Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Barry R. Campbell"'
Autor:
Kersten M. Small, Caryn Hampton, Loise Gichuru, Joseph J. Lynch, Xiaoli Ping, Ray Rosa, Richard Kennan, Jeffrey B. Madwed, Xiaolan Shen, Barry R. Campbell
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 84:93-101
Introduction Mouse transverse aortic constriction (TAC) is a widely-used model of pressure overload-induced heart failure. An intrinsic limitation of the model is variability in the response to pressure overload even when employing a standard severit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6727b68ed4cd0d8e428f81c3429ec1eb
https://doi.org/10.1016/j.vascn.2016.12.001
https://doi.org/10.1016/j.vascn.2016.12.001
Autor:
Barry R Campbell, Catherine D. G. Hines, Jeffrey L. Evelhoch, Weisheng Zhang, Manishkumar Patel, Wenping Li, Dinko Gonzalez Trotter
Publikováno v:
ILAR Journal
It is well understood that the biopharmaceutical industry must improve efficiency along the path from laboratory concept to commercial product. In vivo imaging is recognized as a useful method to provide biomarkers for target engagement, treatment re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f49fc58fd8027fc8f9eec37ede81c5
http://europepmc.org/articles/PMC5886324
http://europepmc.org/articles/PMC5886324
Publikováno v:
Circulation Research. 121
Heart failure with preserved ejection fraction (HFpEF) occurs in over 50% of total HF population today and is growing with no approved therapies today. A major challenge to the field is that truly representative experimental models of HFpEF do not ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba2d93037229aac68571c4b8c3689586
https://doi.org/10.1161/res.121.suppl_1.98a
https://doi.org/10.1161/res.121.suppl_1.98a
Autor:
Valdeci Da Cunha, Kersten M. Small, Shu-Yu Sun, Xiaoli Ping, Liming Yang, Xiaolan Shen, Barry R. Campbell, Shuqin Zheng, Xuening Hong, Huawei Zhao, Chin-hu Huang, Richard Kennan, Jeffrey Madwed
Publikováno v:
Circulation Research. 119
The absence of animal models displaying clinical phenotypes of HFpEF represents a challenge to the pharmaceutical industry in the hope of identifying novel treatments that would benefit patients with this syndrome. We, at Merck, examined the supracor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27a6e093779fe6586e3a207b197bada7
https://doi.org/10.1161/res.119.suppl_1.262
https://doi.org/10.1161/res.119.suppl_1.262
Autor:
Christopher Tong, Karim Azer, Matthew Walker, Barry R. Campbell, Michael C. Desiderio, Diane Shevell, Michelle Bunzel
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 15:287-296
Quantification of hemodynamics may be invaluable in a drug development setting. However, one of the challenges in the application of imaging technologies for compound screening purposes is the large volume of data in a short amount of time. This arti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3114f81ce9558de219cd5e5b9013f5df
https://doi.org/10.1016/j.jala.2009.12.002
https://doi.org/10.1016/j.jala.2009.12.002
Autor:
Craig Fancourt, Karim Azer, Matthew Walker, Yuzhuo Su, Michelle Bunzel, Barry R. Campbell, Jeffrey R. Sachs
Publikováno v:
ASME 2009 Summer Bioengineering Conference, Parts A and B.
The artery wall is compliant and stretches in response to the traveling pressure pulse generated by the contracting heart. The dynamics of this motion are known to convey important information about the health of the artery and cardio-vascular system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc82010eb5dcd2d0818fd408aac6ccc
https://doi.org/10.1115/sbc2009-206843
https://doi.org/10.1115/sbc2009-206843
Autor:
Christopher Tong, Jeffrey Saltzman, Kaijie Fang, Karim Azer, Michael J. Forrest, Kimberly Kempadoo, Jacquelynn J. Cook, Matthew Walker, Samuel D. Wright, Euan Macintyre, Richard Hargreaves, Barry R. Campbell
Publikováno v:
Atherosclerosis. 204(1)
Improved methods for non-invasive in vivo assessment are needed to guide development of animal models of atherosclerosis and to evaluate target engagement and in vivo efficacy of new drugs. Using novel 3D-micro-ultrasound technology, we developed and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb29129f57dbd5a419d2e0985341d2a2
https://pubmed.ncbi.nlm.nih.gov/19135672
https://pubmed.ncbi.nlm.nih.gov/19135672
Autor:
Barry R. Campbell
Publikováno v:
Proceedings of the ASIL Annual Meeting. 85:169-170
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f4974e2c95a76759d08a3c19e5c9c04
https://doi.org/10.1017/s0272503700091680
https://doi.org/10.1017/s0272503700091680
Autor:
Campbell BR; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Gonzalez Trotter D; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Hines CD; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Li W; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Patel M; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Zhang W; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Evelhoch JL; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania.
Publikováno v:
ILAR journal [ILAR J] 2016 Dec; Vol. 57 (2), pp. 212-220.