Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Bart N M, van Berckel"'
Autor:
Hayel Tuncel, Denise Visser, Tessa Timmers, Emma E. Wolters, Rik Ossenkoppele, Wiesje M. van der Flier, Bart N. M. van Berckel, Ronald Boellaard, Sandeep S. V. Golla
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Background Dynamic PET imaging studies provide accurate estimates of specific binding, but also measure the relative tracer delivery (R1), which is a proxy for relative cerebral blood flow (rCBF). Recently, studies suggested that R1 obtained
Externí odkaz:
https://doaj.org/article/5b92fa28a272466696c487ff5bf1f7c8
Autor:
Marie-Paule E. van Engelen, Sander C. J. Verfaillie, Annemieke Dols, Mardien L. Oudega, Ronald Boellaard, Sandeep S. V. Golla, Marijke den Hollander, Rik Ossenkoppele, Philip Scheltens, Bart N. M. van Berckel, Yolande A. L. Pijnenburg, Everard G. B. Vijverberg
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Background Behavioural symptoms and frontotemporal hypometabolism overlap between behavioural variant of frontotemporal dementia (bvFTD) and primary psychiatric disorders (PPD), hampering diagnostic distinction. Voxel-wise comparisons of bra
Externí odkaz:
https://doaj.org/article/2e33ccec1e054043a8dbf5dff021fd33
Autor:
Anna Brugulat-Serrat, Gonzalo Sánchez-Benavides, Raffaele Cacciaglia, Gemma Salvadó, Mahnaz Shekari, Lyduine E. Collij, Christopher Buckley, Bart N. M. van Berckel, Andrés Perissinotti, Aida Niñerola-Baizán, Marta Milà-Alomà, Natàlia Vilor-Tejedor, Grégory Operto, Carles Falcon, Oriol Grau-Rivera, Eider M. Arenaza-Urquijo, Carolina Minguillón, Karine Fauria, José Luis Molinuevo, Marc Suárez-Calvet, Juan Domingo Gispert, the ALFA Study
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Purpose To determine whether the APOE-ε4 allele modulates the relationship between regional β-amyloid (Aβ) accumulation and cognitive change in middle-aged cognitively unimpaired (CU) participants. Methods The 352 CU participants (mean ag
Externí odkaz:
https://doaj.org/article/0d4f03806f1d42348aadd1865d2552d8
Autor:
Amira Soliman, Jose R. Chang, Kobra Etminani, Stefan Byttner, Anette Davidsson, Begoña Martínez-Sanchis, Valle Camacho, Matteo Bauckneht, Roxana Stegeran, Marcus Ressner, Marc Agudelo-Cifuentes, Andrea Chincarini, Matthias Brendel, Axel Rominger, Rose Bruffaerts, Rik Vandenberghe, Milica G. Kramberger, Maja Trost, Nicolas Nicastro, Giovanni B. Frisoni, Afina W. Lemstra, Bart N. M. van Berckel, Andrea Pilotto, Alessandro Padovani, Silvia Morbelli, Dag Aarsland, Flavio Nobili, Valentina Garibotto, the Alzheimer’s Disease Neuroimaging Initiative, Miguel Ochoa-Figueroa
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 22, Iss S6, Pp 1-15 (2022)
Abstract Background In recent years, neuroimaging with deep learning (DL) algorithms have made remarkable advances in the diagnosis of neurodegenerative disorders. However, applying DL in different medical domains is usually challenged by lack of lab
Externí odkaz:
https://doaj.org/article/1e31be5db89c45979ee82efd965f3f6d
Autor:
Arenda Mank, Judith J. M. Rijnhart, Ingrid S. van Maurik, Linus Jönsson, Ron Handels, Els D. Bakker, Charlotte E. Teunissen, Bart N. M. van Berckel, Argonde C. van Harten, Johannes Berkhof, Wiesje M. van der Flier
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Background Quality of life (QoL) is an important outcome from the perspective of patients and their caregivers, in both dementia and pre-dementia stages. Yet, little is known about the long-term changes in QoL over time. We aimed to compare
Externí odkaz:
https://doaj.org/article/9ae514995a574a0da9c50b37b218341a
Autor:
Jarith L. Ebenau, Denise Visser, Lior A. Kroeze, Mardou S. S. A. van Leeuwenstijn, Argonde C. van Harten, Albert D. Windhorst, Sandeep V. S. Golla, Ronald Boellaard, Philip Scheltens, Frederik Barkhof, Bart N. M. van Berckel, Wiesje M. van der Flier
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Background Biomarkers for amyloid, tau, and neurodegeneration (ATN) have predictive value for clinical progression, but it is not clear how individuals move through these stages. We examined changes in ATN profiles over time, and investigate
Externí odkaz:
https://doaj.org/article/2a10f0eecc1f491fb787668eb12f36a8
Autor:
Frederik Barkhof, Johanna M A Visser-Meily, Maria Prins, Janneke Horn, Menno D de Jong, Arjen J C Slooter, Caroline M van Heugten, Denise Visser, Michele van Vugt, Hanneke E Hulst, Nelleke Tolboom, Bart N M van Berckel, Dook W Koch, Godelieve de Bree, Cees C van den Wijngaard, Tessa van der Maaden, Anouk Verveen, Sander C J Verfaillie, Irene Csorba, Emma M Coomans, Brent Appelman, Ronald Boellaard, Elsmarieke M van de Giessen, Sandeep Golla, Tanja A Kuut, Yvonne M G van Os, P T Nieuwkerk, H Knoop
Publikováno v:
BMJ Open, Vol 13, Iss 6 (2023)
Introduction The risk factors for persistent fatigue and cognitive complaints after infection with SARS-CoV-2 and the underlying pathophysiology are largely unknown. Both clinical factors and cognitive-behavioural factors have been suggested to play
Externí odkaz:
https://doaj.org/article/e696799c650c4ba8830baf18716f9f63
Autor:
Fiona Heeman, Maqsood Yaqub, Janine Hendriks, Bart N. M. van Berckel, Lyduine E. Collij, Katherine R. Gray, Richard Manber, Robin Wolz, Valentina Garibotto, Catriona Wimberley, Craig Ritchie, Frederik Barkhof, Juan Domingo Gispert, David Vállez García, Isadora Lopes Alves, Adriaan A. Lammertsma, on behalf of the AMYPAD Consortium
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Background Despite its widespread use, the semi-quantitative standardized uptake value ratio (SUVR) may be biased compared with the distribution volume ratio (DVR). This bias may be partially explained by changes in cerebral blood flow (CBF)
Externí odkaz:
https://doaj.org/article/3719a1fba4d443faa2e3f243c084473b
Autor:
Hayel Tuncel, Ronald Boellaard, Emma M. Coomans, Marijke den Hollander-Meeuwsen, Erik F. J. de Vries, Andor W. J. M. Glaudemans, Paula Kopschina Feltes, David Vállez García, Sander C. J. Verfaillie, Emma E. Wolters, Steven P. Sweeney, J. Michael Ryan, Magnus Ivarsson, Berkley A. Lynch, Patrick Schober, Philip Scheltens, Robert C. Schuit, Albert D. Windhorst, Peter P. De Deyn, Bart N. M. van Berckel, Sandeep S. V. Golla
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract [11C]UCB-J is a PET radioligand that binds to the presynaptic vesicle glycoprotein 2A. Therefore, [11C]UCB-J PET may serve as an in vivo marker of synaptic integrity. The main objective of this study was to evaluate the quantitative accuracy
Externí odkaz:
https://doaj.org/article/1d98093e987342dd9416579091feee0d
Autor:
Rosha Babapour Mofrad, Philip Scheltens, SangYun Kim, Sungmin Kang, Young Chul Youn, Seong Soo A. An, Jori Tomassen, Bart N. M. van Berckel, Pieter Jelle Visser, Wiesje M. van der Flier, Charlotte E. Teunissen
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-10 (2021)
Abstract Objective We assessed the performance of plasma amyloid oligomerization tendency (OAβ) as a marker for abnormal amyloid status. Additionally, we examined long-term storage effects on plasma OAβ. Methods We included 399 subjects regardless
Externí odkaz:
https://doaj.org/article/b4d4b0f74e0c405c9f4317733a93b7c0