Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bart H. J. van den Berg"'
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10642 (2010)
One motivation of systems biology research is to understand gene functions and interactions from functional genomics data such as that derived from microarrays. Up-to-date structural and functional annotations of genes are an essential foundation of
Externí odkaz:
https://doaj.org/article/b24a4e64d63046589c9e4ad7ec650504
Autor:
Gea Guerriero, Frank Maixner, Petra Leidinger, Thorsten Overath, Benjamin Meder, Eduard Egarter-Vigl, Albert Zink, Bjoern Stade, Andreas Tholey, Dennis Linke, Christina Backes, Eckart Meese, Andre Franke, Andreas Schwarz, Benny Kneissl, Marek Janko, Marta Jaremek, Bart H. J. van den Berg, Andreas Keller
Publikováno v:
Cellular and Molecular Life Sciences. 70:3709-3722
The Tyrolean Iceman, a Copper-age ice mummy, is one of the best-studied human individuals. While the genome of the Iceman has largely been decoded, tissue-specific proteomes have not yet been investigated. We studied the proteome of two distinct brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21b8ef285367b5eab99a6af8bcf5ba6
https://doi.org/10.1007/s00018-013-1360-y
https://doi.org/10.1007/s00018-013-1360-y
Publikováno v:
Rapid Communications in Mass Spectrometry. 26:2777-2785
RATIONALE Isobaric labeling strategies (e.g. iTRAQ or TMT) are commonly applied in tandem mass spectrometric (MS/MS) level quantitative proteomics. However, we frequently observed missing isotope reporter ion signals in a large-scale liquid chromatog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c0665b43c1a09b61851619c39ac30c5
https://doi.org/10.1002/rcm.6403
https://doi.org/10.1002/rcm.6403
Publikováno v:
Journal of Proteome Research. 11:1812-1820
Knowledge of cleavage site specificity and activity are major prerequisites for understanding protease function. On the basis of a recently presented approach for proteomic identification of cleavage sites (PICS) in proteome-derived peptide libraries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19f8681c6ab55757959879ee3e98711
https://doi.org/10.1021/pr201051e
https://doi.org/10.1021/pr201051e
Publikováno v:
PROTEOMICS. 12:516-529
Protease-catalyzed hydrolysis of peptide bonds is one of the most pivotal post-translational modifications fulfilling manifold functions in the regulation of cellular processes. Therefore, dysregulation of proteolytic reactions plays a central role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378ef011d0c838430835fb3ffd599f25
https://doi.org/10.1002/pmic.201100379
https://doi.org/10.1002/pmic.201100379
Publikováno v:
Rapid Communications in Mass Spectrometry. 21:3905-3909
Non-electrophoretic methods based on two-dimensional liquid chromatography followed directly by tandem mass spectrometry (2D-LC/MS2) have become the preferred method for high-throughput expression proteomics and are widely applied to fresh tissues. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff828aebe6c275983954dac1458af9b0
https://doi.org/10.1002/rcm.3287
https://doi.org/10.1002/rcm.3287
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10642 (2010)
PLoS ONE
PLoS ONE
One motivation of systems biology research is to understand gene functions and interactions from functional genomics data such as that derived from microarrays. Up-to-date structural and functional annotations of genes are an essential foundation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4eb533b100513b61d6d602168b1bc20
http://europepmc.org/articles/PMC2871057?pdf=render
http://europepmc.org/articles/PMC2871057?pdf=render
Publikováno v:
BMC Bioinformatics, Vol 10, Iss Suppl 11, p S9 (2009)
BMC Bioinformatics
BMC Bioinformatics
The widespread availability of microarray technology has driven functional genomics to the forefront as scientists seek to draw meaningful biological conclusions from their microarray results. Gene annotation enrichment analysis is a functional analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa93588317947f2e746a057b2b579c40
https://doaj.org/article/b584add04bc444cbaa61acbadc9ac876
https://doaj.org/article/b584add04bc444cbaa61acbadc9ac876
Publikováno v:
BMC Bioinformatics, Vol 10, Iss 1, p 30 (2009)
BMC Bioinformatics
BMC Bioinformatics
Background Systems biology modeling from microarray data requires the most contemporary structural and functional array annotation. However, microarray annotations, especially for non-commercial, non-traditional biomedical model organisms, are often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c9228d0e4191f4ff456c9d95441f03
http://www.biomedcentral.com/1471-2105/10/30
http://www.biomedcentral.com/1471-2105/10/30
Publikováno v:
Journal of proteome research. 4(2)
Differential detergent fractionation (DDF), which relies on detergents to sequentially extract proteins from eukaryotic cells, has been used to increase proteome coverage of 2D-PAGE. Here, we used DDF extraction in conjunction with the nonelectrophor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc82088b51f1b26dc6841c04d0ba43c
https://pubmed.ncbi.nlm.nih.gov/15822906
https://pubmed.ncbi.nlm.nih.gov/15822906