Zobrazeno 1 - 10
of 335
pro vyhledávání: '"Bart-Jan Kullberg"'
Autor:
Javier Botey-Bataller, Hedwig D. Vrijmoeth, Jeanine Ursinus, Bart-Jan Kullberg, Cees C. van den Wijngaard, Hadewych ter Hofstede, Ahmed Alaswad, Manoj K. Gupta, Lennart M. Roesner, Jochen Huehn, Thomas Werfel, Thomas F. Schulz, Cheng-Jian Xu, Mihai G. Netea, Joppe W. Hovius, Leo A. B. Joosten, Yang Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The incidence of Lyme borreliosis has risen, accompanied by persistent symptoms. The innate immune system and related cytokines are crucial in the host response and symptom development. We characterized cytokine production capacity before an
Externí odkaz:
https://doaj.org/article/e3dcc9f358504f8d8994380adb860b5e
Autor:
Foekje F. Stelma, Anneleen Berende, Hadewych Ter Hofstede, Hedwig D. Vrijmoeth, Fidel Vos, Bart-Jan Kullberg
Publikováno v:
Life, Vol 13, Iss 5, p 1134 (2023)
Objective: The diagnosis of Lyme borreliosis is based on two-tier testing using an ELISA and Western blot. About 5–10% of patients report persistent symptoms of unknown etiology after treatment, resulting in substantial difficulties in further diag
Externí odkaz:
https://doaj.org/article/b15388c1ee9549f29949753e3df15756
Autor:
Hedwig D. Vrijmoeth, Jeanine Ursinus, Margriet G. Harms, Tizza P. Zomer, Stefanie A. Gauw, Anna D. Tulen, Kristin Kremer, Hein Sprong, Hans Knoop, Yolande M. Vermeeren, Barend van Kooten, Leo A. B. Joosten, Bart-Jan Kullberg, Joppe W. R. Hovius, Cees C. van den Wijngaard
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background After antibiotic treatment of Lyme borreliosis, a subset of patients report persistent symptoms, also referred to as post-treatment Lyme disease syndrome. The reported prevalence of persistent symptoms varies considerably, and its
Externí odkaz:
https://doaj.org/article/e3e96edd91884fe4877425766b36d429
Autor:
Marvin AH Berrevoets, Jaap ten Oever, Tom Sprong, Reinier M van Hest, Ingeborg Groothuis, Inger van Heijl, Jeroen A Schouten, Marlies E Hulscher, Bart-Jan Kullberg
Publikováno v:
BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background The Dutch Working Party on Antibiotic Policy is developing a national antimicrobial stewardship registry. This registry will report both the quality of antibiotic use in hospitals in the Netherlands and the stewardship activities
Externí odkaz:
https://doaj.org/article/1182089ac43c49d38b80998112f465d6
Autor:
Marvin A. H. Berrevoets, Johannes (Hans) L. W. Pot, Anne E. Houterman, Anton (Ton) S. M. Dofferhoff, Marrigje H. Nabuurs-Franssen, Hanneke W. H. A. Fleuren, Bart-Jan Kullberg, Jeroen A. Schouten, Tom Sprong
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 6, Iss 1, Pp 1-8 (2017)
Abstract Background Timely switch from intravenous (iv) antibiotics to oral therapy is a key component of antimicrobial stewardship programs in order to improve patient safety, promote early discharge and reduce costs. We have introduced a time-effic
Externí odkaz:
https://doaj.org/article/434ce831fb7446ab98ae4d321b1002eb
Autor:
Gerben Ferwerda, Stephen E Girardin, Bart-Jan Kullberg, Lionel Le Bourhis, Dirk J de Jong, Dennis M L Langenberg, Reinout van Crevel, Gosse J Adema, Tom H M Ottenhoff, Jos W M Van der Meer, Mihai G Netea
Publikováno v:
PLoS Pathogens, Vol 1, Iss 3, Pp 279-285 (2005)
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and adaptive immune responses. In the present study, w
Externí odkaz:
https://doaj.org/article/6488f73434ec4f34b39dffefb812df9c
Autor:
Tania O Crişan, Theo S Plantinga, Frank L van de Veerdonk, Marius F Farcaş, Monique Stoffels, Bart-Jan Kullberg, Jos W M van der Meer, Leo A B Joosten, Mihai G Netea
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18666 (2011)
Autophagy is a cell housekeeping mechanism that has recently received attention in relation to its effects on the immune response. Genetic studies have identified candidate loci for Crohn's disease susceptibility among autophagy genes, while experime
Externí odkaz:
https://doaj.org/article/fbf50f8105a14cbabda36fb413ff6dd1
Autor:
Marije Oosting, Hadewych Ter Hofstede, Patrick Sturm, Gosse J Adema, Bart-Jan Kullberg, Jos W M van der Meer, Mihai G Netea, Leo A B Joosten
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25998 (2011)
After infection with Borrelia species, the risk for developing Lyme disease varies significantly between individuals. Recognition of Borrelia by the immune system is mediated by pattern recognition receptors (PRRs), such as TLRs. While TLR2 is the ma
Externí odkaz:
https://doaj.org/article/ecc984d867ee40268aed87ef0f194c75
Autor:
Mihai G Netea, Anna Simon, Frank van de Veerdonk, Bart-Jan Kullberg, Jos W M Van der Meer, Leo A B Joosten
Publikováno v:
PLoS Pathogens, Vol 6, Iss 2, p e1000661 (2010)
Stimulation and release of proinflammatory cytokines is an essential step for the activation of an effective innate host defense, and subsequently for the modulation of adaptive immune responses. Interleukin-1beta (IL-1beta) and IL-18 are important p
Externí odkaz:
https://doaj.org/article/33d7bf10366f44d4b9e4ab5a32681e69
Autor:
M E Baarsma, Freek R van de Schoor, Stefanie A Gauw, Hedwig D Vrijmoeth, Jeanine Ursinus, Nienke Goudriaan, Calin D Popa, Hadewych JM ter Hofstede, Mariska MG Leeflang, Kristin Kremer, Cees C van den Wijngaard, Bart-Jan Kullberg, Leo AB Joosten, Joppe W Hovius
Publikováno v:
Lancet Infectious Diseases, 22, 1388-1396
The Lancet Infectious Diseases, 22(9), 1388-1396. Lancet Publishing Group
Lancet Infectious Diseases, 22, 9, pp. 1388-1396
The Lancet Infectious Diseases, 22(9), 1388-1396. Lancet Publishing Group
Lancet Infectious Diseases, 22, 9, pp. 1388-1396
Contains fulltext : 286839.pdf (Publisher’s version ) (Closed access) BACKGROUND: Cellular tests for Lyme borreliosis might be able to overcome major shortcomings of serological testing, such as its low sensitivity in early stages of infection. The