Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bart J. Brown"'
Autor:
James R. Howe, Thomas M. O'Dorisio, Joseph S. Dillon, Chandrikha Chandrasekharan, Andrew M. Bellizzi, Dawn E. Quelle, Chandra K. Maharjan, Courtney A. Kaemmer, Shaikamjad Umesalma, Guiying Li, Terry A. Braun, Bart J. Brown, Benjamin Darbro, Po Hien Ear, Patrick J. Breheny, Michelle Weitz, Aaron T. Scott
Supplementary table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04208effee2d15d00eea96bc7cc41d0f
https://doi.org/10.1158/1078-0432.22479092
https://doi.org/10.1158/1078-0432.22479092
Autor:
James R. Howe, Thomas M. O'Dorisio, Joseph S. Dillon, Chandrikha Chandrasekharan, Andrew M. Bellizzi, Dawn E. Quelle, Chandra K. Maharjan, Courtney A. Kaemmer, Shaikamjad Umesalma, Guiying Li, Terry A. Braun, Bart J. Brown, Benjamin Darbro, Po Hien Ear, Patrick J. Breheny, Michelle Weitz, Aaron T. Scott
Supplementary table 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939dcad7c58b409c0015525c82f53295
https://doi.org/10.1158/1078-0432.22479086.v1
https://doi.org/10.1158/1078-0432.22479086.v1
Autor:
James R. Howe, Thomas M. O'Dorisio, Joseph S. Dillon, Chandrikha Chandrasekharan, Andrew M. Bellizzi, Dawn E. Quelle, Chandra K. Maharjan, Courtney A. Kaemmer, Shaikamjad Umesalma, Guiying Li, Terry A. Braun, Bart J. Brown, Benjamin Darbro, Po Hien Ear, Patrick J. Breheny, Michelle Weitz, Aaron T. Scott
Supplementary table 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00debd7fae75824de3070d69f5154ec9
https://doi.org/10.1158/1078-0432.22479077
https://doi.org/10.1158/1078-0432.22479077
Autor:
James R. Howe, Thomas M. O'Dorisio, Joseph S. Dillon, Chandrikha Chandrasekharan, Andrew M. Bellizzi, Dawn E. Quelle, Chandra K. Maharjan, Courtney A. Kaemmer, Shaikamjad Umesalma, Guiying Li, Terry A. Braun, Bart J. Brown, Benjamin Darbro, Po Hien Ear, Patrick J. Breheny, Michelle Weitz, Aaron T. Scott
Supplementary table 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0002bdc0091cc20bef21bdd911b62d
https://doi.org/10.1158/1078-0432.22479074.v1
https://doi.org/10.1158/1078-0432.22479074.v1
Autor:
James R. Howe, Thomas M. O'Dorisio, Joseph S. Dillon, Chandrikha Chandrasekharan, Andrew M. Bellizzi, Dawn E. Quelle, Chandra K. Maharjan, Courtney A. Kaemmer, Shaikamjad Umesalma, Guiying Li, Terry A. Braun, Bart J. Brown, Benjamin Darbro, Po Hien Ear, Patrick J. Breheny, Michelle Weitz, Aaron T. Scott
Purpose:Pancreatic neuroendocrine tumors (pNETs) are uncommon malignancies noted for their propensity to metastasize and comparatively favorable prognosis. Although both the treatment options and clinical outcomes have improved in the past decades, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077ed5a829204ec14de74eeb5bd77b88
https://doi.org/10.1158/1078-0432.c.6530126.v1
https://doi.org/10.1158/1078-0432.c.6530126.v1
Autor:
James R. Howe, Thomas M. O'Dorisio, Joseph S. Dillon, Chandrikha Chandrasekharan, Andrew M. Bellizzi, Dawn E. Quelle, Chandra K. Maharjan, Courtney A. Kaemmer, Shaikamjad Umesalma, Guiying Li, Terry A. Braun, Bart J. Brown, Benjamin Darbro, Po Hien Ear, Patrick J. Breheny, Michelle Weitz, Aaron T. Scott
Supplementary table 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874924a278ac507125c53dba50ee99bc
https://doi.org/10.1158/1078-0432.22479083
https://doi.org/10.1158/1078-0432.22479083
RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth
Autor:
Jussara Hagen, Timothy Ginader, Abbey L. Perl, Terry A. Braun, Gideon K. D. Zamba, Bart J. Brown, Dawn E. Quelle, James R. Howe, Jacqueline A. Reilly, Goutham Narla, Benjamin W. Darbro, Fenghuang Zhan, Angela M. Schab, Aaron T. Scott, Blake L. Letney, Jordan L. Kohlmeyer, Courtney A. Kaemmer, Shaikamjad Umesalma, Joseph S. Dillon, David K. Meyerholz, Mariah R. Leidinger, Stefan Strack, Thomas M. O'Dorisio, Andrew M. Bellizzi, Agshin F. Taghiyev, Frederick W. Quelle, Nitija Tiwari, Ronald A. Merrill, Ryan M. Sheehy
Publikováno v:
Journal of Clinical Investigation. 129:1641-1653
Hyperactivated AKT/mTOR signaling is a hallmark of pancreatic neuroendocrine tumors (PNETs). Drugs targeting this pathway are used clinically, but tumor resistance invariably develops. A better understanding of factors regulating AKT/mTOR signaling a