Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Barry, Kesner"'
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100819- (2021)
Summary: The isolation of protein-RNA complexes in the “denaturing cross-linked RNA immunoprecipitation” (dCLIP) protocol is based on biotin-tagging proteins of interest, UV cross-linking RNA to protein in vivo, RNase protection assay, and isolat
Externí odkaz:
https://doaj.org/article/b65798577737407a813672ec527aad2f
Autor:
Rodrigo Aguilar, Kerrie B. Spencer, Barry Kesner, Noreen F. Rizvi, Maulik D. Badmalia, Tyler Mrozowich, Jonathan D. Mortison, Carlos Rivera, Graham F. Smith, Julja Burchard, Peter J. Dandliker, Trushar R. Patel, Elliott B. Nickbarg, Jeannie T. Lee
Publikováno v:
Nature. 604:160-166
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8a3cf190dc85ff39d8166a46f4b293
https://doi.org/10.1038/s41586-022-04537-z
https://doi.org/10.1038/s41586-022-04537-z
Autor:
Eric Aeby, Roy Blum, Barry Kesner, Attila Szanto, Jean-Michel Garant, Jeannie T. Lee, Michael A. Rosenberg
Publikováno v:
Nature structural & molecular biology
Although polycomb repressive complex 2 (PRC2) is now recognized as an RNA-binding complex, the full range of binding motifs and why PRC2-RNA complexes often associate with active genes have not been elucidated. Here, we identify high-affinity RNA mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ba02c3fde03b7fca03b34667a6d0e0
https://doi.org/10.1038/s41594-020-00535-9
https://doi.org/10.1038/s41594-020-00535-9
Autor:
Barry Kesner, Hyun Jung Oh, Rodrigo Aguilar, Andrea J. Kriz, Hsueh-Ping Chu, Jeannie T. Lee, Hun-Goo Lee
Publikováno v:
Cell. 184(25)
Summary Chromosome loops shift dynamically during development, homeostasis, and disease. CCCTC-binding factor (CTCF) is known to anchor loops and construct 3D genomes, but how anchor sites are selected is not yet understood. Here, we unveil Jpx RNA a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8855e2533c81eebaa307a1dab734c9
https://pubmed.ncbi.nlm.nih.gov/35027738
https://pubmed.ncbi.nlm.nih.gov/35027738
Autor:
Jeannie T. Lee, Barry Kesner, Rodrigo Aguilar, Katalin Kis-Toth, Brian C. Del Rosario, Catherine Cifuentes-Rojas, Danni Wang, Attila Szanto, Roy Blum
Publikováno v:
Genes Dev
G9a is a histone methyltransferase responsible for the dimethylation of histone H3 at lysine 9 (H3K9me2). G9a plays key roles in transcriptional silencing of developmentally regulated genes, but its role in X-chromosome inactivation (XCI) has been un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f075da1af4f3359dcc7718751efa7f
https://europepmc.org/articles/PMC8247598/
https://europepmc.org/articles/PMC8247598/
Autor:
Barry Kesner, John E. Froberg, Hyun Jung Oh, Fei Ji, Hsueh-Ping Chu, Ruslan I. Sadreyev, Stefan F. Pinter, Jeannie T. Lee
Publikováno v:
Nature structural & molecular biology
In mammals, homologous chromosomes rarely pair outside meiosis. One exception is the X chromosome, which transiently pairs during X-chromosome inactivation (XCI). How two chromosomes find each other in 3D space is not known. Here, we reveal a require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe498b2ddd5789d868f0f7431b3a9cb2
https://doi.org/10.1038/nsmb.3432
https://doi.org/10.1038/nsmb.3432
Autor:
Rodrigo, Aguilar, Kerrie B, Spencer, Barry, Kesner, Noreen F, Rizvi, Maulik D, Badmalia, Tyler, Mrozowich, Jonathan D, Mortison, Carlos, Rivera, Graham F, Smith, Julja, Burchard, Peter J, Dandliker, Trushar R, Patel, Elliott B, Nickbarg, Jeannie T, Lee
Publikováno v:
Nature. 604(7904)
Although more than 98% of the human genome is non-coding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0103cca26f0fb1546a3db5ada453839
https://pubmed.ncbi.nlm.nih.gov/35864086
https://pubmed.ncbi.nlm.nih.gov/35864086
Autor:
Catherine Cifuentes-Rojas, David Colognori, Jennifer A. Erwin, Jee Young An, Stefan F. Pinter, Barry Kesner, Yesu Jeon, Johnny T. Kung, Attila Szanto, Jeannie T. Lee, Brian C. Del Rosario, Janice Y. Ahn
Publikováno v:
Molecular Cell. 57(2):361-375
CTCF is a master regulator that plays important roles in genome architecture and gene expression. How CTCF is recruited in a locus-specific manner is not fully understood. Evidence from epigenetic processes, such as X-chromosome inactivation (XCI), i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3291ac7889ac99c4de94a554753cb6
Autor:
Chunyao Wei, Barry Kesner, Myriam Boukhali, Jeannie T. Lee, Hun-Goo Lee, Hyun Jung Oh, Eric Aeby, Catherine Cifuentes-Rojas, Wilhelm Haas, Hsueh-Ping Chu
Through an integration of genomic and proteomic approaches to advance understanding of long noncoding RNAs, we investigate the function of the telomeric transcript, TERRA. By identifying thousands of TERRA target sites in the mouse genome, we demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60560e62fa69187d63c95e5a95fdac9d
https://europepmc.org/articles/PMC5552367/
https://europepmc.org/articles/PMC5552367/
Publikováno v:
Cell systems. 5(4)
Summary Interaction networks between chromatin complexes and long noncoding RNAs have become a recurrent theme in epigenetic regulation. However, technical limitations have precluded identification of RNA binding motifs for chromatin-associated prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf1a3798f34cdfd004f993a9f1f1ec8
https://pubmed.ncbi.nlm.nih.gov/29073369
https://pubmed.ncbi.nlm.nih.gov/29073369