Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bart A, Lutterbach"'
Autor:
Ahmed A. Samatar, Stephen Fawell, Leigh Zawel, Lata Jayaraman, D. Gary Gilliland, Daniel Hicklin, W. Robert Bishop, Paul Kirschmeier, David Witter, Phieng Siliphaivanh, Ulrike Philippar, Marc R. Pelletier, Bart A. Lutterbach, Ling Zhang, Pierre Daublain, Liang Zhu, Boga Sobhana Babu, Xiaolei Gao, Sunil Paliwal, Joe Kelly, James Wang, Alan Hruza, Gerald Shipps, Li Xiao, Jagdish Desai, Elaine M. Pinheiro, Minilik H. Angagaw, Shuxia Zhao, Rumin Zhang, William Windsor, Edward DiNunzio, Jenny Liu, Brian Long, Stuart Black, Weihong Jin, Yongi Deng, Donna Carr, Alan Cooper, Hugh Zhu, Priya Dayananth, Clifford R. Restaino, Sharda Jha, Erick J. Morris
Supplementary Figures - PDF file 1385K, File contains Supplementary figures of resistant cell lines, proliferation assay of a panel of cell lines, TdF binding assay transcriptional out and kinome selectivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043d9dc9ddac3082860a77d7c7fbd235
https://doi.org/10.1158/2159-8290.22530809
https://doi.org/10.1158/2159-8290.22530809
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Figure 3 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ead8a2c84ec1e9b5c7fd484d5aa73e
https://doi.org/10.1158/0008-5472.22383779
https://doi.org/10.1158/0008-5472.22383779
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Figure 4 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054140e8884713105eec245eadc1cdda
https://doi.org/10.1158/0008-5472.22383776
https://doi.org/10.1158/0008-5472.22383776
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Figure 2 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a65a09f92681267a6de3aaaa88df405
https://doi.org/10.1158/0008-5472.22383782
https://doi.org/10.1158/0008-5472.22383782
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Figure 1 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d584751769fb485b613b5d4da0b8ad
https://doi.org/10.1158/0008-5472.22383785
https://doi.org/10.1158/0008-5472.22383785
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Figure 5 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698732c4b28be2c0e774afa90e7f46c3
https://doi.org/10.1158/0008-5472.22383773.v1
https://doi.org/10.1158/0008-5472.22383773.v1
Autor:
Christopher J. Dinsmore, Nancy E. Kohl, Qinwen Zeng, Alexander A. Szewczak, John F. Reilly, Xianlu Qu, Cloud P. Paweletz, Bart A. Lutterbach, Wei Lu, Kaiko Kunii, Jason D. Katz, Ilona Kariv, James P. Jewell, Harold Hatch, Gaozhen Hang, Susana Gil, Jackson B. Gibbs, Sujal V. Deshmukh, Lenora J. Davis, An Chi, Melissa Chenard, Grace K.Y. Chan, Bo-Sheng Pan
Supplementary Methods, Table 1, Figure Legends 1-5 from MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4bf79ff1fd442ca0667d231c5117b6
https://doi.org/10.1158/0008-5472.22383770.v1
https://doi.org/10.1158/0008-5472.22383770.v1
Autor:
Kumiko, Nagashima, Stuart D, Shumway, Sriram, Sathyanarayanan, Albert H, Chen, Brian, Dolinski, Youyuan, Xu, Heike, Keilhack, Thi, Nguyen, Maciej, Wiznerowicz, Lixia, Li, Bart A, Lutterbach, An, Chi, Cloud, Paweletz, Timothy, Allison, Youwei, Yan, Sanjeev K, Munshi, Anke, Klippel, Manfred, Kraus, Ekaterina V, Bobkova, Sujal, Deshmukh, Zangwei, Xu, Uwe, Mueller, Alexander A, Szewczak, Bo-Sheng, Pan, Victoria, Richon, Roy, Pollock, Peter, Blume-Jensen, Alan, Northrup, Jannik N, Andersen
Phosphoinositide-dependent kinase 1 (PDK1) is a critical activator of multiple prosurvival and oncogenic protein kinases and has garnered considerable interest as an oncology drug target. Despite progress characterizing PDK1 as a therapeutic target,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffa77558274950b04bf7d0ff36cc73f0
http://hdl.handle.net/10722/156005
http://hdl.handle.net/10722/156005