Zobrazeno 1 - 10 of 242 pro vyhledávání: '"Barry Bresnihan"'
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Akademický článek
Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease.
Autor: Ceara E Walsh, Elizabeth J Ryan, Cliona O'Farrelly, Lucy Golden-Mason, Oliver FitzGerald, Douglas J Veale, Barry Bresnihan, Ursula Fearon
Publikováno v: PLoS ONE, Vol 6, Iss 11, p e27182 (2011)
ObjectiveTNF inhibitors (TNFi) have revolutionised the treatment of rheumatoid arthritis (RA). Natural killer (NK) cells and Natural Killer Cell Receptor+ T (NKT) cells comprise important effector lymphocytes whose activity is tightly regulated throu
Externí odkaz: https://doaj.org/article/26294b28a0c041b9b489ec5455461129
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2
Perceptions of the Cause, Impact and Management of Persistent Fatigue in Patients with Rheumatoid Arthritis Following Tumour Necrosing Factor Inhibition Therapy
Autor: Douglas J. Veale, Oliver FitzGerald, Anders Ringnér, Gabrielle McKee, Barry Bresnihan, Patricia Minnock
Publikováno v: Musculoskeletal Care. 15:23-35
Introduction: Fatigue is a major symptom of rheumatoid arthritis (RA), the most common chronic inflammatory joint disease. The present study explored patients' experiences of RA fatigue to elucidat ...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70258b05dcda16216a94b75987e3811a
https://doi.org/10.1002/msc.1136
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3
Perceptions of the Cause, Impact and Management of Persistent Fatigue in Patients with Rheumatoid Arthritis Following Tumour Necrosing Factor Inhibition Therapy
Autor: Patricia, Minnock, Anders, Ringnér, Barry, Bresnihan, Douglas, Veale, Oliver, FitzGerald, Gabrielle, McKee
Publikováno v: Musculoskeletal care. 15(1)
Fatigue is a major symptom of rheumatoid arthritis (RA), the most common chronic inflammatory joint disease. The present study explored patients' experiences of RA fatigue to elucidate unique elements and management strategies.This single site study
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4b0b044f72bd11c16d5aae3256bb5c09
https://pubmed.ncbi.nlm.nih.gov/26871999
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4
The Impact of a Revised EQ-5D Population Scoring on Preference-Based Utility Scores in an Inflammatory Arthritis Cohort
Autor: Roisin Adams, Barry Bresnihan, Michael J. Barry, Cathal Walsh, Douglas J. Veale, Oliver FitzGerald, Benjamin M. Craig
Publikováno v: Value in Health. 14(6):921-927
Background and Objective It is well established that there are problems with the EQ-5D. This is due to the original scoring methods used and how negative time trade-off (TTO) values were treated. A revised scoring method has been published. This arti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c6e233979f0398b42f92d2371bbc57
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5
Acute Serum Amyloid A Induces Migration, Angiogenesis, and Inflammation in Synovial Cells In Vitro and in a Human Rheumatoid Arthritis/SCID Mouse Chimera Model
Autor: Ursula Fearon, Mary Connolly, Ronan H Mullan, Mark Blades, Paola Maderna, Douglas J. Veale, Barry Bresnihan, Catherine Godson, Alessandra Marrelli, J. McCormick, Costantino Pitzalis, Oliver FitzGerald
Publikováno v: The Journal of Immunology. 184:6427-6437
Serum amyloid A (A-SAA), an acute-phase protein with cytokine-like properties, is expressed at sites of inflammation. This study investigated the effects of A-SAA on chemokine-regulated migration and angiogenesis using rheumatoid arthritis (RA) cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e9aa6a1ab03b91cd6d885eea126ff0
https://doi.org/10.4049/jimmunol.0902941
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6
Understanding the Relationship between the EQ-5D, SF-6D, HAQ and Disease Activity in Inflammatory Arthritis
Autor: Michael J. Barry, Douglas J. Veale, Barry Bresnihan, Roisin Adams, Cathal Walsh, Oliver FitzGerald
Publikováno v: PharmacoEconomics. 28:477-487
Background: The growth of economic analyses and in particular cost-utility analyses (CUA), which use the QALY as a measure of outcome, has heightened the interest in the methodologies used to calculate the QALY. The EQ-5D has produced quite different
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc5caa36405737d1ccc94ca41c40964
https://doi.org/10.2165/11533010-000000000-00000
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7
Synovial tissue hypoxia and inflammation in vivo
Autor: Cormac T. Taylor, Monika Biniecka, Donal J. Buggy, Jacintha O'Sullivan, Ursula Fearon, Douglas J. Veale, J. McCormick, Oliver FitzGerald, Aisling Kennedy, Chin Teck Ng, Barry Bresnihan
Publikováno v: Annals of the Rheumatic Diseases
Hypoxia is a microenvironmental feature in the inflamed joint, which promotes survival advantage for cells. The aim of this study was to examine the relationship of partial oxygen pressure in the synovial tissue (tPO(2)) in patients with inflammatory
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7252e94d1ada9695971d1273e5bac45
https://doi.org/10.1136/ard.2009.119776
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A Role for the High-Density Lipoprotein Receptor SR-B1 in Synovial Inflammation via Serum Amyloid-A
Autor: Barry Bresnihan, Mary Connolly, Ursula Fearon, J. McCormick, Douglas J. Veale, Ronan H Mullan
Publikováno v: The American Journal of Pathology. 176:1999-2008
Acute phase apoprotein Serum Amyloid A (A-SAA), which is strongly expressed in rheumatoid arthritis synovial membrane (RA SM), induces angiogenesis, adhesion molecule expression, and matrix metalloproteinase production through the G-coupled receptor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53949d8e9561e7a251c8fc639a0b9a8
https://doi.org/10.2353/ajpath.2010.090014
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9
A qualitative study of work participation in early rheumatoid arthritis
Autor: Douglas J. Veale, Yvonne Codd, Tadhg Stapleton, Oliver FitzGerald, Barry Bresnihan
Publikováno v: International Journal of Therapy and Rehabilitation. 17:24-33
Aims This article details a qualitative study aiming to explore the impact of rheumatoid arthritis (RA) on participation in paid work during the first two years after diagnosis. Methods In-depth semi-structured interviews using the Model of Human Occ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22e380c96624d4a3cabc88ea25fa9e19
https://doi.org/10.12968/ijtr.2010.17.1.45990
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10
CCR5 blockade in rheumatoid arthritis: a randomised, double-blind, placebo-controlled clinical trial
Autor: Arno W R, van Kuijk, Clarissa E, Vergunst, Danielle M, Gerlag, Barry, Bresnihan, Juan J, Gomez-Reino, Regine, Rouzier, Patrick C, Verschueren, Christiaan, van der Leij, Christiaan, van de Leij, Mario, Maas, Maarten C, Kraan, Paul P, Tak
Publikováno v: Annals of the rheumatic diseases, 69(11), 2013-2016. BMJ Publishing Group
Annals of the Rheumatic Diseases, 69(11), 2013-2016. BMJ Publishing Group
ObjectiveC-C chemokine receptor type 5 (CCR5), a chemokine receptor expressed on T cells and macrophages, and its ligands are found in inflamed synovial tissue (ST) of patients with rheumatoid arthritis (RA). The rationale for testing CCR5 blockade i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f659fb6371d2bdebd784751e24d679
https://doi.org/10.1136/ard.2010.131235
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