Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Barry D. Gehm"'
Autor:
Anait S. Levenson, V. Craig Jordan, J. Larry Jameson, Hong Liu, Bethany M. Amundsen, Eun Jig Lee, Barry D. Gehm, Mark Cushman
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 88:223-234
Resveratrol, a hydroxystilbene found in grapes and wine, has previously been shown to be a non-flavonoid phytoestrogen, and to act as an estrogen receptor (ER) superagonist in MCF-7 cells transiently transfected with estrogen-responsive reporter cons
Autor:
V. Craig Jordan, Jun Horiguchi, Barry D. Gehm, Sandra Timm Pearce, Laura A. Simons, James E. Ward, J. Larry Jameson, Anait S. Levenson
Publikováno v:
International Journal of Cancer. 104:587-596
Resveratrol (Res) is a phytoestrogen found in grapes and present in red wine. Res has been shown to function as an estrogen receptor (ER) agonist, but it remains unclear whether it may also exert antagonist activity. Our aim was to study the effects
Autor:
Monika Jakacka, Pei Yu Chien, Fred Martinson, Barry D. Gehm, W. Rachel Duan, J. Larry Jameson, Eun Jig Lee
Publikováno v:
Molecular Medicine. 7:773-782
BACKGROUND: Estrogen receptors (ER) are expressed in about two thirds of human breast cancer, and are an important pharmacological target for treatment of these tumors. Dominant negative forms of the ER have been suggested as an alternative method to
Publikováno v:
Endocrinology. 142:3756-3763
The ER plays an important role in the proliferation and differentiation of lactotrope tumor cells. GH(4) cells were infected with adenoviral vectors (AdL540Q and Ad1-536) to investigate the ability of dominant negative ER mutants to affect the regula
Publikováno v:
Journal of Biological Chemistry. 276:13615-13621
In the classical signaling pathway, the estrogen receptor (ER) binds directly to estrogen response elements (EREs) to regulate gene transcription. To test the hypothesis that the nonclassical pathway involves ER interactions with other proteins rathe
Autor:
Barry D. Gehm, Sylvie Laquerre, Richard M. Pinke, David G. McConnell, David J. Pepperl, Donna A. Schultz, James G. Chafouleas
Publikováno v:
Biochemistry. 30:11302-11306
Calmodulin antagonists stimulated phosphatidylinositol-4,5-bisphosphate phospholipase C in soluble and particulate fractions of bovine rod outer segments. Antagonists tested include trifluoperazine, melittin, calmidazolium, compound 48/80, W-13 [N-(4
Publikováno v:
Molecular Endocrinology. 5:1467-1476
The insulin-degrading enzyme (IDE) is an evolutionarily conserved enzyme that has been implicated in cellular insulin degradation, but its site of action and importance in regulating insulin degradation have not been clearly established. We addressed
Autor:
Barry D. Gehm, Anait S. Levenson
Publikováno v:
Oxidative Stress and Disease ISBN: 9780849333712
Resveratrol in Health and Disease
Resveratrol in Health and Disease ISBN: 9780429118746
Resveratrol in Health and Disease
Resveratrol in Health and Disease ISBN: 9780429118746
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e43a92c6b2b3bc9e4be65188b44db3
https://doi.org/10.1201/9781420026474.ch17
https://doi.org/10.1201/9781420026474.ch17
Publikováno v:
Molecular and cellular endocrinology. 159(1-2)
Epidermal growth factor (EGF) mimics the effects of estrogen on some cells, suggesting that it may activate the estrogen receptor (ER). We examined the ability of EGF to increase expression of several different estrogen-responsive luciferase reporter
The phytochemical resveratrol, which is found in grapes and wine, has been reported to have a variety of anti-inflammatory, anti-platelet, and anti-carcinogenic effects. Based on its structural similarity to diethylstilbestrol, a synthetic estrogen,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dec36739695c8cfedaadb3df1848548
https://europepmc.org/articles/PMC28446/
https://europepmc.org/articles/PMC28446/