Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Bart J.M. van Vlijmen"'
Autor:
Noémie Kraaijpoel, Frits I. Mulder, Marc Carrier, Annabel van Lieshout, Tom Würdinger, Myron G. Best, Bart J.M. van Vlijmen, Yassene Mohammed, Luis Jara-Palomares, Pieter W. Kamphuisen, Marcello Di Nisio, Walter Ageno, Jan Beyer-Westendorf, Thomas Vanassche, Frederikus A. Klokm, Hans-Martin Otten, Mike J.L. Peters, Benilde Cosmi, Marije ten Wolde, Patrick M.M. Bossuyt, Harry R. Büller, Nick van Es
Publikováno v:
Thrombosis Update, Vol 2, Iss , Pp 100030- (2021)
Occult cancer is detected in about 5% of patients with unprovoked venous thromboembolism (VTE) in the 12 months following VTE diagnosis. Current guidance suggests conducting a ‘limited’ cancer screening in these patients, consisting of medical hi
Externí odkaz:
https://doaj.org/article/2dd9496a84fc4b7081e92959d00b7e2f
Autor:
Lihui Hu, Caroline C. van der Hoogt, Sonia M.S. Espirito Santo, Ruud Out, Kyriakos E. Kypreos, Bart J.M. van Vlijmen, Theo J.C. Van Berkel, Johannes A. Romijn, Louis M. Havekes, Ko Willems van Dijk, Patrick C.N. Rensen
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 7, Pp 1553-1561 (2008)
LPL activity plays an important role in preceding the VLDL remnant clearance via the three major apolipoprotein E (apoE)-recognizing receptors: the LDL receptor (LDLr), LDL receptor-related protein (LRP), and VLDL receptor (VLDLr). The aim of this st
Externí odkaz:
https://doaj.org/article/a8056d64064e4a8d9eac042aaa09fbbe
Autor:
Sonia M. S. Espirito Santo, Patrick C.N. Rensen, Jeltje R. Goudriaan, André Bensadoun, Niels Bovenschen, Peter J. Voshol, Louis M. Havekes, Bart J.M. van Vlijmen
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 6, Pp 1097-1102 (2005)
The very low density lipoprotein receptor (VLDLR), low density lipoprotein receptor (LDLR), and low density lipoprotein receptor-related protein (LRP) are the three main apolipoprotein E-recognizing endocytic receptors involved in the clearance of tr
Externí odkaz:
https://doaj.org/article/cbe0f4e5aaea4945ba9b2c3b024e89d7
Autor:
Jeltje R. Goudriaan, Sonia M. S. Espirito Santo, Peter J. Voshol, Bas Teusink, Ko Willems van Dijk, Bart J.M. van Vlijmen, Johannes A. Romijn, Louis M. Havekes, Patrick C.N. Rensen
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 8, Pp 1475-1481 (2004)
The VLDL receptor (VLDLr) is involved in tissue delivery of VLDL-triglyceride (TG)-derived FFA by facilitating the expression of lipoprotein lipase (LPL). However, vldlr−/− mice do not show altered plasma lipoprotein levels, despite reduced LPL e
Externí odkaz:
https://doaj.org/article/b75c9e060e0b440fb14d3e777662b8f1
Autor:
Ko Willems van Dijk, Bart J.M. van Vlijmen, H. Belinda van't Hof, Andre van der Zee, Silvia Santamarina-Fojo, Theo J.C. van Berkel, Louis M. Havekes, Marten H. Hofker
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 2, Pp 336-344 (1999)
To investigate the quantitative requirement for apolipoprotein (apo) E in the clearance of lipoproteins via the non-low density lipoprotein (LDL) receptor mediated pathway, human APOE was overexpressed at various levels in the livers of mice deficien
Externí odkaz:
https://doaj.org/article/dacd6fdf7c9f458c817e4f8d13cacdde
Autor:
Bart J.M. van Vlijmen, Ronald P. Mensink, H. Belinda van 't Hof, Rene F.G. Offermans, Marten H. Hofker, Louis M. Havekes
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 6, Pp 1181-1188 (1998)
Studying the effects of dietary fish oil on VLDL metabolism in humans is subject to both large intra- and interindividual variability. In the present study we therefore used hyperlipidemic apolipoprotein (APO) E*3-Leiden mice, which have impaired chy
Externí odkaz:
https://doaj.org/article/9372995dc13348d094312cc9ce94c3d1
Autor:
Alfred H. Schinkel, Jos H. Beijnen, Bart J.M. van Vlijmen, Tsuyoshi Yokoi, Els Wagenaar, Selvi Durmus, Tatsuki Fukami, Ka Lei Cheung, Rolf W. Sparidans, Seng Chuan Tang
PDF file - 110KB, S1. Overview of the corresponding deltaCt values belonging to the RT-PCR results as shown in Supplementary Data 2. S2. Overview of the corresponding ΔCt values belonging to the RT-PCR results as shown in Figure 4. S3. Overview of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8384d7d06ad1ed51601b0184ecf9c414
https://doi.org/10.1158/1078-0432.22452147
https://doi.org/10.1158/1078-0432.22452147
Autor:
Alfred H. Schinkel, Jos H. Beijnen, Bart J.M. van Vlijmen, Tsuyoshi Yokoi, Els Wagenaar, Selvi Durmus, Tatsuki Fukami, Ka Lei Cheung, Rolf W. Sparidans, Seng Chuan Tang
PDF file - 117KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8521c99bbaa4e7418539b2d0498f7cf2
https://doi.org/10.1158/1078-0432.22452150.v1
https://doi.org/10.1158/1078-0432.22452150.v1
Autor:
Alfred H. Schinkel, Jos H. Beijnen, Bart J.M. van Vlijmen, Tsuyoshi Yokoi, Els Wagenaar, Selvi Durmus, Tatsuki Fukami, Ka Lei Cheung, Rolf W. Sparidans, Seng Chuan Tang
PDF file - 666KB, S1. Molecular structure of everolimus (A) and putative molecular structure of metabolite A (B). S2. 2. Liver expression of Ces1 and Ces2 genes in male wild-type, Abcb1a/1b(-/-), Abcg2(-/-) and Abcb1a/1b;Abcg2(-/-) mice. S3. Inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c68caac991e54449bb35751b7738675
https://doi.org/10.1158/1078-0432.22452153.v1
https://doi.org/10.1158/1078-0432.22452153.v1
Autor:
Alfred H. Schinkel, Jos H. Beijnen, Bart J.M. van Vlijmen, Tsuyoshi Yokoi, Els Wagenaar, Selvi Durmus, Tatsuki Fukami, Ka Lei Cheung, Rolf W. Sparidans, Seng Chuan Tang
Purpose: To clarify the role of ABCB1, ABCG2, and CYP3A in blood and brain exposure of everolimus using knockout mouse models.Experimental Design: We used wild-type, Abcb1a/1b−/−, Abcg2−/−, Abcb1a/1b;Abcg2−/−, and Cyp3a−/− mice to stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d60f8a357693a7b2f17b2d095a9749
https://doi.org/10.1158/1078-0432.c.6522396
https://doi.org/10.1158/1078-0432.c.6522396