Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Bart De Jong"'
Autor:
Leonardo Geronzi, Benigno Marco Fanni, Bart De Jong, Gerben Roest, Sasa Kenjeres, Simona Celi, Marco Evangelos Biancolini
Publikováno v:
Fluids, Vol 9, Iss 1, p 27 (2024)
The treatment for asthma and chronic obstructive pulmonary disease relies on forced inhalation of drug particles. Their distribution is essential for maximizing the outcomes. Patient-specific computational fluid dynamics (CFD) simulations can be used
Externí odkaz:
https://doaj.org/article/6cdf948a26e54f65925b1acc66f950ad
Autor:
Patrick J. Engelberts, Ida H. Hiemstra, Bart de Jong, Danita H. Schuurhuis, Joyce Meesters, Irati Beltran Hernandez, Simone C. Oostindie, Joost Neijssen, Edward N. van den Brink, G. Jean Horbach, Sandra Verploegen, Aran F. Labrijn, Theodora Salcedo, Janine Schuurman, Paul W.H.I Parren, Esther C.W. Breij
Publikováno v:
EBioMedicine, Vol 52, Iss , Pp - (2020)
Background: DuoBody®-CD3xCD20 (GEN3013) is a full-length human IgG1 bispecific antibody (bsAb) recognizing CD3 and CD20, generated by controlled Fab-arm exchange. Its Fc domain was silenced by introduction of mutations L234F L235E D265A. Methods: T-
Externí odkaz:
https://doaj.org/article/8eed60dbcc62461eb9d7224a1bb469dc
Autor:
Gerben J. Schaaf, Tom J. M. van Gestel, Stijn L. M. in ‘t Groen, Bart de Jong, Björn Boomaars, Antonietta Tarallo, Monica Cardone, Giancarlo Parenti, Ans T. van der Ploeg, W. W. M. Pim Pijnappel
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-16 (2018)
Abstract Pompe disease is a metabolic myopathy that is caused by glycogen accumulation as a result of deficiency of the lysosomal enzyme acid alpha glucosidase (GAA). Previously, we showed that adult muscle stem cells termed satellite cells are prese
Externí odkaz:
https://doaj.org/article/f51a553464da4d30a7d8d9011a9721bd
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1006 (2020)
Extracellular vesicles (EVs) are membrane-bilayered nanoparticles released by most cell types. Recently, an enormous number of studies have been published on the potential of EVs as carriers of therapeutic agents. In contrast to systems such as lipos
Externí odkaz:
https://doaj.org/article/db8828655c2d4114a716bba1e4d714e8
Autor:
Simone C. Oostindie, Derek A. Rinaldi, Gijs G. Zom, Michael J. Wester, Desiree Paulet, Kusai Al-Tamimi, Els van der Meijden, Jennifer R. Scheick, Tessa Wilpshaar, Bart de Jong, Marloes Hoff-van den Broek, Rachel M. Grattan, Janita J. Oosterhoff, Julie Vignau, Sandra Verploegen, Peter Boross, Frank J. Beurskens, Diane S. Lidke, Janine Schuurman, Rob N. de Jong
Publikováno v:
Nature Biotechnology. 40:1509-1519
The use of therapeutic monoclonal antibodies is constrained because single antigen targets often do not provide sufficient selectivity to distinguish diseased from healthy tissues. We present HexElect®, an approach to enhance the functional selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37adbdc10c2c7fdd110d991a2ca6fa2f
https://doi.org/10.1038/s41587-022-01384-1
https://doi.org/10.1038/s41587-022-01384-1
Autor:
Esther C.W. Breij, Rob N. de Jong, Paul W.H.I. Parren, Janine Schuurman, Ulf Forssmann, Andreas Lingnau, Richard G. Hibbert, Naomi Hoevenaars, Bart de Jong, Thessa Kroes, Boris S. Vuillermoz, Claudine Vermot-Desroches, Antonio Ortiz Buijsse, Frank J. Beurskens, Kristin Strumane, Marije B. Overdijk
Supplemental Tables Supplemental Figures Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc0742629adc9c9f5ee0bce476596b4
https://doi.org/10.1158/1535-7163.22520991.v1
https://doi.org/10.1158/1535-7163.22520991.v1
Autor:
Esther C.W. Breij, Rob N. de Jong, Paul W.H.I. Parren, Janine Schuurman, Ulf Forssmann, Andreas Lingnau, Richard G. Hibbert, Naomi Hoevenaars, Bart de Jong, Thessa Kroes, Boris S. Vuillermoz, Claudine Vermot-Desroches, Antonio Ortiz Buijsse, Frank J. Beurskens, Kristin Strumane, Marije B. Overdijk
Higher-order death receptor 5 (DR5) clustering can induce tumor cell death; however, therapeutic compounds targeting DR5 have achieved limited clinical efficacy. We describe HexaBody-DR5/DR5, an equimolar mixture of two DR5-specific IgG1 antibodies w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f853ed6f8830a1d4904eeb661710e2
https://doi.org/10.1158/1535-7163.c.6542862.v1
https://doi.org/10.1158/1535-7163.c.6542862.v1
Publikováno v:
Academy of Management Proceedings. 2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993183fd4f248d5a3f3208128788cf8f
https://doi.org/10.5465/ambpp.2022.17339symposium
https://doi.org/10.5465/ambpp.2022.17339symposium
Publikováno v:
Chemical communications (Cambridge, England), 56(95), 14992-14995. ROYAL SOC CHEMISTRY
We report a cost-effective, straightforward synthesis of a novel electrocatalyst for the reduction of CO2to formate, which achieves nearly complete Faradaic efficiency (FE) at an overpotential (η) of 0.88 V under ambient conditions. The electrocatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec3d85d8b8ef8fe72e9cc88af66ffe4
https://research.rug.nl/en/publications/d1f5db29-2641-44de-b90a-e59da64e3e30
https://research.rug.nl/en/publications/d1f5db29-2641-44de-b90a-e59da64e3e30
Publikováno v:
Journal of Management. 47:2135-2168
Despite tremendous progress toward understanding trust within teams, research has predominately conceptualized team trust as a shared group construct, focusing almost exclusively on trust magnitude (i.e., mean level of trust) while ignoring trust dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bcc9ff78c0f347149f3bddb3f56fbc
https://doi.org/10.1177/0149206320943658
https://doi.org/10.1177/0149206320943658