Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Barry P. Simmons"'
Autor:
Fumitaka Mizoguchi, Kamil Slowikowski, Kevin Wei, Jennifer L. Marshall, Deepak A. Rao, Sook Kyung Chang, Hung N. Nguyen, Erika H. Noss, Jason D. Turner, Brandon E. Earp, Philip E. Blazar, John Wright, Barry P. Simmons, Laura T. Donlin, George D. Kalliolias, Susan M. Goodman, Vivian P. Bykerk, Lionel B. Ivashkiv, James A. Lederer, Nir Hacohen, Peter A. Nigrovic, Andrew Filer, Christopher D. Buckley, Soumya Raychaudhuri, Michael B. Brenner
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Synovial fibroblasts are thought to be central mediators of joint destruction in rheumatoid arthritis (RA). Here the authors use single-cell transcriptomics and flow cytometry to identify synovial fibroblast subsets that are expanded and display dist
Externí odkaz:
https://doaj.org/article/c5ce4a229b2441f988b5517aa170745b
Autor:
Tamara D. Rozental, Brandon E. Earp, Jason Fanuele, Ariana N. Mora, Barry P. Simmons, Lauren Adey, Alfred V. Hess, John Z. Zhao, Michael J. Garcia, Eon K. Shin, David E. Ruchelsman, Jeffrey D. Stone, Philip E. Blazar
Publikováno v:
Journal of Hand Surgery Global Online, Vol 1, Iss 3, Pp 161-165 (2019)
Purpose: Collagenase Clostridium histolyticum (CCH) has increasingly been used to treat Dupuytren contracture since its Food and Drug Administration approval in 2010. One concern among practitioners is the learning curve of this new technique. This s
Autor:
Barry P. Simmons, Dafang Zhang
Publikováno v:
Principles of Orthopedic Practice for Primary Care Providers ISBN: 9783030746247
Arthritic conditions of the hand and wrist are common in our aging population. We discuss the diagnosis and management of osteoarthritis, post-traumatic arthritis, and rheumatoid arthritis that affect the hand and wrist. In the hand, primary osteoart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a174a7c3f041fe6ce2af6f3771ad220
https://doi.org/10.1007/978-3-030-74625-4_18
https://doi.org/10.1007/978-3-030-74625-4_18
Publikováno v:
Hand (N Y)
Background: Silastic metacarpophalangeal arthroplasty (SMPA) has proven to be a durable option for end-stage arthritis in the non-thumb digits, while fusion has been the mainstay procedure for the thumb metacarpophalangeal joint (MP). Few studies exi
Publikováno v:
The Journal of the American Academy of Orthopaedic Surgeons. 27(21)
Since the advent of disease-modifying antirheumatic drugs for rheumatoid arthritis, orthopedic surgeons see fewer patients in the office who require hand surgery. However, a significant number of patients still seek surgical intervention to improve p
Autor:
Sook Kyung Chang, Laura T. Donlin, George D. Kalliolias, Barry P. Simmons, Fumitaka Mizoguchi, Kamil Slowikowski, Philip E. Blazar, Brandon E. Earp, Vivian P. Bykerk, Michael B. Brenner, Christopher D. Buckley, James A. Lederer, Peter A. Nigrovic, Jason D. Turner, Soumya Raychaudhuri, Erika H. Noss, Susan M. Goodman, Jennifer L. Marshall, Kevin Wei, Nir Hacohen, Andrew Filer, Deepak A. Rao, John Wright, Hung N. Nguyen, Lionel B. Ivashkiv
Publikováno v:
Nature Communications
Mizoguchi, F, Slowikowski, K, Wei, K, Marshall, J L, Rao, D A, Chang, S K, Nguyen, H N, Noss, E H, Turner, J D, Earp, B E, Blazar, P E, Wright, J, Simmons, B P, Donlin, L T, Kalliolias, G D, Goodman, S M, Bykerk, V P, Ivashkiv, L B, Lederer, J A, Hacohen, N, Nigrovic, P A, Filer, A, Buckley, C D, Raychaudhuri, S & Brenner, M B 2018, ' Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis ', Nature Communications, vol. 9, no. 1, 789 . https://doi.org/10.1038/s41467-018-02892-y
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Mizoguchi, F, Slowikowski, K, Wei, K, Marshall, J L, Rao, D A, Chang, S K, Nguyen, H N, Noss, E H, Turner, J D, Earp, B E, Blazar, P E, Wright, J, Simmons, B P, Donlin, L T, Kalliolias, G D, Goodman, S M, Bykerk, V P, Ivashkiv, L B, Lederer, J A, Hacohen, N, Nigrovic, P A, Filer, A, Buckley, C D, Raychaudhuri, S & Brenner, M B 2018, ' Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis ', Nature Communications, vol. 9, no. 1, 789 . https://doi.org/10.1038/s41467-018-02892-y
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Fibroblasts regulate tissue homeostasis, coordinate inflammatory responses, and mediate tissue damage. In rheumatoid arthritis (RA), synovial fibroblasts maintain chronic inflammation which leads to joint destruction. Little is known about fibroblast
Autor:
Beverlie L. Ting, Barry P. Simmons
Publikováno v:
Principles of Orthopedic Practice for Primary Care Providers ISBN: 9783319686608
Osteoarthritic conditions of the hand and wrist are common in our aging population. We discuss the diagnosis and management of both primary and secondary osteoarthritic conditions that affect the hand and wrist. In the hand, primary osteoarthritis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa99ea89b29ae87ebc594326f32d6e2c
https://doi.org/10.1007/978-3-319-68661-5_14
https://doi.org/10.1007/978-3-319-68661-5_14
Autor:
Fumitaka Mizoguchi, Philip E. Blazar, Kamil Slowikowski, Christopher D. Buckley, Laura T. Donlin, Sook Kyung Chang, George D. Kalliolias, Lionel B. Ivashkiv, Jennifer L. Marshall, Kevin Wei, Brandon E. Earp, Michael B. Brenner, Vivian P. Bykerk, James A. Lederer, Peter A. Nigrovic, Barry P. Simmons, Jason D. Turner, Soumya Raychaudhuri, Nir Hacohen, Susan M. Goodman, Erika H. Noss, Deepak A. Rao, Hung N. Nguyen, Andrew Filer, John Wright
Fibroblasts mediate normal tissue matrix remodeling, but they can cause fibrosis or tissue destruction following chronic inflammation. In rheumatoid arthritis (RA), synovial fibroblasts expand, degrade cartilage, and drive joint inflammation. Little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3996337870fd4d432a70c0bd3d61451f
https://doi.org/10.1101/126193
https://doi.org/10.1101/126193
Autor:
Maya J. BenBarak, John A. Wright, Wolfgang Hueber, Christophe Benoist, William H. Robinson, Diane Mathis, Marc Monestier, Hidde L. Ploegh, Thomas S. Thornhill, Benedikt M. Kessler, Beren H. Tomooka, Barry P. Simmons, Paul A. Monach
Publikováno v:
Proceedings of the National Academy of Sciences. 106:15867-15872
Deposits of Ig and complement are abundant in affected joints of patients with rheumatoid arthritis (RA) and in animal models of RA in which antibodies are demonstrably pathogenic. To identify molecular targets of the Igs deposited in arthritic joint
Publikováno v:
Techniques in Hand & Upper Extremity Surgery. 12:38-42
The first carpometacarpal (CMC) joint, also referred to as trapeziometacarpal joint, is the area of the hand most commonly symptomatic of osteoarthritis. Although there are a variety of surgical techniques that treat this condition, this article focu