Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Bart F. J. Heijnen"'
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Akademický článek
Irreversible renal damage after transient renin-angiotensin system stimulation: involvement of an AT1-receptor mediated immune response.
Autor: Bart F J Heijnen, Jelly Nelissen, Helma van Essen, Gregorio E Fazzi, Jan W Cohen Tervaert, Carine J Peutz-Kootstra, John J Mullins, Casper G Schalkwijk, Ben J A Janssen, Harry A J Struijker-Boudier
Publikováno v: PLoS ONE, Vol 8, Iss 2, p e57815 (2013)
Transient activation of the renin-angiotensin system (RAS) induces irreversible renal damage causing sustained elevation in blood pressure (BP) in Cyp1a1-Ren2 transgenic rats. In our current study we hypothesized that activation of the AT1-receptor (
Externí odkaz: https://doaj.org/article/525f71f65d8845759ce3f3b41dd5aaf8
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2
On the Origin of Urinary Renin A Translational Approach
Autor: Robert Zietse, Jeanette M.G. van Gool, A.H. Jan Danser, Stephen B. Walsh, Janos Peti-Peterdi, Daisuke Nakano, Ingrid M. Garrelds, Bart F. J. Heijnen, Harry A.J. Struijker-Boudier, Lodi C.W. Roksnoer, Ewout J. Hoorn
Publikováno v: Hypertension, 67(5), 927-933. LIPPINCOTT WILLIAMS & WILKINS
Hypertension, 67(5), 927-933. Lippincott Williams & Wilkins
Urinary angiotensinogen excretion parallels albumin excretion, which is not the case for renin, while renin's precursor, prorenin, is undetectable in urine. We hypothesized that renin and prorenin, given their smaller size, are filtered through the g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495e77038e8f8ce88da88be431f3623e
https://cris.maastrichtuniversity.nl/en/publications/2672c01a-8634-419a-9c3d-01c4484eadec
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3
Renal inflammatory markers during the onset of hypertension in spontaneously hypertensive rats
Autor: Harry A.J. Struijker-Boudier, Helma van Essen, Casper G. Schalkwijk, Ben J. A. Janssen, Bart F. J. Heijnen
Publikováno v: Hypertension Research, 37(2), 100-109. Nature Publishing Group
Early blockade of the renin-angiotensin system is successful in delaying the development of hypertension in spontaneously hypertensive rats (SHRs) and ameliorating organ damage by inhibition of the inflammatory response. In this study, we investigate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eca1122120f2623dcd4d319054874aa
https://doi.org/10.1038/hr.2013.99
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4
Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats
Autor: John J. Mullins, Harry A.J. Struijker-Boudier, A.H. Jan Danser, Jo G. R. De Mey, Bart F. J. Heijnen, Leonie Pelkmans, Ben J. A. Janssen, Ingrid M. Garrelds
Publikováno v: Heijnen, B F, Pelkmans, L P, Danser, A J, Garrelds, I M, Mullins, J J, De Mey, J G, Struijker-Boudier, H A & Janssen, B J 2014, ' Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats ', Journal of the Renin-Angiotensin-Aldosterone System, vol. 15, no. 1, pp. 69-81 . https://doi.org/10.1177/1470320313480537
Journal of the Renin-Angiotensin-Aldosterone System, 15(1), 69-81. SAGE Publications Ltd
Journal of the Renin-angiotensin-aldosterone System, 15(1), 69-81. SAGE Publications Inc.
Journal of the Renin-Angiotensin-Aldosterone System, Vol 15 (2014)
This study investigated renin-angiotensin system (RAS)-induced cardiac remodeling and its reversibility in the presence and absence of high blood pressure (BP) in Cyp1a1-Ren2 transgenic inducible hypertensive rats (IHR). In IHR (pro)renin levels and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96d96e1b55b45cabaaef2e99e829254
https://portal.findresearcher.sdu.dk/da/publications/bb5568dd-21e8-4426-b3ea-5ad235001cbe
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5
Phenotyping the Microcirculation
Autor: Harry A.J. Struijker-Boudier, Jan A. Staessen, Yan-Ping Liu, Bart F. J. Heijnen
Publikováno v: Hypertension, 60(2), 523-527. LIPPINCOTT WILLIAMS & WILKINS
The role of the microcirculation is increasingly being recognized in the pathophysiology of cardiovascular disease.1,2 The microcirculation is a major site of damage in most target organs of cardiovascular disease, such as the heart, brain, and kidne
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da9b322dbbbb15df82657cdbafef3e4
https://cris.maastrichtuniversity.nl/en/publications/ce89920d-850f-4ff4-a639-b21f0f4460f1
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7
The Microcirculation and Hypertension
Autor: Harry A.J. Struijker-Boudier, Bart F. J. Heijnen
Publikováno v: Special Issues in Hypertension ISBN: 9788847026001
The role of the microcirculation is increasingly being recognized in the pathophysiology of cardiovascular disease. It is the major site of control of vascular resistance. In addition, the microcirculation is a major site of damage in most target org
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ec579f649b1431660f9f0ce5915f127
https://doi.org/10.1007/978-88-470-2601-8_17
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8
Transient renin-angiotensin system stimulation in an early stage of life causes sustained hypertension in rats
Autor: Bart F. J. Heijnen, Harry A.J. Struijker-Boudier, John J. Mullins, Ben J. A. Janssen, Carine J. Peutz-Kootstra
Publikováno v: Journal of Hypertension, 29(12), 2369-2380. LIPPINCOTT WILLIAMS & WILKINS
Objectives Transient administration of inhibitors of the renin-angiotensin system (RAS) during the prehypertensive period in rats and humans leads to a long-lasting lowering of blood pressure (BP). Our aim was to unravel the critical period in which
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096d275e9d22cbaf3109c3edc5e9f8ca
https://cris.maastrichtuniversity.nl/en/publications/85def0ad-89c8-461b-9fb5-b590d7a5c52c
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9
Early life microcirculation and the development of hypertension
Autor: Harry A.J. Struijker-Boudier, Bart F. J. Heijnen
Publikováno v: Hypertension (Dallas, Tex. : 1979). 58(5)
See related article, pp 847–851 Research in the past decades has established a key role for the intrauterine environment, especially the maternal nutritional status, in influencing fetal growth and cardiovascular health in the offspring in later li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2c45898d6dd18968ed28e45262263d
https://pubmed.ncbi.nlm.nih.gov/21968755
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