Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Barry Schweitzer"'
Autor:
Sarah Keasey, Christine Pugh, Alexander Tikhonov, Gengxin Chen, Barry Schweitzer, Aysegul Nalca, Robert G Ulrich
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15547 (2010)
Monkeypox is a zoonotic viral disease that occurs primarily in Central and West Africa. A recent outbreak in the United States heightened public health concerns for susceptible human populations. Vaccinating with vaccinia virus to prevent smallpox is
Externí odkaz:
https://doaj.org/article/9606b44ae0c64d1ca5d88c1b7c49e000
Autor:
James Meegan, Barry Schweitzer, Alexander P. Tikhonov, Patricio Tomas, Michael S. Lee, Michael Minto, Robert G. Ulrich, Sarah Keasey, Kara Schmid
Publikováno v:
Molecular & Cellular Proteomics : MCP
Antibodies provide a sensitive indicator of proteins displayed by bacteria during sepsis. Because signals produced by infection are naturally amplified during the antibody response, host immunity can be used to identify biomarkers for proteins that a
Publikováno v:
Current Opinion in Biotechnology. 16:447-452
Arrays of immobilized proteins have been developed for the discovery and characterization of protein functions ranging from molecular recognition to enzymatic activity. The success of these applications is highly dependent upon the maintenance of pro
Autor:
Barry Schweitzer, De Yang, Minjuan Wang, Joost J. Oppenheim, Helene F. Rosenberg, Stephen F. Kingsmore, O. M. Zack Howard, Qian Chen, Zhao Yuan Wang, Dianne L. Newton, Qin Fu, Velizar T. Tchernev, Susanna M. Rybak, Dhavalkumar D. Patel
Publikováno v:
The Journal of Immunology. 173:6134-6142
A number of mammalian antimicrobial proteins produced by neutrophils and cells of epithelial origin have chemotactic and activating effects on host cells, including cells of the immune system. Eosinophil granules contain an antimicrobial protein know
Autor:
James Xia, Heshu Huang, Linhua Fang, R. Murli Krishna, Lei Sun, Chang-Gong Liu, Jaymie Robin Sawyer, Girish Nallur, Barry Schweitzer, Chenghua Luo, Robert Marrero, Weiping Shao, Pamela E. Bechtel, Stephen F. Kingsmore, Steve Wiltshire, Melissa Ray
Publikováno v:
Biomedical Microdevices. 5:115-123
Microarrays are becoming the platform of choice for the analysis of complex genomes, transcriptomes and proteomes. For a number of applications, however, sample or analyte abundance constraints limit the usefulness of microarrays. Rolling circle ampl
Autor:
Harley R. Ferguson, Steven Wiltshire, Barry Schweitzer, Nancy Bogdan, Jane Montano, Warren Maltzman, Vanessa Wheeler, Yuriy Gusev, Arumugham Raghunathan, Stephen F. Kingsmore, Jason Sparkowski
Publikováno v:
The American Journal of Pathology. 159:63-69
Immunohistochemistry is a method that can provide complementary diagnostic and prognostic information to morphological observations and soluble assays. Sensitivity, specificity, or requirements for arduous sample preparation or signal amplification p
Autor:
Stephen F. Kingsmore, Barry Schweitzer
Publikováno v:
Current Opinion in Biotechnology. 12:21-27
Major recent advances in molecular amplification in the past year were initial validation of two new amplification technologies (rolling circle amplification and Invader), a significant increase in the number of molecular diagnostic assays, achieveme
Autor:
Barry Schweitzer, Paul M. Lizardi, Shawn O’Malley, Zhengrong Zhu, Steven Wiltshire, Kari Kukanskis, Stephen F. Kingsmore, Jeremy J. Lambert, David C. Ward
Publikováno v:
Proceedings of the National Academy of Sciences. 97:10113-10119
We describe an adaptation of the rolling circle amplification (RCA) reporter system for the detection of protein Ags, termed “immunoRCA.” In immunoRCA, an oligonucleotide primer is covalently attached to an Ab; thus, in the presence of circular D
Autor:
Matthew Foti, Kartik Keertikar, Gregory Tucker-Kellogg, Surat Kumar, Kevin H. Gardner, Barry Schweitzer
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 144:301-304
In the present study, we examine the effects of two nucleoside analogs on the structure and dynamics of self-complementary duplexes and model primer/template duplexes.
Publikováno v:
Biochemistry. 34:9235-9248
The antiviral compound 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG, Ganciclovir) is used clinically to treat cytomegaloviral infections in immunocompromised hosts and more recently is being investigated as a chemotherapeutic agent to be used in co