Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Barry J. A. Laird"'
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Akademický článek
Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series
Autor: James McDonald, Judith Sayers, Stefan D. Anker, Jann Arends, Trude Rakel Balstad, Vickie Baracos, Leo Brown, Asta Bye, Olav Dajani, Ross Dolan, Marie T. Fallon, Eilidh Fraser, Christine Griel, Aleksandra Grzyb, Marianne Hjermstad, Mariam Jamal‐Hanjani, Gunnhild Jakobsen, Stein Kaasa, Donald McMillan, Matthew Maddocks, Iain Philips, Inger O. Ottestad, Kieran F. Reid, Mariana S. Sousa, Melanie R. Simpson, Ola Magne Vagnildhaug, Richard J. E. Skipworth, Tora S. Solheim, Barry J. A. Laird, the Cancer Cachexia Endpoints Working Group
Publikováno v: Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 5, Pp 1932-1948 (2023)
Abstract In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, it is not clear
Externí odkaz: https://doaj.org/article/631dce5bbeae444e8aa791e121b8775f
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2
Akademický článek
Power Comparisons and Clinical Meaning of Outcome Measures in Assessing Treatment Effect in Cancer Cachexia: Secondary Analysis From a Randomized Pilot Multimodal Intervention Trial
Autor: Trude R. Balstad, Cinzia Brunelli, Caroline H. Pettersen, Svanhild A. Schønberg, Frank Skorpen, Marie Fallon, Stein Kaasa, Asta Bye, Barry J. A. Laird, Guro B. Stene, Tora S. Solheim
Publikováno v: Frontiers in Nutrition, Vol 7 (2021)
Background: New clinical trials in cancer cachexia are essential, and outcome measures with high responsiveness to detect meaningful changes are crucial. This secondary analysis from a multimodal intervention trial estimates sensitivity to change and
Externí odkaz: https://doaj.org/article/69fd1285aeae4e61abcc6630e57d4633
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3
Akademický článek
REVOLUTION (Routine EValuatiOn of people LivIng with caNcer)-Protocol for a prospective characterisation study of patients with incurable cancer.
Autor: Rebekah Patton, Jane Cook, Erna Haraldsdottir, Duncan Brown, Ross D Dolan, Donald C McMillan, Richard J E Skipworth, Marie Fallon, Barry J A Laird
Publikováno v: PLoS ONE, Vol 16, Iss 12, p e0261175 (2021)
IntroductionThere is a pressing need for a holistic characterisation of people with incurable cancer. In this group, where quality of life and improvement of symptoms are therapeutic priorities, the physical and biochemical manifestations of cancer a
Externí odkaz: https://doaj.org/article/e1284e739dcb4025b3787e9c83093a76
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4
The impact of acute systemic inflammation secondary to oesophagectomy and anastomotic leak on computed tomography body composition analyses
Autor: Leo R. Brown, Michael I. Ramage, Ross D. Dolan, Judith Sayers, Nikki Bruce, Lachlan Dick, Sharukh Sami, Donald C. McMillan, Barry J. A. Laird, Stephen J. Wigmore, Richard J. E. Skipworth
Publikováno v: Brown, L, Ramage, M I, Dolan, R, Sayers, J, Bruce, N, Dick, L, Sami, S, McMillan, D, Laird, B J A, Wigmore, S J & Skipworth, R J E 2023, ' The impact of acute systemic inflammation secondary to oesophagectomy and anastomotic leak on computed tomography body composition analyses ', Cancers, vol. 15, no. 9, 2577 . https://doi.org/10.3390/cancers15092577
Cancers; Volume 15; Issue 9; Pages: 2577
This study aimed to longitudinally assess CT body composition analyses in patients who experienced anastomotic leak post-oesophagectomy. Consecutive patients, between 1 January 2012 and 1 January 2022 were identified from a prospectively maintained d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f344b0b3d7a2b788fc437298e4396699
https://www.pure.ed.ac.uk/ws/files/347635940/cancers_15_02577_v2.pdf
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5
Understanding Cancer Cachexia and Its Implications in Upper Gastrointestinal Cancers
Autor: Leo R. Brown, Barry J. A. Laird, Stephen J. Wigmore, Richard J. E. Skipworth
Publikováno v: Brown, L, Laird, B J A, Wigmore, S J & Skipworth, R J E 2022, ' Understanding Cancer Cachexia and Its Implications in Upper Gastrointestinal Cancers ', Current treatment options in oncology . https://doi.org/10.1007/s11864-022-01028-1
Opinion statementConsiderable advances in the investigation and management of oesophagogastric cancer have occurred over the last few decades. While the historically dismal prognosis associated with these diseases has improved, outcomes remain very p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccfa244e2701bdc5bd43ddbbf2be252
https://pubmed.ncbi.nlm.nih.gov/36269458
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6
Randomized Double-Blind Trial of Pregabalin Versus Placebo in Conjunction With Palliative Radiotherapy for Cancer-Induced Bone Pain
Autor: Marie, Fallon, Peter J, Hoskin, Lesley A, Colvin, Susan M, Fleetwood-Walker, Douglas, Adamson, Anthony, Byrne, Gordon D, Murray, Barry J A, Laird
Publikováno v: Journal of Clinical Oncology
Fallon, M, Hoskin, P J, Colvin, L A, Fleetwood-Walker, S M, Adamson, D, Byrne, A, Murray, G D & Laird, B J A 2016, ' Randomized Double-Blind Trial of Pregabalin Versus Placebo in Conjunction With Palliative Radiotherapy for Cancer-Induced Bone Pain ', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 34, no. 6, pp. 550-6 . https://doi.org/10.1200/JCO.2015.63.8221
Fallon, M, Hoskin, P J, Colvin, L A, Fleetwood-Walker, S M, Adamson, D, Byrne, A, Murray, G D & Laird, B J A 2016, ' Randomized Double-Blind Trial of Pregabalin Versus Placebo in Conjunction With Palliative Radiotherapy for Cancer-Induced Bone Pain ', Journal of Clinical Oncology, vol. 34, no. 6, pp. 550-556 . https://doi.org/10.1200/JCO.2015.63.8221
Purpose\ud \ud \ud Cancer-induced bone pain (CIBP) affects one third of patients with cancer. Radiotherapy remains the gold-standard treatment; however, laboratory and clinical work suggest that pregabalin may be useful in treating CIBP. The aim of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::34a56697b283d9855b8e22fe0b4d9deb
http://europepmc.org/articles/PMC5098845
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