Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Barry S Clements"'
Autor:
David G. Hancock, William Ditcham, Eleanor Ferguson, Yuliya V. Karpievitch, Stephen M. Stick, Grant W. Waterer, Barry S. Clements
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundCurrent treatments for respiratory infections are severely limited. Ethanol’s unique properties including antimicrobial, immunomodulatory, and surfactant-like activity make it a promising candidate treatment for respiratory infections if
Externí odkaz:
https://doaj.org/article/c51e8bdc15cf4f109ca1055ab2a86f0b
Autor:
Samantha A McLean, Anthony Kicic, Barry S Clements, Sarath Ranganathan, Oded Breuer, Luke W. Garratt, Daniel R. Laucirica, Rabindra Tirouvanziam, C. Schofield, Stephen M. Stick
Publikováno v:
Journal of Cystic Fibrosis. 20:941-948
Background: Neutrophil elastase is a significant risk factor for structural lung disease in cystic fibrosis, and Pseudomonas aeruginosa airway infection is linked with neutrophilic inflammation and substantial respiratory morbidity. We aimed to evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b060aced7ad0d60bad18b5510eabd87
https://doi.org/10.1016/j.jcf.2020.12.015
https://doi.org/10.1016/j.jcf.2020.12.015
Autor:
Sivagurunathan Sutharsan, Edward F McKone, Damian G Downey, Jamie Duckers, Gordon MacGregor, Elizabeth Tullis, Eva Van Braeckel, Claire E Wainwright, Danie Watson, Neil Ahluwalia, Bote G Bruinsma, Christopher Harris, Anna P Lam, Yiyue Lou, Samuel M Moskowitz, Simon Tian, Jason Yuan, David Waltz, Marcus A Mall, Paul Aurora, Stijn Verhulst, Michael Lorenz, Jobst Roehmel, Wolfgang Gleiber, Susanne Naehrig, Florian Stehling, Silke van Koningsbruggen-Rietschel, Rainald Fischer, Damian Downey, Charles Haworth, Julian Legg, Peter Barry, Rebecca Thursfield, Simon James Doe, Tom Hilliard, Edward F Nash, Nicholas John Withers, Daniel Peckham, Helen Louise Barr, Timothy Lee, Robert Gray, Francois Vermeulen, Eef Vanderhelst, Philip J Robinson, Daniel J Smith, Siobhain A Mulrennan, Barry S Clements, Peter Wark
Publikováno v:
VX18-445-109 study group 2021, ' Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week, multicentre, randomised, double-blind, active-controlled, phase 3b trial ', The Lancet. Respiratory medicine . https://doi.org/10.1016/S2213-2600(21)00454-9
BackgroundElexacaftor plus tezacaftor plus ivacaftor is a triple-combination cystic fibrosis transmembrane conductance regulator (CFTR) modulator regimen shown to be generally safe and efficacious in people with cystic fibrosis aged 12 years or older
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c34a7aa3d2d4d1a01b05a402f021fc
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85124502293
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85124502293
Autor:
David W. Reid, Helga Mikkelsen, Stephen M. Stick, Samantha Grogan, Ramaa Puvvadi, Lucy McCahon, Barry S Clements, William Ditcham, Iain Lamont
Publikováno v:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 20(2)
Background We tested if disrupting iron utilisation by P. aeruginosa by adding the Tris-buffered chelating agent CaEDTA to nebulised tobramycin would enhance bacterial clearance and improve lung function in CF patients. Methods In this double-blind,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ce9784931e96ccf9e2fda58a0b1e7d
https://pubmed.ncbi.nlm.nih.gov/33341406
https://pubmed.ncbi.nlm.nih.gov/33341406