The INVENT COVID trial: a structured protocol for a randomized controlled trial investigating the efficacy and safety of intravenous imatinib mesylate (Impentri®) in subjects with acute respiratory distress syndrome induced by COVID-19

Autor: Atmowihardjo, L, Schippers, JR, Bartelink, IH, Bet, PM, van Rein, N, Purdy, K, Cavalla, D, Comberiati, V, McElroy, A, Snape, SD, Bogaard, HJ, Heunks, L, Juffermans, N, Schultz, M, Tuinman, PR, Bos, LDJ, Aman, J

Publikováno v: Trials, 23(1):158. BioMed Central
Atmowihardjo, L, Schippers, J R, Bartelink, I H, Bet, P M, van Rein, N, Purdy, K, Cavalla, D, Comberiati, V, McElroy, A, Snape, S D, Bogaard, H J, Heunks, L, Juffermans, N, Schultz, M, Tuinman, P R, Bos, L D J & Aman, J 2022, ' The INVENT COVID trial : a structured protocol for a randomized controlled trial investigating the efficacy and safety of intravenous imatinib mesylate (Impentri®) in subjects with acute respiratory distress syndrome induced by COVID-19 ', Trials, vol. 23, no. 1, 158 . https://doi.org/10.1186/s13063-022-06055-9
Trials

Background The coronavirus disease 2019 (COVID-19) pandemic has led to a disruptive increase in the number of intensive care unit (ICU) admissions with acute respiratory distress syndrome (ARDS). ARDS is a severe, life-threatening medical condition c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ee7718225d5fd4777c416f9c3ee3c6
https://research.vumc.nl/en/publications/9996d36f-0469-4714-b737-064e40574a78

Guidelines on pediatric dosing on the basis of developmental physiology and harmacokinetic considerations

Autor: Bartelink, IH, Rademaker, CMA, Schobben, AFAM, van den Anker, John

Publikováno v: Clinical Pharmacokinetics, 45, 1077-1097. Adis International Ltd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::ffb02f549d69f8a6c55829b6b88751dc
https://pure.eur.nl/en/publications/58d399da-f90e-4a0b-bfb2-01c03236d272

Body weight-dependent pharmacokinetics of busulfan in paediatric haematopoietic stem cell transplantation patients: towards individualized dosing.

Autor: Bartelink IH, Boelens JJ, Bredius RG, Egberts AC, Wang C, Bierings MB, Shaw PJ, Nath CE, Hempel G, Zwaveling J, Danhof M, Knibbe CA, Bartelink, Imke H, Boelens, Jaap J, Bredius, Robbert G M, Egberts, Antoine C G, Wang, Chenguang, Bierings, Marc B, Shaw, Peter J, Nath, Christa E

Publikováno v: Clinical Pharmacokinetics; 2012, Vol. 51 Issue 5, p331-345, 15p

Genetic Determinants of Busulfan Clearance and Outcomes in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation- Result of a Multicentric Prospective Study on Behalf of the Pediatric Disease Working Party of the European Blood and Marrow Transplantation Group

Autor: Ansari, Marc, Rezgui, M A, Uppugunduri, Chakradhara Rao S, Théoret, Yves, Chalandon, Yves, Dupuis, LL, Schechter, Tal, Bartelink, IH, Boelens, Jaap Jan, Dalle, Jean-Hugues, Azarnoush, Saba, Sedlacek, Petr, Lewis, Victor A., Mezziani, S, Vachon, M-F, Duval, Michel, Champagne, Martin A., Peters, Christina, Bittencourt, Henrique, Krajinovic, Maja

Publikováno v: Blood; December 2014, Vol. 124 Issue: 21 p424-424, 1p

Association of busulfan exposure and outcomes after HCT for patients with an inborn error of immunity.

Autor: Bognàr T; Department of Clinical Pharmacy, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, The Netherlands., Garcia-Rosa M; Transplantation and Cellular Therapies, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY., Lalmohamed A; Department of Clinical Pharmacy, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, The Netherlands.; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Güngör T; Division of Stem Cell Transplantation and Children's Research Center, University Children's Hospital Zürich, University of Zürich, Zürich, Switzerland., Hauri-Hohl M; Division of Stem Cell Transplantation and Children's Research Center, University Children's Hospital Zürich, University of Zürich, Zürich, Switzerland., Prockop S; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA., Oram L; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA., Pai SY; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA.; Center for Cancer Research, National Cancer Institute, National Institutes of Health., Brooks J; Division of Allergy, Immunology, and Bone Marrow Transplantation, Department of Clinical Pharmacy and Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA., Savic RM; Division of Allergy, Immunology, and Bone Marrow Transplantation, Department of Clinical Pharmacy and Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA., Dvorak CC; Division of Allergy, Immunology, and Bone Marrow Transplantation, Department of Clinical Pharmacy and Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA., Long-Boyle JR; Division of Allergy, Immunology, and Bone Marrow Transplantation, Department of Clinical Pharmacy and Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA., Krajinovic M; Centre de Cancérologie Charles-Bruneau, Centre de recherche, Hospital Sainte-Justine Montréal, Montréal, QC, Canada., Bittencourt H; Centre de Cancérologie Charles-Bruneau, Centre de recherche, Hospital Sainte-Justine Montréal, Montréal, QC, Canada., Teyssier AC; Centre de Cancérologie Charles-Bruneau, Centre de recherche, Hospital Sainte-Justine Montréal, Montréal, QC, Canada., Théorêt Y; Centre de Cancérologie Charles-Bruneau, Centre de recherche, Hospital Sainte-Justine Montréal, Montréal, QC, Canada., Martinez C; Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, Houston, TX., Egberts TCG; Department of Clinical Pharmacy, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, The Netherlands.; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Morales E; Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, Houston, TX., Slatter M; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom., Cuvelier GDE; Pediatric Blood and Marrow Transplantation, CancerCare Manitoba, University of Manitoba, Winnipeg, MB, Canada., Chiesa R; Great Ormond Street Hospital for Children & Stem Cell Program, London, United Kingdom., Wynn RF; Department of Blood and Marrow Transplant, Royal Manchester Children's Hospital, Manchester, United Kingdom., Coussons M; Department of Blood and Marrow Transplant, Royal Manchester Children's Hospital, Manchester, United Kingdom., Cicalese MP; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Faculty of Medicine and Surgery, Vita-Salute S. Raffaele University, Milan, Italy.; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Ansari M; Cansearch Research Platform in Pediatric Oncology and Hematology, Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, University of Geneva, Geneva, Switzerland.; Division of Pediatric Oncology and Hematology, Department of Women, Child and Adolescent, University Geneva Hospitals, Geneva, Switzerland., Long SE; Division of Pediatric Blood and Marrow Transplant & Cellular Therapy, M Health Fairview Masonic Children's Hospital, University of Minnesota, Minneapolis, MN., Ebens CL; Division of Pediatric Blood and Marrow Transplant & Cellular Therapy, M Health Fairview Masonic Children's Hospital, University of Minnesota, Minneapolis, MN., Lust H; Stem Cell Transplant Program, Ann & Robert Lurie Children's Hospital, Northwestern University, Chicago, IL., Chaudhury S; Stem Cell Transplant Program, Ann & Robert Lurie Children's Hospital, Northwestern University, Chicago, IL., Nath CE; Children's Hospital at Westmead, Sydney, Australia., Shaw PJ; Children's Hospital at Westmead, Sydney, Australia., Keogh SJ; Children's Hospital at Westmead, Sydney, Australia., van der Stoep MYEC; Department of Pediatrics, Willem Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands.; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.; Center for Cell and Gene Therapy, Leiden University Medical Center, Leiden, The Netherlands., Bredius R; Department of Pediatrics, Willem Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands., Lindemans CA; Department of Pediatrics, University Medical Center Utrecht, Utrecht, The Netherlands.; Princess Máxima Center Utrecht, Utrecht, The Netherlands., Boelens JJ; Transplantation and Cellular Therapies, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY., Bartelink IH; Amsterdam University Medical Center, Location VUmc, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Imaging and Biomarkers, Amsterdam, The Netherlands.

Publikováno v: Blood advances [Blood Adv] 2024 Oct 08; Vol. 8 (19), pp. 5137-5145.