Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Barry G. Garchow"'
Publikováno v:
Mol Immunol
Systemic lupus erythematosus (SLE, lupus) is a chronic autoimmune disease characterized by loss of peripheral tolerance to nuclear self-antigens. It is increasingly recognized that aberrant T cell metabolism is a critical mediator of SLE immunopathol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a161e9e5f82394c7bf5b2e9825e0abba
https://europepmc.org/articles/PMC8026684/
https://europepmc.org/articles/PMC8026684/
Autor:
Barry G. Garchow, Chun-Hao Chiu, Scott L. Diamond, Grace S. Tan, Marianthi Kiriakidou, David Metzler
Publikováno v:
ACS Chemical Biology
Argonaute proteins are the core components of the microRNP/RISC. The biogenesis and function of microRNAs and endo- and exo- siRNAs are regulated by Ago2, an Argonaute protein with RNA binding and nuclease activities. Currently, there are no in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc9a09c5ac4b296e3574bfd1aaaa00e
https://doi.org/10.1021/cb200253h
https://doi.org/10.1021/cb200253h
Autor:
John P. Morris, Xuhang Liu, Marianthi Kiriakidou, Grace S. Tan, Trinna L. Cuellar, Michael T. McManus, Barry G. Garchow, Jennifer Yeung
Publikováno v:
Nucleic Acids Research
Mammalian Argonaute 2 (Ago2) protein associates with microRNAs (miRNAs) or small interfering RNAs (siRNAs) forming RNA-induced silencing complexes (RISCs/miRNPs). In the present work, we characterize the RNA-binding and nucleolytic activity of recomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4d688a0b66a6f4aafcae57a01e4cda
https://doi.org/10.1093/nar/gkp812
https://doi.org/10.1093/nar/gkp812
Autor:
Marianthi Kiriakidou, Barry G. Garchow
Publikováno v:
Clinical immunology (Orlando, Fla.). 162
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression primarily at the post-transcriptional level. Emerging evidence supports a regulatory role for miRNAs in the immune response and autoimmunity. In this work, we investigated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c81c018b1ca8c8cb6b176ec402c1b7
https://pubmed.ncbi.nlm.nih.gov/26631756
https://pubmed.ncbi.nlm.nih.gov/26631756
Publikováno v:
Archives of Biochemistry and Biophysics. 440:133-140
Phytases catalyze the hydrolysis of phytic acid (InsP6, myo-inositol hexakisphosphate), the most abundant inositol phosphate in cells. In cereal grains and legumes, it constitutes 3-5% of the dry weight of seeds. The inability of humans and monogastr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3837464302a8d53e400e7f1dfa6e968a
https://doi.org/10.1016/j.abb.2005.05.029
https://doi.org/10.1016/j.abb.2005.05.029
Autor:
Patricia Y. Tsao, Marianthi Kiriakidou, Yiu Tak Leung, Barry G. Garchow, Roberto Caricchio, Robert A. Eisenberg, Susanna Obad, Sakari Kauppinen, Andreas Petri, Oscar Bartulos Encinas
Publikováno v:
EMBO Molecular Medicine
Garchow, B G, Encinas, O B, Leung, Y T, Tsao, P Y, Eisenberg, R A, Caricchio, R, Obad, S, Petri, A, Kauppinen, S & Kiriakidou, M 2011, ' Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice ', E M B O Molecular Medicine, bind 3, nr. 10, s. 605-616 . https://doi.org/10.1002/emmm.201100171
Garchow, B G, Encinas, O B, Leung, Y T, Tsao, P Y, Eisenberg, R A, Caricchio, R, Obad, S, Petri, A, Kauppinen, S & Kiriakidou, M 2011, ' Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice ', E M B O Molecular Medicine, bind 3, nr. 10, s. 605-616 . https://doi.org/10.1002/emmm.201100171
MicroRNAs (miRNAs) have been implicated in B cell lineage commitment, regulation of T cell differentiation, TCR signalling, regulation of IFN signalling, and numerous other immunological processes. However, their function in autoimmunity, and specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfbef7551ca39fe95c80cd804911e2d
https://pubmed.ncbi.nlm.nih.gov/21882343
https://pubmed.ncbi.nlm.nih.gov/21882343
Publikováno v:
BMC Molecular Biology
BMC Molecular Biology, Vol 12, Iss 1, p 19 (2011)
BMC Molecular Biology, Vol 12, Iss 1, p 19 (2011)
Background Argonaute, the core component of the RNA induced silencing complex (RISC), binds to mature miRNAs and regulates gene expression at transcriptional or post-transcriptional level. We recently reported that Argonaute 2 (Ago2) also assembles i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e604c813634014abdb21b405072286e
https://doi.org/10.1186/1471-2199-12-19
https://doi.org/10.1186/1471-2199-12-19
Autor:
Barry G. Garchow, Bakul Dhagat Mehta, Sonali P. Jog, Pushpalatha P.N. Murthy, Jodi M. Monosso
Publikováno v:
Protein expression and purification. 46(2)
Phytases catalyze the hydrolysis of phytic acid ( myo -inositol hexakisphosphate), the most abundant inositol phosphate in cells. Phytases are of great commercial importance because their use as food and animal feed supplement has been approved by ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa667bc11f902bf63705e649bd67235e
https://pubmed.ncbi.nlm.nih.gov/16198125
https://pubmed.ncbi.nlm.nih.gov/16198125