Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bart F. J. Heijnen"'
Autor:
Bart F J Heijnen, Jelly Nelissen, Helma van Essen, Gregorio E Fazzi, Jan W Cohen Tervaert, Carine J Peutz-Kootstra, John J Mullins, Casper G Schalkwijk, Ben J A Janssen, Harry A J Struijker-Boudier
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57815 (2013)
Transient activation of the renin-angiotensin system (RAS) induces irreversible renal damage causing sustained elevation in blood pressure (BP) in Cyp1a1-Ren2 transgenic rats. In our current study we hypothesized that activation of the AT1-receptor (
Externí odkaz:
https://doaj.org/article/525f71f65d8845759ce3f3b41dd5aaf8
Autor:
Robert Zietse, Jeanette M.G. van Gool, A.H. Jan Danser, Stephen B. Walsh, Janos Peti-Peterdi, Daisuke Nakano, Ingrid M. Garrelds, Bart F. J. Heijnen, Harry A.J. Struijker-Boudier, Lodi C.W. Roksnoer, Ewout J. Hoorn
Publikováno v:
Hypertension, 67(5), 927-933. LIPPINCOTT WILLIAMS & WILKINS
Hypertension, 67(5), 927-933. Lippincott Williams & Wilkins
Hypertension, 67(5), 927-933. Lippincott Williams & Wilkins
Urinary angiotensinogen excretion parallels albumin excretion, which is not the case for renin, while renin's precursor, prorenin, is undetectable in urine. We hypothesized that renin and prorenin, given their smaller size, are filtered through the g
Autor:
Harry A.J. Struijker-Boudier, Helma van Essen, Casper G. Schalkwijk, Ben J. A. Janssen, Bart F. J. Heijnen
Publikováno v:
Hypertension Research, 37(2), 100-109. Nature Publishing Group
Early blockade of the renin-angiotensin system is successful in delaying the development of hypertension in spontaneously hypertensive rats (SHRs) and ameliorating organ damage by inhibition of the inflammatory response. In this study, we investigate
Autor:
John J. Mullins, Harry A.J. Struijker-Boudier, A.H. Jan Danser, Jo G. R. De Mey, Bart F. J. Heijnen, Leonie Pelkmans, Ben J. A. Janssen, Ingrid M. Garrelds
Publikováno v:
Heijnen, B F, Pelkmans, L P, Danser, A J, Garrelds, I M, Mullins, J J, De Mey, J G, Struijker-Boudier, H A & Janssen, B J 2014, ' Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats ', Journal of the Renin-Angiotensin-Aldosterone System, vol. 15, no. 1, pp. 69-81 . https://doi.org/10.1177/1470320313480537
Journal of the Renin-Angiotensin-Aldosterone System, 15(1), 69-81. SAGE Publications Ltd
Journal of the Renin-angiotensin-aldosterone System, 15(1), 69-81. SAGE Publications Inc.
Journal of the Renin-Angiotensin-Aldosterone System, Vol 15 (2014)
Journal of the Renin-Angiotensin-Aldosterone System, 15(1), 69-81. SAGE Publications Ltd
Journal of the Renin-angiotensin-aldosterone System, 15(1), 69-81. SAGE Publications Inc.
Journal of the Renin-Angiotensin-Aldosterone System, Vol 15 (2014)
This study investigated renin-angiotensin system (RAS)-induced cardiac remodeling and its reversibility in the presence and absence of high blood pressure (BP) in Cyp1a1-Ren2 transgenic inducible hypertensive rats (IHR). In IHR (pro)renin levels and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96d96e1b55b45cabaaef2e99e829254
https://portal.findresearcher.sdu.dk/da/publications/bb5568dd-21e8-4426-b3ea-5ad235001cbe
https://portal.findresearcher.sdu.dk/da/publications/bb5568dd-21e8-4426-b3ea-5ad235001cbe
Publikováno v:
Hypertension, 60(2), 523-527. LIPPINCOTT WILLIAMS & WILKINS
The role of the microcirculation is increasingly being recognized in the pathophysiology of cardiovascular disease.1,2 The microcirculation is a major site of damage in most target organs of cardiovascular disease, such as the heart, brain, and kidne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da9b322dbbbb15df82657cdbafef3e4
https://cris.maastrichtuniversity.nl/en/publications/ce89920d-850f-4ff4-a639-b21f0f4460f1
https://cris.maastrichtuniversity.nl/en/publications/ce89920d-850f-4ff4-a639-b21f0f4460f1
Autor:
Jan H Danser, John J. Mullins, Harry A.J. Struijker-Boudier, Ingrid M. Garrelds, Leonie Pelkmans, Bart F. J. Heijnen, Jo G. R. De Mey, Ben J. A. Janssen
Publikováno v:
The FASEB Journal. 26
Publikováno v:
Special Issues in Hypertension ISBN: 9788847026001
The role of the microcirculation is increasingly being recognized in the pathophysiology of cardiovascular disease. It is the major site of control of vascular resistance. In addition, the microcirculation is a major site of damage in most target org
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ec579f649b1431660f9f0ce5915f127
https://doi.org/10.1007/978-88-470-2601-8_17
https://doi.org/10.1007/978-88-470-2601-8_17
Autor:
Bart F. J. Heijnen, Harry A.J. Struijker-Boudier, John J. Mullins, Ben J. A. Janssen, Carine J. Peutz-Kootstra
Publikováno v:
Journal of Hypertension, 29(12), 2369-2380. LIPPINCOTT WILLIAMS & WILKINS
Objectives Transient administration of inhibitors of the renin-angiotensin system (RAS) during the prehypertensive period in rats and humans leads to a long-lasting lowering of blood pressure (BP). Our aim was to unravel the critical period in which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096d275e9d22cbaf3109c3edc5e9f8ca
https://cris.maastrichtuniversity.nl/en/publications/85def0ad-89c8-461b-9fb5-b590d7a5c52c
https://cris.maastrichtuniversity.nl/en/publications/85def0ad-89c8-461b-9fb5-b590d7a5c52c
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 58(5)
See related article, pp 847–851 Research in the past decades has established a key role for the intrauterine environment, especially the maternal nutritional status, in influencing fetal growth and cardiovascular health in the offspring in later li
Autor:
Peter Lijnen, Jacques Debets, Helma van Essen, Ben J. A. Janssen, Carine J. Peutz-Kootstra, Harry A.J. Struijker-Boudier, Bart F. J. Heijnen
Publikováno v:
The FASEB Journal. 24