Using diverse U.S. beef cattle genomes to identify missense mutations in EPAS1, a gene associated with pulmonary hypertension [version 2; referees: 2 approved]

Autor: Michael P. Heaton, Timothy P.L. Smith, Jacky K. Carnahan, Veronica Basnayake, Jiansheng Qiu, Barry Simpson, Theodore S. Kalbfleisch

Publikováno v: F1000Research, Vol 5 (2016)

The availability of whole genome sequence (WGS) data has made it possible to discover protein variants in silico. However, existing bovine WGS databases do not show data in a form conducive to protein variant analysis, and tend to under represent the

Externí odkaz: https://doaj.org/article/b593d31d6bbc4d7fb4e139f7b5f0556f

Optimal Design of Low-Density SNP Arrays for Genomic Prediction: Algorithm and Applications.

Autor: Xiao-Lin Wu, Jiaqi Xu, Guofei Feng, George R Wiggans, Jeremy F Taylor, Jun He, Changsong Qian, Jiansheng Qiu, Barry Simpson, Jeremy Walker, Stewart Bauck

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0161719 (2016)

Low-density (LD) single nucleotide polymorphism (SNP) arrays provide a cost-effective solution for genomic prediction and selection, but algorithms and computational tools are needed for the optimal design of LD SNP chips. A multiple-objective, local

Externí odkaz: https://doaj.org/article/22f2eb8f36df4c4db5be758d72a1bed7

Genetic testing for TMEM154 mutations associated with lentivirus susceptibility in sheep.

Autor: Michael P Heaton, Theodore S Kalbfleisch, Dustin T Petrik, Barry Simpson, James W Kijas, Michael L Clawson, Carol G Chitko-McKown, Gregory P Harhay, Kreg A Leymaster, International Sheep Genomics Consortium

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e55490 (2013)

In sheep, small ruminant lentiviruses cause an incurable, progressive, lymphoproliferative disease that affects millions of animals worldwide. Known as ovine progressive pneumonia virus (OPPV) in the U.S., and Visna/Maedi virus (VMV) elsewhere, these

Externí odkaz: https://doaj.org/article/d621bf3cbf3d4ae58c392978b1e47d3f

SNPchiMp v.3: integrating and standardizing single nucleotide polymorphism data for livestock species

Autor: Paolo Cozzi, Chandrasen Soans, Ali Pirani, Hossein Jorjani, Alessandra Stella, Rudiger Brauning, John L. Williams, Fiona Brew, Cindy Lawley, Gwenola Tosser-Klopp, Barry Simpson, G. Evans, Nelson Nazzicari, Andrea Caprera, Francesco Strozzi, Ezequiel L. Nicolazzi

Publikováno v: BMC Genomics
BMC Genomics, BioMed Central, 2015, 16 (Online), non paginé. ⟨10.1186/s12864-015-1497-1⟩
BMC Genomics Online (16), non paginé. (2015)
BMC genomics 16 (2015). doi:10.1186/s12864-015-1497-1
info:cnr-pdr/source/autori:Nicolazzi E.L.; Caprera A.; Nazzicari N.; Cozzi P.; Strozzi F.; Lawley C.; Pirani A.; Soans C.; Brew F.; Jorjani H.; Evans G.; Simpson B.; Tosser-Klopp G.; Brauning R.; Williams J.L.; Stella A./titolo:SNPchiMp v.3: Integrating and standardizing single nucleotide polymorphism data for livestock species/doi:10.1186%2Fs12864-015-1497-1/rivista:BMC genomics/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume:16

Background: In recent years, the use of genomic information in livestock species for genetic improvement, association studies and many other fields has become routine. In order to accommodate different market requirements in terms of genotyping cost,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2cd134556f3285f4ed91545be5bdcc
https://hal.inrae.fr/hal-02631220

0692 Detection and selection against early embryonic lethals in United States beef breeds

Autor: Megan M Rolf, Brian Kinghorn, A. L. Van Eenennaam, Robert D. Schnabel, Barry Simpson, Michael D. MacNeil, D. S. Brown, D. J. Patterson, Jared E. Decker, Michael F. Smith, Jeremy F. Taylor

Publikováno v: Journal of Animal Science. 94:331-331

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82d573bc67518bc58bc97e18f38a2940
https://doi.org/10.2527/jam2016-0692