Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Barry N Hudspith"'
Autor:
Adele Costabile, Sara Santarelli, Sandrine P Claus, Jeremy Sanderson, Barry N Hudspith, Jonathan Brostoff, Jane L Ward, Alison Lovegrove, Peter R Shewry, Hannah E Jones, Andrew M Whitley, Glenn R Gibson
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111225 (2014)
A variety of foods have been implicated in symptoms of patients with Irritable Bowel Syndrome (IBS) but wheat products are most frequently cited by patients as a trigger. Our aim was to investigate the effects of breads, which were fermented for diff
Externí odkaz:
https://doaj.org/article/f73a9f98992144728bc5fd46c0ccc12e
Autor:
Natalie J. Prescott, Liljana Petrovska, John Hermon-Taylor, Alex Boussioutas, Tim Elliott, Barry N. Hudspith, Jonathan Brostoff, Christopher G. Mathew, Neil B. Rayment, Jeremy D. Sanderson
Publikováno v:
Journal of Gastroenterology and Hepatology. 30:1265-1274
Background and Aim Escherichia coli can be isolated from lamina propria macrophages in Crohn's disease (CD), and their intramacrophage persistence may provide a stimulus for inflammation. To further determine the contributions of macrophage dysfuncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37315d0e1e5a297df0bb6549e45cc3ad
https://doi.org/10.1111/jgh.12955
https://doi.org/10.1111/jgh.12955
Autor:
Jonathan Brostoff, Barry N. Hudspith, Gareth Parkes, Liljana Petrovska, Kevin Whelan, Miranda Lomer, Neil B. Rayment, Jeremy D. Sanderson
Publikováno v:
Neurogastroenterology & Motility. 24:31-39
Background There is increasing evidence to support a role for the gastrointestinal microbiota in the etiology of irritable bowel syndrome (IBS). Given the evidence of an inflammatory component to IBS, the mucosa-associated microbiota potentially play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d31addc51b6ff80c80bbb547a8d89ee
https://doi.org/10.1111/j.1365-2982.2011.01803.x
https://doi.org/10.1111/j.1365-2982.2011.01803.x
Autor:
Katarzyna Blaszczyk, Naoya Hosono, Ni Huang, Matthew E. Hurles, Christopher G. Mathew, Alastair Forbes, Yusuke Nakamura, Sheila A. Fisher, Cathryn M. Lewis, Clive M. Onnie, Barbara E. Stranger, Michiaki Kubo, Richard Redon, Keiko Yamazaki, Emmanouil T. Dermitzakis, Jeremy D. Sanderson, Gareth Parkes, John C. Mansfield, Katherine M. Dominy, Roland G. Roberts, Barry N. Hudspith, Natalie J. Prescott
Publikováno v:
Human Molecular Genetics, Vol. 19, No 9 (2010) pp. 1828-1839
Human Molecular Genetics
Human Molecular Genetics
DNA polymorphisms in a region on chromosome 5q33.1 which contains two genes, immunity related GTPase related family, M (IRGM) and zinc finger protein 300 (ZNF300), are associated with Crohn's disease (CD). The deleted allele of a 20 kb copy number va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6c70b5569394217bb1b9dec382dfa2
https://doi.org/10.1093/hmg/ddq041
https://doi.org/10.1093/hmg/ddq041
Autor:
Christopher G. Mathew, John Hermon-Taylor, Rebecca Hands, Tim Elliott, Alex Boussioutas, Natalie J. Prescott, Stephen A. Bustin, Liljana Petrovska, Jonathan Brostoff, Kirstin M. Taylor, Gareth Parkes, Neil B. Rayment, Barry N. Hudspith, Jeremy D. Sanderson
Publikováno v:
BMC Gastroenterology
Background Abnormal handling of E. coli by lamina propria (LP) macrophages may contribute to Crohn’s disease (CD) pathogenesis. We aimed to determine LP macrophage phenotypes in CD, ulcerative colitis (UC) and healthy controls (HC), and in CD, to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0afc7df5cf452c99ae2f50c6b274227
https://doi.org/10.1186/s12876-015-0305-3
https://doi.org/10.1186/s12876-015-0305-3
Autor:
Hannah Jones, Glenn R. Gibson, Sara Santarelli, Peter R. Shewry, Jane L. Ward, Adele Costabile, Andrew M. Whitley, Jonathan Brostoff, Barry N. Hudspith, Jeremy D. Sanderson, Alison Lovegrove, Sandrine P. Claus
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111225 (2014)
Costabile, A, Santarelli, S, Claus, S P, Sanderson, J, Hudspith, B N, Brostoff, J, Ward, J L, Lovegrove, A, Shewry, P R, Jones, H E, Whitley, A M & Gibson, G R 2014, ' Effect of breadmaking process on in vitrogut microbiota parameters in irritable bowel syndrome ', PL o S One, vol. 9, no. 10, e111225 . https://doi.org/10.1371/journal.pone.0111225
PLoS ONE
Costabile, A, Santarelli, S, Claus, S P, Sanderson, J, Hudspith, B N, Brostoff, J, Ward, J L, Lovegrove, A, Shewry, P R, Jones, H E, Whitley, A M & Gibson, G R 2014, ' Effect of breadmaking process on in vitrogut microbiota parameters in irritable bowel syndrome ', PL o S One, vol. 9, no. 10, e111225 . https://doi.org/10.1371/journal.pone.0111225
PLoS ONE
A variety of foods have been implicated in symptoms of patients with Irritable Bowel Syndrome (IBS) but wheat products are most frequently cited by patients as a trigger. Our aim was to investigate the effects of breads, which were fermented for diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f105767abb48dfa6aed6c5122a76af58
http://europepmc.org/articles/PMC4214745?pdf=render
http://europepmc.org/articles/PMC4214745?pdf=render
Publikováno v:
Environmental Health Perspectives
We have attempted to address the requirements necessary for alveolar macrophage accessory cell function. We have also examined the in vitro and in vivo factors that must be taken into account when interpreting results from experimental studies. Diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6873050b11336eb10db136b4926a375
http://europepmc.org/articles/PMC1519529
http://europepmc.org/articles/PMC1519529
Autor:
M Michael, G L Green, Barry N. Hudspith, Jeremy D. Sanderson, Neil B. Rayment, Jonathan Brostoff, David S. Rampton, Kenneth D. Bruce, N Staines, M Mylonaki
Publikováno v:
Journal of applied microbiology. 100(3)
Aims: To study large intestinal mucosal bacterial communities by Denaturing Gradient Gel Electrophoresis (DGGE) profiling and sequencing of 16S rRNA gene polymerase chain reaction (PCR) products amplified from DNA extracted from colorectal biopsies t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125f10c372e2091adbd20981f6cbe80e
https://pubmed.ncbi.nlm.nih.gov/16478485
https://pubmed.ncbi.nlm.nih.gov/16478485
Autor:
Anthony Graham Wynne, Glenn R. Gibson, Barry N. Hudspith, Anne L. McCartney, Jonathan Brostoff
Publikováno v:
Anaerobe. 10(3)
Chemostat culture was used to determine the effects of the antimicrobial agents tetracycline and nystatin on predominant components of the human gut microflora. Their addition to mixed culture systems caused a non-specific, and variable, decrease in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a852694a70027997aaf0f7ea89ebc3e4
https://pubmed.ncbi.nlm.nih.gov/16701514
https://pubmed.ncbi.nlm.nih.gov/16701514
Autor:
Neil B. Rayment, Tracey Elliott, R. Linedale, Jeremy D. Sanderson, Barry N. Hudspith, John Hermon-Taylor, Tim J. Bull
Publikováno v:
Gut. 60:A142-A143
Introduction Abnormal intestinal macrophage function which could allow persistence of candidate bacterial triggering agents such as E coli and Mycobacterium avium subspecies paratuberculosis (MAP), has been implicated in the pathogenesis of Crohn9s d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4068935dbe0661bd51a4168a9f7cb5
https://doi.org/10.1136/gut.2011.239301.302
https://doi.org/10.1136/gut.2011.239301.302