Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Barry S. Winkler"'
Autor:
Barry S, Winkler
Publikováno v:
Nature. 525(7569)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc48ee9ec627a02aca1167401aa719a3
https://pubmed.ncbi.nlm.nih.gov/26178951
https://pubmed.ncbi.nlm.nih.gov/26178951
Autor:
Barry S. Winkler, Dennis J. Goebel
Publikováno v:
Journal of Neurochemistry. 98:1732-1745
Recent reports have linked neuronal cell death by necrosis to poly(ADP-ribose) polymerase-1 (PARP-1) hyperactivation. It is believed that under stress, the activity of this enzyme is up-regulated, resulting in extensive poly(ADP-ribosyl)ation of nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28d39ebcf31185814d06e5c458b23fca
https://doi.org/10.1111/j.1471-4159.2006.04065.x
https://doi.org/10.1111/j.1471-4159.2006.04065.x
Publikováno v:
Investigative ophthalmology & visual science, 47(6), 2726-31. Association for Research in Vision and Ophthalmology Inc.
The idea that diabetic complications are linked to an increase in the activity of sorbitol dehydrogenase resulting in an increase in the intracellular concentration of NADH and an increase in the redox ratio of NADH-to-NAD+ was first proposed in 1993
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396c7573277549c9035ca721a889f0b8
https://doi.org/10.1167/iovs.06-0076
https://doi.org/10.1167/iovs.06-0076
Publikováno v:
Neurochemistry International. 45:311-320
Glucose has long been considered the substrate for energy metabolism in the retina. Recently, an alternative hypothesis (metabolic coupling) suggested that mitochondria in retinal neurons utilize preferentially the lactate produced specifically by M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a096422d379f1a14e49852c5930ce09
https://doi.org/10.1016/j.neuint.2003.08.017
https://doi.org/10.1016/j.neuint.2003.08.017
Publikováno v:
Journal of Neurochemistry. 89:514-525
We have investigated the dependence of the rate of lactic acid production on the rate of Na(+) entry in cultured transformed rat Muller cells and in normal and dystrophic (RCS) rat retinas that lack photoreceptors. To modulate the rate of Na(+) entry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b3996c2c866663baf63aa7df98d1f06
https://doi.org/10.1111/j.1471-4159.2004.02405.x
https://doi.org/10.1111/j.1471-4159.2004.02405.x
Publikováno v:
American Journal of Physiology-Cell Physiology. 273:C1480-C1486
The role of Na+-K+-2Cl−cotransport in ion and fluid transport of the corneal endothelium was examined by measuring changes in corneal hydration and uptake of86Rb by the endothelial cell layer. Isolated, intact rabbit corneas maintain normal hydrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2131b000121934b82398f670bf36869b
https://doi.org/10.1152/ajpcell.1997.273.5.c1480
https://doi.org/10.1152/ajpcell.1997.273.5.c1480
Publikováno v:
Experimental Eye Research. 64:683-692
The metabolic competence and histological integrity of the frog retina in vitro were evaluated as a function of the presence/absence of exogenous glucose and of oxygen tension. Dark- and light-adapted frog neural retinas were incubated for 1-8 hr at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a667e8faf71ebafaa96630aea22ba443
https://doi.org/10.1006/exer.1996.0281
https://doi.org/10.1006/exer.1996.0281
Publikováno v:
Progress in Retinal and Eye Research. 13:1-29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31c2f017a8ed23d96a607eeb5b27c42f
https://doi.org/10.1016/1350-9462(94)90003-5
https://doi.org/10.1016/1350-9462(94)90003-5
Autor:
Barry S. Winkler
Publikováno v:
Investigative ophthalmologyvisual science. 49(8)
It is 1 undisputed that glutathione (GSH) is an important cellular antioxidant. Although it is commonly believed that GSH is present in all retinal cells, several publications show that GSH is not immunologically detectable in outer segments of rod a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4b4ac01d3ff01c70479a7c1418ef28
https://pubmed.ncbi.nlm.nih.gov/18660422
https://pubmed.ncbi.nlm.nih.gov/18660422
Autor:
Barry S. Winkler
Publikováno v:
Nature. 525:321-321
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba9826301ee91e118439d98d9ab7a6de
https://doi.org/10.1038/525321f
https://doi.org/10.1038/525321f