Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Barry D. Moore"'
Autor:
Yolanda Corripio-Miyar, Clair Lyle MacLeod, Iris Mair, Richard J. Mellanby, Barry D. Moore, Tom N. McNeilly
Publikováno v:
Vaccines, Vol 11, Iss 7, p 1229 (2023)
Successful vaccines require adjuvants able to activate the innate immune system, eliciting antigen-specific immune responses and B-cell-mediated antibody production. However, unwanted secondary effects and the lack of effectiveness of traditional adj
Externí odkaz:
https://doaj.org/article/da6718edaf5e47c8b472a5cac84095e1
Autor:
Barry D. Moore, Clair Macleod, Lisa Henning, Robert Krile, Ying-Liang Chou, Thomas R. Laws, Wendy A. Butcher, Kristoffer M. Moore, Nicola J. Walker, Ethel Diane Williamson, Darrell R. Galloway
Publikováno v:
Vaccines, Vol 10, Iss 2, p 145 (2022)
Background: The need for an updated plague vaccine is highlighted by outbreaks in endemic regions together with the pandemic potential of this disease. There is no easily available, approved vaccine. Methods: Here we have used a murine model of pneum
Externí odkaz:
https://doaj.org/article/d5730a07d23a4f4b930a89a083d222fe
Autor:
Barry D. Moore, Clair Macleod, Lisa Henning, Robert Krile, Ying-Liang Chou, Thomas R. Laws, Wendy A. Butcher, Kristoffer M. Moore, Nicola J. Walker, Ethel Diane Williamson, Darrell R. Galloway
Publikováno v:
Vaccines; Volume 10; Issue 2; Pages: 145
Background: The need for an updated plague vaccine is highlighted by outbreaks in endemic regions together with the pandemic potential of this disease. There is no easily available, approved vaccine. Methods: Here we have used a murine model of pneum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d0034bf3cd60cad88a7cc1292fcb43
https://pubmed.ncbi.nlm.nih.gov/35214604
https://pubmed.ncbi.nlm.nih.gov/35214604
Autor:
L.C.D. Gibson, Barry D. Moore, Neil Almond, R. Mahood, Michael Bogus, Lyn M. O’Brien, Ruth Harvey, M. Bayliss, Ethel Diane Williamson, Mark S. Lever, Simon A. Weller, R.R.C. New, C. Macleod, Sophie J. Smither, W. Butcher
Publikováno v:
Vaccine
Highlights • A novel dual route vaccination using the MERS-CoV RBD sub-unit has been developed. • Murine antisera induced to the RBD protein , were neutralising in vitro. • MERS-CoV susceptibility was induced in naïve mice with Ad5hDPP4. • P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874ee985c3cf010de2dc2714e16c34f3
https://doi.org/10.1016/j.vaccine.2019.05.074
https://doi.org/10.1016/j.vaccine.2019.05.074
Autor:
Michael Bogus, J. Steward, C. Macleod, Roger New, Ethel Diane Williamson, Barry D. Moore, W. Butcher, R. Mahood, M. Bayliss
Publikováno v:
Vaccine. 36(34)
Here, we report a dual-route vaccination approach for plague, able to induce a rapid response involving systemic and mucosal immunity, whilst also providing ease of use in those resource-poor settings most vulnerable to disease outbreaks. This novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b58909d733b9667daff2965d24e6e6
https://pubmed.ncbi.nlm.nih.gov/30017148
https://pubmed.ncbi.nlm.nih.gov/30017148
Autor:
Jan Sefcik, Nadeem Javid, Georgina Zimbitas, Anna Jawor-Baczynska, John Parkinson, Barry D. Moore, Maria J. Vesga
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 579:123633
In this work DLS, NTA, SAXS and NMR were used to investigate populations, size distributions and structure of clusters in undersaturated aqueous solutions of glycine. Molecular and colloidal scale (mesoscale) clusters with radii around 0.3-0.5 nm and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4231c895f10a0c3fdbcc486665cbea1b
https://doi.org/10.1016/j.colsurfa.2019.123633
https://doi.org/10.1016/j.colsurfa.2019.123633
Publikováno v:
Crystal Growth & Design. 13:470-478
Recent theoretical and experimental studies have proposed a two-step mechanism for crystal formation in which crystal nucleation is preceded by formation of disordered molecular assemblies. Here, we investigated whether similar intermediates might al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c99e278d194a97979a56ec1d64f0f98
https://doi.org/10.1021/cg300150u
https://doi.org/10.1021/cg300150u
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 82:475-484
Insoluble aggregation or precipitation is one of the most common degradation pathways observed for biotherapeutics; despite this, the structural mechanisms by which this occurs remain poorly understood due to difficulties associated with biophysical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f0cf172482eb4abcea6279fb925b4a
https://doi.org/10.1016/j.ejpb.2012.05.019
https://doi.org/10.1016/j.ejpb.2012.05.019
Autor:
Munerah Alfadhel, Christopher F. van der Walle, Steven Ford, Parag Mane, Eva Alvarez-Gonzalez, Barry D. Moore
Publikováno v:
Biotechnology Progress. 28:540-548
We present an alternative bioprocess for bacteriophages involving room temperature coprecipitation of an aqueous mixture of phage (Siphoviridae) and a crystallizable carrier (glutamine or glycine) in excess of water miscible organic solvent (isopropa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a90a83381b675a64d9e66b69ad8f0fc
https://doi.org/10.1002/btpr.740
https://doi.org/10.1002/btpr.740
Autor:
Karen Faulds, Julie Redden, Duncan Graham, Kirsty F. Gibson, Barry D. Moore, Robert J. Stokes, Andrew Ingram
Publikováno v:
Analytical Chemistry. 79:8578-8583
A series of surface-enhanced resonance Raman scattering (SERRS) based probes for the detection of lipase activity are reported. A number of novel SERRS-active 8-hydroxylquinolinyl azo dyes have been prepared and via synthetic esterification or subseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8945142efc4474f1f6896bd43e5c105
https://doi.org/10.1021/ac071409a
https://doi.org/10.1021/ac071409a