Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Barry M. Markaverich"'
Autor:
Trellis Thompson, Jan R. Crowley, John Turk, Barry M. Markaverich, Mary Ann Rodriguez, Kevin Shoulars
Publikováno v:
Cancer Letters. 264:265-273
THF-diols (9,12-oxy-10,13-dihydroxyoctadecanoic and 10,13-oxy-9,12-dihydroxyoctadecanoic acids) are endocrine disrupters in rats and mitogens in breast cancer cells. Microarray analyses and real-time PCR analyses on RNA from THF-treated MCF-7 cells r
Publikováno v:
Environmental Health Perspectives
Background We characterized an endocrine disruptor from ground corncob bedding material that interferes with male and female sexual behavior and ovarian cyclicity in rats and stimulates estrogen receptor (ER)-positive and ER-negative breast cancer ce
Autor:
Shaila K. Mani, Barry M. Markaverich, Jan R. Crowley, John Turk, Andrea Reyna, Trellis Thompson, John T. Sharp, Mary Alejandro, Wendy Portillo
Publikováno v:
Environmental Health Perspectives
Reports from our laboratory and others have described adverse effects of corncob bedding on reproductive function in rats and mice (Markaverich et al. 2002b; Port and Kaltenbach 1969). For this reason, we recently identified one class of biological a
Publikováno v:
Steroids. 71:865-874
These studies assessed the effects of 3,4-dihydroxybenzalacetone (ZN-1) and 1-(3,4-dihydroxyphenyl)-2-propanol (ZN-2) on MCF-7 cell proliferation. The compounds blocked [3H]estradiol binding to nuclear type II sites, but did not compete for [3H]estra
Publikováno v:
Steroids. 70:750-754
The mitogenic agent that disrupts male and female sexual behavior has been isolated from corncob bedding. The disrupting activity resides in an isomeric mixture of linoleic acid derivatives with a tetrahydrofuran ring and two hydroxyl groups (THF-dio
Autor:
Andrea Reyna, Barry M. Markaverich, Mary Alejandro, Nancy Casajuna, John T. Sharp, Jan R. Crowley, Shaila K. Mani, Kevin Shoulars
Publikováno v:
Environmental Health Perspectives
Previous studies in our laboratory demonstrated that high-performance liquid chromatography (HPLC) analysis of ground corncob bedding extracts characterized two components (peak I and peak II) that disrupted endocrine function in male and female rats
Autor:
Trellis Thompson, Kevin Shoulars, John Turk, Mary Ann Rodrigues, Jan R. Crowley, Barry M. Markaverich
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 96:19-30
[ 3 H]luteolin covalently labels two forms (11 kDa and 35 kDa proteins) of type II binding sites in rat uterine nuclear extracts [K. Shoulars, T. Brown, M. Alejandro, J. Crowley, B. Markaverich, Identification of rat uterine nuclear type II [ 3 H]est
Publikováno v:
Biochemical and Biophysical Research Communications. 296:1083-1090
[3H]Luteolin binds covalently to uterine nuclear type II sites [B. Markaverich, K. Shoulars, M.A. Alejandro, T. Brown, Steroids 66 (2001) 707] and was used to identify this protein(s). SDS–PAGE analyses of [3H]luteolin-labeled type II site preparat
Autor:
John Turk, Jan R. Crowley, David Markaverich, Barry M. Markaverich, Lois Zitzow, Nancy Casajuna, Nathan Camarao, Robert E. Faith, Mary Alejandro, Jamal Hill, Ken Bhirdo
Publikováno v:
Biochemical and Biophysical Research Communications. 291:692-700
A mitogenic agent in corncob bedding and fresh corn products disrupts sexual behavior and estrous cyclicity in rats. The mitogenic activity resides in an isomeric mixture of linoleic acid derivatives with a tetrahydrofuran ring and two hydroxyl group
Autor:
Robert E. Faith, Andrea Mitchell, Chris Murchison, Mary Alejandro, Barry M. Markaverich, Shaila K. Mani, Trellis Brown, Claudia Velez-Trippe, Bert W. O'Malley, David Markaverich
Publikováno v:
Environmental Health Perspectives. 110:169-177
Housing adult rats on ground corncob bedding impedes male and female mating behavior and causes acyclicity in females. The suppressive effects on ovarian cyclicity are mimicked by a mitogenic agent purified from the ground corncob bedding material (c