripheral neuropathy that can disrupt curative therapy
Autor:
Chelsea G, Goodenough, Barthelemy, Diouf, Wenjian, Yang, Yadav, Sapkota, Emily R, Finch, Lu, Lu, Robyn E, Partin, Matthew D, Wogksch, Melissa M, Hudson, Leslie L, Robison, Zhaoming, Wang, Sima, Jeha, William E, Evans, Kirsten K, Ness
Publikováno v:
Leukemia. 36(4)
Autor:
Rikeenkumar Dhaduk, Barthelemy Diouf, Deo Kumar Srivastava, Raja B. Khan, Kari L. Bjornard, Samah Hayek, Yadav Sapkota, William E. Evans, Melissa M. Hudson, Leslie L. Robison, Carmen L. Wilson, Kevin R. Krull, Kirsten K. Ness
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Background: Childhood cancer survivors are at elevated risk for motor and/or sensory neuropathy. The study aims to evaluate the concordance between self-report peripheral neuropathy compared with clinically ascertained peripheral neuropathy, and to i
Autor:
Daniel C. Bowers, Nina S. Kadan-Lottick, M. Eileen Dolan, Kirsten K. Ness, Marilyn J. Hockenberry, Hiroto Inaba, William E. Evans, Kari L. Bjornard, Barthelemy Diouf, Laura Gilchrist, Nicole J. Ullrich
Publikováno v:
The Lancet Child & Adolescent Health. 2:744-754
Peripheral neuropathy is a well-recognized treatment-related toxicity among children with cancer and is associated with exposure to neurotoxic chemotherapy agents. Acute damage, may manifest in sensory, motor, and/or autonomic neurons with symptoms t
Autor:
J. Robert McCorkle, Colton Smith, Kathryn G. Roberts, Steven W. Paugh, John C. Panetta, Deqing Pei, Brandon Smart, Kristine R. Crews, Elixabet Lopez-Lopez, Mary V. Relling, Lei Shi, Barthelemy Diouf, Erik J. Bonten, William E. Evans, Charles G. Mullighan, Ching-Hon Pui, Robert J Autry, Cheng Cheng, Wenjian Yang, Stanley Pounds
Publikováno v:
J Clin Invest
BACKGROUND: Interpatient differences in the accumulation of methotrexate’s active polyglutamylated metabolites (MTXPGs) in leukemia cells influence its antileukemic effects. METHODS: To identify genomic and epigenomic and patient variables determin
Autor:
Barthelemy Diouf, William E. Evans
Publikováno v:
Clinical Pharmacology and Therapeutics
Vincristine is an effective chemotherapeutic drug for various cancers, including acute lymphoblastic leukemia (ALL). Unfortunately, clinical utility is restricted by dose‐limiting vincristine‐induced peripheral neuropathies (VIPN). We sought to d
Autor:
Barthelemy Diouf, Selina M. Luger, Kristina Laumann, Wendy Stock, Richard A. Larson, Kristine R. Crews, Sumithra J. Mandrekar, Richard Stone, Deqing Pei, Cheng Cheng, William E. Evans, Anjali S. Advani
Publikováno v:
Clinical Pharmacology & Therapeutics. 101:391-395
Peripheral neuropathy is a major toxicity of vincristine, yet no strategies exist for identifying adult patients at high-risk. We used a case-control design of 48 adults receiving protocol therapy for acute lymphoblastic leukemia (ALL) who developed
Autor:
Youming Shao, Asli N. Goktug, William E. Evans, Richard J. Heath, Taosheng Chen, Barthelemy Diouf, Ju Bao, Michael Brett Waddell, Anang A. Shelat, Jie Zheng, Mary V. Relling, Wenwei Lin, Christy R. Grace
Publikováno v:
SLAS discovery : advancing life sciences R & D, vol 23, iss 2
Splicing is an important eukaryotic mechanism for expanding the transcriptome and proteome, influencing a number of biological processes. Understanding its regulation and identifying small molecules that modulate this process remain a challenge. We d