Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bart van den Hazel"'
Publikováno v:
Journal of Biological Chemistry. 271:11865-11870
The sorting of the yeast proteases proteinase A and carboxypeptidase Y to the vacuole is a saturable, receptor-mediated process. Information sufficient for vacuolar sorting of the normally secreted protein invertase has in fusion constructs previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e5542f604fa6f2fa8e2fefb98d903f
https://doi.org/10.1074/jbc.271.20.11865
https://doi.org/10.1074/jbc.271.20.11865
Publikováno v:
Yeast. 12:1-16
The yeast vacuole, which is equivalent to the lysosome of higher eukaryotes, is one of the best characterized degradative organelles. This review describes the biosynthesis and function of yeast vacuolar proteases. Most of these enzymes are delivered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e17a6eef3591a84f4568811fb8484906
https://doi.org/10.1002/(sici)1097-0061(199601)12:1<1::aid-yea902>3.0.co
https://doi.org/10.1002/(sici)1097-0061(199601)12:1<1::aid-yea902>3.0.co
Publikováno v:
Journal of Biological Chemistry. 270:8602-8609
The yeast aspartic protease, proteinase A, has a 54 amino-acid propeptide, which is removed during activation of the zymogen in the vacuole. Apart from being involved inhibition/activation, the propeptide has been shown to be essential for formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd0e0abf8fbc13cab8c07dbe820fdb2
https://doi.org/10.1074/jbc.270.15.8602
https://doi.org/10.1074/jbc.270.15.8602
Publikováno v:
European Journal of Biochemistry. 220:19-27
Carboxypeptidase Y is a vacuolar enzyme from Saccharomyces cerevisiae. It enters the vacuole as a zymogen, procarboxypeptidase Y, which is immediately processed in a reaction involving two endoproteases, proteinase A and proteinase B. We have investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baae5d4ee02982a94bb4643c8fc54be
https://doi.org/10.1111/j.1432-1033.1994.tb18594.x
https://doi.org/10.1111/j.1432-1033.1994.tb18594.x
Publikováno v:
European Journal of Biochemistry. 207:277-283
The Saccharomyces cerevisiae PEP4 gene encodes proteinase A, an aspartyl protease. pep4 mutants are defective in the activation of many vacuolar hydrolases, including proteinase B. We have expressed a pep4 mutation which directs the accumulation of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0452696eb93e6e3335417fb6d282b05b
https://doi.org/10.1111/j.1432-1033.1992.tb17048.x
https://doi.org/10.1111/j.1432-1033.1992.tb17048.x
Autor:
Jesper Christiansen, Kim Vilbour Andersen, Hans Thalsgaard Schambye, Signe Perlman, Torben Halkier, Sigurd Okkels, Bart Van Den Hazel, Sanne Gram-Nielsen, Claus Bekker Jeppesen
Publikováno v:
The Journal of clinical endocrinology and metabolism. 88(7)
FSH is a key component in assisted reproductive technologies. Because of rapid clearance of the hormone, patients have to be treated with daily injections. To address this problem, a long-acting FSH mutein was created by introduction of additional N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e35292258a3df74bcc66ab3327b422
https://pubmed.ncbi.nlm.nih.gov/12843169
https://pubmed.ncbi.nlm.nih.gov/12843169
Autor:
Maria Adelaide do Valle Matta, Jean-Luc Jonniaux, André Goffeau, Bart van den Hazel, Elisabetta Balzi
Publikováno v:
Gene. 272(1-2)
The yeast transcription factor Pdr1p regulates the expression of a number of genes, several of which encode ATP-driven transport proteins involved in multiple drug resistance. Among 20 genes containing binding consensus sequences for the transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af87fac0eb8c67f994786cfde7100cd6
https://pubmed.ncbi.nlm.nih.gov/11470516
https://pubmed.ncbi.nlm.nih.gov/11470516
Autor:
Claude Jacq, Bart van den Hazel, Elisabetta Balzi, André Goffeau, Joseph L. DeRisi, Patrick O. Brown, Philippe Marc
Publikováno v:
FEBS letters. 470(2)
The cDNA from activated mutants of the homologous transcription factors Pdr1p and Pdr3p was used to screen DNA microarrays of the Saccharomyces cerevisiae complete genome. Twenty-six overexpressed targets of the PDR1-3 and/or PDR3-7 mutants were iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121ded8c466e6dca69eff582245485e9
https://pubmed.ncbi.nlm.nih.gov/10734226
https://pubmed.ncbi.nlm.nih.gov/10734226
Autor:
Harald Pichler, Hans Bart Van den Hazel, Maria Adelaide Do Valle Matta, Andre Goffeau, Günther Daum
Publikováno v:
TU Graz
Harald Pichler
Harald Pichler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::196bfce5090d57e109ff6f0849cc49d9
https://pure.tugraz.at/portal/en/publications/drug-sensitivity-and-lipid-composition-of-the-plasma-membrane-are-affected-by-deletion-of-two-yeast-sec14-homologues(5a4d3b71-e189-4d7c-9df9-69ecd13af0a9).html
https://pure.tugraz.at/portal/en/publications/drug-sensitivity-and-lipid-composition-of-the-plasma-membrane-are-affected-by-deletion-of-two-yeast-sec14-homologues(5a4d3b71-e189-4d7c-9df9-69ecd13af0a9).html
