Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Bart J, Verwer"'
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Akademický článek
Plasma Cathepsin D Activity Rather Than Levels Correlates With Metabolic Parameters of Type 2 Diabetes in Male Individuals
Autor: Lingling Ding, Tom Houben, Yvonne Oligschlaeger, Albert V. Bitorina, Bart J. Verwer, Maarten E. Tushuizen, Ronit Shiri-Sverdlov
Publikováno v: Frontiers in Endocrinology, Vol 11 (2020)
ObjectiveType 2 diabetes mellitus is a metabolic disorder characterized by insulin resistance. Previous studies in patients demonstrated that plasma levels of cathepsin D (CTSD), which is optimally active in the acidic environment of lysosomes, corre
Externí odkaz: https://doaj.org/article/76ee5e60d2944982927fd70735b568d1
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NAFLD is related to Post‐prandial Triglyceride‐enrichment of HDL Particles in Association with Endothelial and HDL Dysfunction
Autor: Petra J.W. Pouwels, P. G. Scheffer, Maarten E. Tushuizen, Rick P. Vermue, Bart J. Verwer, M. Diamant
Publikováno v: Liver International, 40(10), 2439-2444. WILEY
Liver International, 40(10), 2439-2444. Wiley-Blackwell
Verwer, B J, Scheffer, P G, Vermue, R P, Pouwels, P J, Diamant, M & Tushuizen, M E 2020, ' NAFLD is related to Post-prandial Triglyceride-enrichment of HDL Particles in Association with Endothelial and HDL Dysfunction ', Liver International, vol. 40, no. 10, pp. 2439-2444 . https://doi.org/10.1111/liv.14597
Liver International
NAFLD is closely related with the metabolic syndrome (MetS) and increased risk of cardiovascular disease. Liver fat associates with post-prandial hypertriglyceridemia, potentially contributing to triglyceride-enrichment of high-density lipoproteins (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea34d42ca6f52d8c1b17a427977a922c
https://doi.org/10.1111/liv.14597
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4
Drug withdrawal in patients with autoimmune hepatitis in long-term histological remission: A prospective observational study
Autor: Romée J. A. L. M. Snijders, Elisabeth Bloemena, Gerd Bouma, Floris F. van den Brand, Ynto S. de Boer, Carin M.J. van Nieuwkerk, Sjoerd D. Kuiken, Bart J. Verwer, Joost P.H. Drenth
Publikováno v: van den Brand, F F, Snijders, R J A L M, de Boer, Y S, Verwer, B J, van Nieuwkerk, C M J, Bloemena, E, Kuiken, S D, Drenth, J P H & Bouma, G 2021, ' Drug withdrawal in patients with autoimmune hepatitis in long-term histological remission: A prospective observational study ', European Journal of Internal Medicine, vol. 90, pp. 30-36 . https://doi.org/10.1016/j.ejim.2021.03.024
European Journal of Internal Medicine, 90, 30-36
European Journal of Internal Medicine, 90, 30-36. Elsevier
van den Brand, F F, Snijders, R J A L M, de Boer, Y S, Verwer, B J, van Nieuwkerk, C M J, Bloemena, E, Kuiken, S D, Drenth, J P H & Bouma, G 2021, ' Drug withdrawal in patients with autoimmune hepatitis in long-term histological remission : A prospective observational study ', European Journal of Internal Medicine, vol. 90, pp. 30-36 . https://doi.org/10.1016/j.ejim.2021.03.024
European journal of internal medicine, 90, 30-36. Elsevier
European Journal of Internal Medicine, 90, pp. 30-36
Background Recommendations for drug withdrawal in patients with autoimmune hepatitis (AIH) in longstanding remission are conflicting and rely on retrospective data. We prospectively investigated the predictive value of histological normalisation for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61db903bcfd94aaa25fbecc6920ea001
https://research.vumc.nl/en/publications/2894391b-d095-4877-ace1-5a7c97585858
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Plasma Cathepsin D Activity Rather Than Levels Correlates With Metabolic Parameters of Type 2 Diabetes in Male Individuals
Autor: Tom Houben, Yvonne Oligschlaeger, Bart J. Verwer, Maarten E. Tushuizen, Ronit Shiri-Sverdlov, Lingling Ding, Albert V. Bitorina
Publikováno v: Frontiers in Endocrinology
Frontiers in Endocrinology, 11:575070. Frontiers Media S.A.
Frontiers in Endocrinology, Vol 11 (2020)
Frontiers in Endocrinology, 11. FRONTIERS MEDIA SA
Objective: Type 2 diabetes mellitus is a metabolic disorder characterized by insulin resistance. Previous studies in patients demonstrated that plasma levels of cathepsin D (CTSD), which is optimally active in the acidic environment of lysosomes, cor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c82e07d7e31a745e5238155be57705
http://europepmc.org/articles/PMC7554511
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6
Biochemical efficacy of tioguanine in autoimmune hepatitis: a retrospective review of practice in the Netherlands
Autor: Frank ter Borg, Floris F. van den Brand, Adriaan C.I.T.L. Tan, Bart J. Verwer, Gerd Bouma, Nanne K. H. de Boer, Akin Inderson, Elisabeth Bloemena, J.M. Vrolijk, Ynto S. de Boer, Christine M. Bakker, Sven Van Den Hazel, Martijn J. ter Borg, Chris J. J. Mulder, Joost P.H. Drenth, Maarten E. Tushuizen, Carin M.J. van Nieuwkerk
Publikováno v: Alimentary Pharmacology & Therapeutics
Alimentary pharmacology & therapeutics, 48(7), 761-767
Alimentary Pharmacology & Therapeutics, 48, 761-767
van den Brand, F F, van Nieuwkerk, C M J, Verwer, B J, de Boer, Y S, de Boer, N K H, Mulder, C J J, Bloemena, E, Bakker, C M, Vrolijk, J M, Drenth, J P H, Tan, A C I T L, Ter Borg, F, Ter Borg, M J, van den Hazel, S J, Inderson, A, Tushuizen, M E & Bouma, G 2018, ' Biochemical efficacy of tioguanine in autoimmune hepatitis : a retrospective review of practice in the Netherlands ', Alimentary pharmacology & therapeutics, vol. 48, no. 7, pp. 761-767 . https://doi.org/10.1111/apt.14939
Alimentary Pharmacology and Therapeutics, 48(7), 761-767
Alimentary Pharmacology & Therapeutics, 48, 7, pp. 761-767
Contains fulltext : 195713.pdf (Publisher’s version ) (Open Access) BACKGROUND: Azathioprine (AZA) and mercaptopurine (MP) are the cornerstone of steroid-sparing strategies in autoimmune hepatitis (AIH). Up to 20% of patients do not tolerate or res
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e0a5ea9102d6d2aacd1e57490e9679
https://hdl.handle.net/1887/75673
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7
Role of age in presentation, response to therapy and outcome of autoimmune hepatitis
Autor: Bart J. Verwer, Martine Baven-Pronk, Maaike Biewenga, Carin M.J. van Nieuwkerk, Joanne J. van Silfhout, Gerd Bouma, Aad P. van den Berg, Henk R. van Buuren, Bart van Hoek
Publikováno v: Clinical and Translational Gastroenterology, 9:165. Nature Publishing Group
Baven-Pronk, M A M C, Biewenga, M, van Silfhout, J J, van den Berg, A P, van Buuren, H R, Verwer, B J, van Nieuwkerk, C M J, Bouma, G & van Hoek, B 2018, ' Role of age in presentation, response to therapy and outcome of autoimmune hepatitis article ', CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, vol. 9, no. 6, 165 . https://doi.org/10.1038/s41424-018-0028-1
Clinical and Translational Gastroenterology, 9
Clinical and Translational Gastroenterology
Clinical and translational gastroenterology, 9(6):165, 1-12. Nature Publishing Group
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 9(6):165. Nature Publishing Group
Background: Few studies with diverging results and a small sample size have compared autoimmune hepatitis (AIH) in the elderly to younger patients.Aim: To unbiasedly investigate the role of age in behaviour and treatment outcome of AIH.Methods: All p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c15c9945fd34403d449acd26e33e543
https://hdl.handle.net/1887/75615
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9
Relapse is almost universal after withdrawal of immunosuppressive medication in patients with autoimmune hepatitis in remission
Autor: Nicole M F, van Gerven, Bart J, Verwer, Birgit I, Witte, Bart, van Hoek, Minneke J, Coenraad, Karel J, van Erpecum, Ulrich, Beuers, Henk R, van Buuren, Rob A, de Man, Joost P H, Drenth, Jannie W, den Ouden, Robert C, Verdonk, Ger H, Koek, Johannes T, Brouwer, Maureen M J, Guichelaar, Chris J J, Mulder, Karin M J, van Nieuwkerk, Gerd, Bouma, M A M T, Verhagen
Publikováno v: van Gerven, N M F, Verwer, B J, Witte, B I, van Hoek, B, Coenraad, M J, van Erpecum, K J, Beuers, U, van Buuren, H R, de Man, R A, Drenth, J P H, den Ouden, J W, Verdonk, R C, Koek, G H, Brouwer, J T, Guichelaar, M M J, Mulder, C J J, van Nieuwkerk, C M J & Bouma, G 2013, ' Relapse is almost universal after withdrawal of immunosuppressive medication in patients with autoimmune hepatitis in remission ', Journal of Hepatology, vol. 58, no. 1, pp. 141-147 . https://doi.org/10.1016/j.jhep.2012.09.009
Journal of Hepatology, 58, 141-7
Journal of Hepatology, 58(1), 141-147. Elsevier Science
Journal of Hepatology, 58(1), 141-147
Journal of Hepatology, 58(1), 141-147. Elsevier
Journal of Hepatology, 58(1), 141-147. ELSEVIER SCIENCE BV
Journal of hepatology, 58(1), 141-147. Elsevier
Journal of Hepatology, 58, 1, pp. 141-7
Background & Aims: Current treatment strategies in autoimmune hepatitis (AIH) include long-term treatment with corticosteroids and/or azathioprine. Here we determined the risk of relapse after drug withdrawal in patients in long-term remission and fa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c908ca065c308833e67dd137bd1504
https://hdl.handle.net/1887/96970
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