Zobrazeno 1 - 10
of 347
pro vyhledávání: '"Barry T. Rouse"'
Autor:
Shalini Sharma, Naveen Kumar, Barry T. Rouse, Khushbu Sharma, Kundan Kumar Chaubey, ShoorVir Singh, Praveen Kumar, Pradeep Kumar
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28663- (2024)
Immune exhaustion is a state of immune cell dysfunction that occurs most commonly following chronic exposure to an antigen which persists after the immune response fails to remove it. Exhaustion has been studied most thoroughly with several cancers,
Externí odkaz:
https://doaj.org/article/e3e05b89960a46f686f634a2bbbc2f68
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3935 (2024)
The mission of this review is to identify immune-damaging participants involved in antiviral immunoinflammatory lesions. We argue these could be targeted and their activity changed selectively by maneuvers that, at the same time, may not diminish the
Externí odkaz:
https://doaj.org/article/4974dde0f58f495a90bb3f4877c5f394
Publikováno v:
Pathogens, Vol 12, Iss 3, p 437 (2023)
Herpes simplex virus type 1 (HSV-1) is a highly successful pathogen that primarily infects epithelial cells of the orofacial mucosa. After initial lytic replication, HSV-1 enters sensory neurons and undergoes lifelong latency in the trigeminal gangli
Externí odkaz:
https://doaj.org/article/e77fef5996cb47278471a3fc69a1c4dc
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
The human race has survived many epidemics and pandemics that have emerged and reemerged throughout history. The novel coronavirus Severe Acute Respiratory Syndrome SARS-CoV-2/COVID-19 is the latest pandemic and this has caused major health and socio
Externí odkaz:
https://doaj.org/article/fb4af2b6185d4d14bc18e6d1a36c067e
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
When viruses infect cells, they almost invariably cause metabolic changes in the infected cell as well as in several host cell types that react to the infection. Such metabolic changes provide potential targets for therapeutic approaches that could r
Externí odkaz:
https://doaj.org/article/b0476884a1c6465190f51bef523ca751
Autor:
Barry T. Rouse, D. Scott Schmid
Publikováno v:
Viruses, Vol 14, Iss 5, p 862 (2022)
Although the establishment, maintenance and reactivation from alphaherpesvirus latency is far from fully understood, some things are now manifestly clear: Alphaherpesvirus latency occurs in neurons of the peripheral nervous system and control of the
Externí odkaz:
https://doaj.org/article/ae31da6a809c4ce2bee6686a80edcd99
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
COVID-19 has become difficult to contain in our interconnected world. In this article, we discuss some approaches that could reduce the consequences of COVID-19. We elaborate upon the utility of camelid single-domain antibodies (sdAbs), also referred
Externí odkaz:
https://doaj.org/article/7493948b89924ecba9b42c1f6a31f532
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Humans and animals are infected by multiple endogenous and exogenous viruses but few agents cause overt tissue damage. We review the circumstances which favor overt disease expression. These can include intrinsic virulence of the agent, new agents ac
Externí odkaz:
https://doaj.org/article/c239f45b85e64a379c74e86186fb3e8b
Autor:
Naveen K. Rajasagi, Barry T. Rouse
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The blinding inflammatory lesion stromal keratitis (SK), which occurs in some patients in response to ocular herpes simplex virus (HSV) infection, represents mainly an immune cell mediated inflammatory response to the virus infection. The principal o
Externí odkaz:
https://doaj.org/article/d1b193186a034b56aed7552d73a9c475
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Most vertebrates are infected with one or more herpesviruses and remain so for the rest of their lives. The relationship of immunocompetent healthy host with herpesviruses may sometime be considered as harmonious. However, clinically severe diseases
Externí odkaz:
https://doaj.org/article/2d6586c287b44de8904524e23d49f696