Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Barry Wiggs"'
Publikováno v:
Journal of Biomechanical Engineering. 124:334-341
A two-layer model is used to simulate the mechanical behavior of an airway or other biological vessel under external compressive stress or smooth muscle constriction sufficient to cause longitudinal mucosal buckling. Analytic and finite element numer
Publikováno v:
Journal of Applied Physiology. 92:1261-1266
Alterations in airway wall anatomic properties and the consequential effects on airway narrowing have been assessed by use of computational models. In these models, it is generally assumed that at zero transmural pressure the airway wall exists in a
Publikováno v:
Academic Radiology. 6:419-425
Rationale and Objectives. The authors performed this study to determine if there were differences in vascular caliber measured on angiograms obtained with the injection protocol used for spiral computed tomography (CT) versus that used for pulmonary
Autor:
James C. Hogg, Betty Y. Poon, Christopher M. Goddard, Keith R. Walley, M. Emilia Klut, Barry Wiggs, Stephan F. vanEeden
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 275:H1548-H1557
Our goal was to determine whether coronary leukocyte retention after endotoxin infusion was due primarily to leukocyte activation. Leukocytes were activated by infusion of endotoxin into 12 blood donor rabbits. Separately, 12 isolated rabbit hearts w
Publikováno v:
The American Journal of Surgery. 175:403-407
BACKGROUND: With the prevalence of antibiotic use, the diagnosis and management of Clostridium difficile disease requires assessment. METHODS: In a retrospective review, patients wits a positive culture, toxin, or both during 1 year were identified.
Autor:
David C. Walker, Jeffrey K. Rains, Clive R. Roberts, Peter D. Paré, Barry Wiggs, Joel L. Bert
Publikováno v:
Journal of Biomechanics. 31:81-86
The cartilage of the walls of the trachea and bronchi acts to keep these airways open despite intrathoracic pressure differences during breathing that would otherwise collapse them and limit air flow. Changes in biomechanical properties and compositi
Autor:
Barry Wiggs, Blair Walker, Maleki Daya, Stephan F. van Eeden, Maria E. Klut, Darlene M. Redenbach, Yuko Kitagawa, James C. Hogg
Publikováno v:
Journal of Applied Physiology. 82:1397-1405
Kitagawa, Yuko, Stephan F. Van Eeden, Darlene M. Redenbach, Maleki Daya, Blair A. M. Walker, Maria E. Klut, Barry R. Wiggs, and James C. Hogg. Effect of mechanical deformation on structure and function of polymorphonuclear leukocytes. J. Appl. Physio
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 155:1021-1026
Chronic cigarette smoking produces a 20 to 25% increase in the number of peripheral blood leukocytes, and there is increasing evidence that these leukocytes are activated in the lung by the inhalation of cigarette smoke. The present study was designe
Publikováno v:
British Journal of Pharmacology. 120:883-891
In neural tissue, leukaemia inhibitory factor (LIF) is an important trophic cytokine. In this investigation, we determined if LIF was present in human and guinea-pig airways and examined the role of this cytokine in modulating airway responses to end
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 154:1444-1449
Nonspecific bronchial hyperresponsiveness (NSBH) occurs in asthmatics and in smokers who have airway obstruction. NSBH may be caused by different mechanisms in these conditions. We hypothesized that NSBH in smokers was a consequence of the structural