Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Bart, Deplancke"'
Autor:
Ertunc Erdil, Anton S. Becker, Moritz Schwyzer, Borja Martinez-Tellez, Jonatan R. Ruiz, Thomas Sartoretti, H. Alberto Vargas, A. Irene Burger, Alin Chirindel, Damian Wild, Nicola Zamboni, Bart Deplancke, Vincent Gardeux, Claudia Irene Maushart, Matthias Johannes Betz, Christian Wolfrum, Ender Konukoglu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The standard method for identifying active Brown Adipose Tissue (BAT) is [18F]-Fluorodeoxyglucose ([18F]-FDG) PET/CT imaging, which is costly and exposes patients to radiation, making it impractical for population studies. These issues can b
Externí odkaz:
https://doaj.org/article/c805cb8195b94f0d8b4205323cae48a9
Autor:
Olga Pushkarev, Guido van Mierlo, Judith Franziska Kribelbauer, Wouter Saelens, Vincent Gardeux, Bart Deplancke
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-32 (2024)
Abstract Background Interactions among cis-regulatory elements (CREs) play a crucial role in gene regulation. Various approaches have been developed to map these interactions genome-wide, including those relying on interindividual epigenomic variatio
Externí odkaz:
https://doaj.org/article/c50711ddf2284a3dbc0ccd08db72a7ee
Autor:
Vincent Gardeux, Roel PJ Bevers, Fabrice PA David, Emily Rosschaert, Romain Rochepeau, Bart Deplancke
Publikováno v:
eLife, Vol 12 (2024)
Genome-wide association studies have advanced our understanding of complex traits, but studying how a GWAS variant can affect a specific trait in the human population remains challenging due to environmental variability. Drosophila melanogaster is in
Externí odkaz:
https://doaj.org/article/e8a562e0772941bab3fddb082bbb5545
Autor:
Ertunc Erdil, Anton S. Becker, Moritz Schwyzer, Borja Martinez-Tellez, Jonatan R. Ruiz, Thomas Sartoretti, H. Alberto Vargas, A. Irene Burger, Alin Chirindel, Damian Wild, Nicola Zamboni, Bart Deplancke, Vincent Gardeux, Claudia Irene Maushart, Matthias Johannes Betz, Christian Wolfrum, Ender Konukoglu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/ff63f7a659df430294cb58110e985fa8
Autor:
Maria Polychronidou, Jingyi Hou, M Madan Babu, Prisca Liberali, Ido Amit, Bart Deplancke, Galit Lahav, Shalev Itzkovitz, Matthias Mann, Julio Saez‐Rodriguez, Fabian Theis, Roland Eils
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 7, Pp 1-5 (2023)
Graphical Abstract In this Editorial, our Chief Editor and members of our Advisory Editorial Board discuss recent breakthroughs, current challenges, and emerging opportunities in single‐cell biology and share their vision of “where the field is h
Externí odkaz:
https://doaj.org/article/7ddb6c78b1e24454801a548f8ec9f20e
Autor:
Joern Pezoldt, Carolin Wiechers, Mangge Zou, Maria Litovchenko, Marjan Biocanin, Michael Beckstette, Katarzyna Sitnik, Martina Palatella, Guido van Mierlo, Wanze Chen, Vincent Gardeux, Stefan Floess, Maria Ebel, Julie Russeil, Panagiota Arampatzi, Ehsan Vafardanejad, Antoine-Emmanuel Saliba, Bart Deplancke, Jochen Huehn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Lymph nodes in various locations of the body differ in their cell composition and gene expression signatures. Here authors show that the rapid postnatal expansion of lymph nodes is governed by CD34 + stromal cells and fibroblastic reticular stromal c
Externí odkaz:
https://doaj.org/article/a6cebd9a2df24f8cacb6093aef1fff24
Autor:
Seungjae Lee, Yen-Chung Chen, FCA Consortium, Austin E. Gillen, J. Matthew Taliaferro, Bart Deplancke, Hongjie Li, Eric C. Lai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Single cell data provides cellular resolution on gene expression, but is rarely mined for isoforms. Analysis of 3' isoforms across ~250 Drosophila cell types reveals the cellular bases for numerous tissue-specific 3' programs, identifies new 3' progr
Externí odkaz:
https://doaj.org/article/819428a6b3ea4eb7910be5712585850b
Autor:
Gerard Llimos, Vincent Gardeux, Ute Koch, Judith F. Kribelbauer, Antonina Hafner, Daniel Alpern, Joern Pezoldt, Maria Litovchenko, Julie Russeil, Riccardo Dainese, Riccardo Moia, Abdurraouf Mokhtar Mahmoud, Davide Rossi, Gianluca Gaidano, Christoph Plass, Pavlo Lutsik, Clarissa Gerhauser, Sebastian M. Waszak, Alistair Boettiger, Freddy Radtke, Bart Deplancke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Non-coding variants can regulate transcription factor binding and gene expression at variable chromatin modules. Here, the authors show that a germline variant induces transcription factor nucleation through chromatin compaction leading to AXIN2 up-r
Externí odkaz:
https://doaj.org/article/a45f0167b2ac4647bf70d5df2f44a6e7
Autor:
Silvia A. Fuertes Marraco, Daniel Alpern, Sébastien Lofek, Joao Lourenco, Amandine Bovay, Hélène Maby-El Hajjami, Mauro Delorenzi, Bart Deplancke, Daniel E. Speiser
Publikováno v:
Current Research in Immunology, Vol 3, Iss , Pp 1-12 (2022)
CD8 T cells have multiple functional properties that mediate acute phase and long-term immune protection. Several effector and memory CD8 T cell subsets have been described with diverse functionalities and marker profiles. In contrast to the many com
Externí odkaz:
https://doaj.org/article/78830f8be68b440598d202caaf24f4d4
Autor:
Joern Pezoldt, Carolin Wiechers, Florian Erhard, Ulfert Rand, Tanja Bulat, Michael Beckstette, Andrea Brendolan, Jochen Huehn, Ulrich Kalinke, Mathias Mueller, Birgit Strobl, Bart Deplancke, Luka Čičin-Šain, Katarzyna M. Sitnik
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Joern Pezoldt et al. analyze mouse spleen fibroblasts using single cell RNA sequencing, revealing 11 distinct clusters of fibroblastic cells or subtypes. Their results collectively provide further insight into the transcriptional identities of spleni
Externí odkaz:
https://doaj.org/article/a39bfb883b614159a6fc0d605a03133d