Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Barry R, Stripp"'
Autor:
Andrew K. Beppu, Juanjuan Zhao, Changfu Yao, Gianni Carraro, Edo Israely, Anna Lucia Coelho, Katherine Drake, Cory M. Hogaboam, William C. Parks, Jay K. Kolls, Barry R. Stripp
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Epithelial plasticity has been suggested in lungs of mice following genetic depletion of stem cells but is of unknown physiological relevance. Viral infection and chronic lung disease share similar pathological features of stem cell loss in
Externí odkaz:
https://doaj.org/article/9706ebfced8e45afb13ec6066322b3aa
Autor:
Jiurong Liang, Guanling Huang, Xue Liu, Ningshan Liu, Forough Taghavifar, Kristy Dai, Changfu Yao, Nan Deng, Yizhou Wang, Peter Chen, Cory Hogaboam, Barry R Stripp, William C Parks, Paul W Noble, Dianhua Jiang
Publikováno v:
eLife, Vol 12 (2023)
Aging is a critical risk factor in idiopathic pulmonary fibrosis (IPF). Dysfunction and loss of type 2 alveolar epithelial cells (AEC2s) with failed regeneration is a seminal causal event in the pathogenesis of IPF, although the precise mechanisms fo
Externí odkaz:
https://doaj.org/article/dc36e141f9de42bfa03fa5b279b8212e
Autor:
Konstantinos-Dionysios Alysandratos, Carolina Garcia-de-Alba, Changfu Yao, Patrizia Pessina, Jessie Huang, Carlos Villacorta-Martin, Olivia T. Hix, Kasey Minakin, Claire L. Burgess, Pushpinder Bawa, Aditi Murthy, Bindu Konda, Michael F. Beers, Barry R. Stripp, Carla F. Kim, Darrell N. Kotton
Publikováno v:
JCI Insight, Vol 8, Iss 1 (2023)
Dysfunction of alveolar epithelial type 2 cells (AEC2s), the facultative progenitors of lung alveoli, is implicated in pulmonary disease pathogenesis, highlighting the importance of human in vitro models. However, AEC2-like cells in culture have yet
Externí odkaz:
https://doaj.org/article/f25a0ef19189460ebd6f7a2ad18d270c
Autor:
Moumita Ghosh, Cynthia L. Hill, Alfahdah Alsudayri, Scott W. Lallier, Don Hayes Jr., Saranga Wijeratne, Zhang Hong Tan, Tendy Chiang, John E. Mahoney, Gianni Carraro, Barry R. Stripp, Susan D. Reynolds
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 12, Pp 1696-1713 (2021)
Abstract Chronic lung disease has been attributed to stem cell aging and/or exhaustion. We investigated these mechanisms using mouse and human tracheobronchial tissue‐specific stem cells (TSC). In mouse, chromatin labeling and flow cytometry demons
Externí odkaz:
https://doaj.org/article/9d6a17e6e3c24ef9bf31f1af6b2661cd
Autor:
Gantsetseg Tumurkhuu, Duygu Ercan Laguna, Richard E. Moore, Jorge Contreras, Gabriela De Los Santos, Luisa Akaveka, Erica N. Montano, Yizhou Wang, Mariko Ishimori, Swamy Venuturupalli, Lindsy J. Forbess, Barry R. Stripp, Daniel J. Wallace, Caroline A. Jefferies
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Diffuse alveolar hemorrhage (DAH), although rare, is a life-threatening complication of systemic lupus erythematosus (SLE). Little is known about the pathophysiology of DAH in humans, although increasingly neutrophils, NETosis and inflammatory monocy
Externí odkaz:
https://doaj.org/article/16d6495b0a4a4ec9b252b49043fdb93d
Autor:
Peter G. Boone, Lauren K. Rochelle, Joshua D. Ginzel, Veronica Lubkov, Wendy L. Roberts, P. J. Nicholls, Cheryl Bock, Mei Lang Flowers, Richard J. von Furstenberg, Barry R. Stripp, Pankaj Agarwal, Alexander D. Borowsky, Robert D. Cardiff, Larry S. Barak, Marc G. Caron, H. Kim Lyerly, Joshua C. Snyder
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Pre-malignant cells harbouring oncogenic mutations can populate and spread throughout a tissue. Here, using a rainbow mouse system, the authors explore how clonal expansion in the mouse intestine might explain high levels of intra-tumoural heterogene
Externí odkaz:
https://doaj.org/article/757eeb180b694b92bb92c9f6266b5ea1
Autor:
Tingting Yuan, Thomas Volckaert, Elizabeth F. Redente, Seantel Hopkins, Kylie Klinkhammer, Roxana Wasnick, Cho-Ming Chao, Jie Yuan, Jin-San Zhang, Changfu Yao, Susan Majka, Barry R. Stripp, Andreas Günther, David W.H. Riches, Saverio Bellusci, Victor J. Thannickal, Stijn P. De Langhe
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 1041-1055 (2019)
Summary: Idiopathic pulmonary fibrosis is a common form of interstitial lung disease resulting in alveolar remodeling and progressive loss of pulmonary function because of chronic alveolar injury and failure to regenerate the respiratory epithelium.
Externí odkaz:
https://doaj.org/article/fcba214ffea4484dac67b28149cb14a9
Autor:
Xue Liu, Simon C. Rowan, Jiurong Liang, Changfu Yao, Guanling Huang, Nan Deng, Ting Xie, Di Wu, Yizhou Wang, Ankita Burman, Tanyalak Parimon, Zea Borok, Peter Chen, William C. Parks, Cory M. Hogaboam, S. Samuel Weigt, John Belperio, Barry R. Stripp, Paul W. Noble, Dianhua Jiang
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102551- (2021)
Summary: Pulmonary mesenchymal cells are critical players in both the mouse and human during lung development and disease states. They are increasingly recognized as highly heterogeneous, but there is no consensus on subpopulations or discriminative
Externí odkaz:
https://doaj.org/article/61fae4523109433c93b49fa80896a3e0
Autor:
Apoorva Mulay, Bindu Konda, Gustavo Garcia, Jr., Changfu Yao, Stephen Beil, Jaquelyn M. Villalba, Colin Koziol, Chandani Sen, Arunima Purkayastha, Jay. K. Kolls, Derek A. Pociask, Patrizia Pessina, Julio Sainz de Aja, Carolina Garcia-de-Alba, Carla F. Kim, Brigitte Gomperts, Vaithilingaraja Arumugaswami, Barry R. Stripp
Publikováno v:
Cell Reports, Vol 35, Iss 5, Pp 109055- (2021)
Summary: Coronavirus disease 2019 (COVID-19) is the latest respiratory pandemic caused by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2). Although infection initiates in the proximal airways, severe and sometimes fatal symptoms
Externí odkaz:
https://doaj.org/article/c6b335eff48e42068ebd55ba5f9b3751
Autor:
Changfu Yao, Stephanie A. Bora, Tanyalak Parimon, Tanzira Zaman, Oren A. Friedman, Joseph A. Palatinus, Nirmala S. Surapaneni, Yuri P. Matusov, Giuliana Cerro Chiang, Alexander G. Kassar, Nayan Patel, Chelsi E.R. Green, Adam W. Aziz, Harshpreet Suri, Jo Suda, Andres A. Lopez, Gislâine A. Martins, Barry R. Stripp, Sina A. Gharib, Helen S. Goodridge, Peter Chen
Publikováno v:
Cell Reports, Vol 34, Iss 13, Pp 108943- (2021)
Externí odkaz:
https://doaj.org/article/d1095ed61182462a817f5dee782da1c7