Zobrazeno 1 - 10
of 408
pro vyhledávání: '"Barry, Honig"'
Autor:
George Rosenberger, Wenxue Li, Mikko Turunen, Jing He, Prem S. Subramaniam, Sergey Pampou, Aaron T. Griffin, Charles Karan, Patrick Kerwin, Diana Murray, Barry Honig, Yansheng Liu, Andrea Califano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-27 (2024)
Abstract Aberrant signaling pathway activity is a hallmark of tumorigenesis and progression, which has guided targeted inhibitor design for over 30 years. Yet, adaptive resistance mechanisms, induced by rapid, context-specific signaling network rewir
Externí odkaz:
https://doaj.org/article/858e3837977347e38a966598bebfacfc
Autor:
Shuwa Xu, Alina P. Sergeeva, Phinikoula S. Katsamba, Seetha Mannepalli, Fabiana Bahna, Jude Bimela, S. Lawrence Zipursky, Lawrence Shapiro, Barry Honig, Kai Zinn
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110618- (2022)
Summary: Neurons in the developing brain express many different cell adhesion molecules (CAMs) on their surfaces. CAM-binding affinities can vary by more than 200-fold, but the significance of these variations is unknown. Interactions between the imm
Externí odkaz:
https://doaj.org/article/f89dc971c1d84cf2a7121d9388e742ec
Autor:
Kerry Marie Goodman, Phinikoula S Katsamba, Rotem Rubinstein, Göran Ahlsén, Fabiana Bahna, Seetha Mannepalli, Hanbin Dan, Rosemary V Sampogna, Lawrence Shapiro, Barry Honig
Publikováno v:
eLife, Vol 11 (2022)
The stochastic expression of fewer than 60 clustered protocadherin (cPcdh) isoforms provides diverse identities to individual vertebrate neurons and a molecular basis for self-/nonself-discrimination. cPcdhs form chains mediated by alternating cis an
Externí odkaz:
https://doaj.org/article/f9b761bcb13542ab8bc955b4360d0564
Autor:
Alina P. Sergeeva, Phinikoula S. Katsamba, Filip Cosmanescu, Joshua J. Brewer, Goran Ahlsen, Seetha Mannepalli, Lawrence Shapiro, Barry Honig
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Dpr (Defective proboscis extension response) and DIP (Dpr Interacting Proteins) are immunoglobulin-like cell-cell adhesion proteins that form highly specific pairwise interactions, which control synaptic connectivity during Drosophila development. He
Externí odkaz:
https://doaj.org/article/13350acddc38455f905089b350c9c95f
Autor:
Heike Blockus, Sebi V. Rolotti, Miklos Szoboszlay, Eugénie Peze-Heidsieck, Tiffany Ming, Anna Schroeder, Nuno Apostolo, Kristel M. Vennekens, Phinikoula S. Katsamba, Fabiana Bahna, Seetha Mannepalli, Goran Ahlsen, Barry Honig, Lawrence Shapiro, Joris de Wit, Attila Losonczy, Franck Polleux
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109828- (2021)
Summary: Synaptic connectivity within adult circuits exhibits a remarkable degree of cellular and subcellular specificity. We report that the axon guidance receptor Robo2 plays a role in establishing synaptic specificity in hippocampal CA1. In vivo,
Externí odkaz:
https://doaj.org/article/ca93291c525c4a8aa7c919fed9005f37
Autor:
Zhenyi Su, Ning Kon, Jingjie Yi, Haiqing Zhao, Wanwei Zhang, Qiaosi Tang, Huan Li, Hiroki Kobayashi, Zhiming Li, Shoufu Duan, Yanqing Liu, Kenneth P. Olive, Zhiguo Zhang, Barry Honig, James J. Manfredi, Anil K. Rustgi, Wei Gu
Publikováno v:
Nature Cancer. 4:564-581
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4043dd80b186a29f1a073afe6e7e14f
https://doi.org/10.1038/s43018-023-00532-z
https://doi.org/10.1038/s43018-023-00532-z
Autor:
Indrajyoti Indra, Regina B. Troyanovsky, Lawrence Shapiro, Barry Honig, Sergey M. Troyanovsky
Publikováno v:
Cell Reports, Vol 30, Iss 8, Pp 2820-2833.e3 (2020)
Summary: We study punctate adherens junctions (pAJs) to determine how short-lived cadherin clusters and relatively stable actin bundles interact despite differences in dynamics. We show that pAJ-linked bundles consist of two distinct regions—the bu
Externí odkaz:
https://doaj.org/article/b8078a6bb4ad49d08ab7af990d9788f4
Autor:
Oliver J. Harrison, Julia Brasch, Phinikoula S. Katsamba, Goran Ahlsen, Alex J. Noble, Hanbin Dan, Rosemary V. Sampogna, Clinton S. Potter, Bridget Carragher, Barry Honig, Lawrence Shapiro
Publikováno v:
Cell Reports, Vol 30, Iss 8, Pp 2655-2671.e7 (2020)
Summary: Non-clustered δ1- and δ2-protocadherins, close relatives of clustered protocadherins, function in cell adhesion and motility and play essential roles in neural patterning. To understand the molecular interactions underlying these functions
Externí odkaz:
https://doaj.org/article/8f90b79156da49fcad93fd395bf1ec18
Autor:
Julia Brasch, Phinikoula S. Katsamba, Oliver J. Harrison, Göran Ahlsén, Regina B. Troyanovsky, Indrajyoti Indra, Anna Kaczynska, Benjamin Kaeser, Sergey Troyanovsky, Barry Honig, Lawrence Shapiro
Publikováno v:
Cell Reports, Vol 23, Iss 6, Pp 1840-1852 (2018)
Summary: Type II cadherins are cell-cell adhesion proteins critical for tissue patterning and neuronal targeting but whose molecular binding code remains poorly understood. Here, we delineate binding preferences for type II cadherin cell-adhesive reg
Externí odkaz:
https://doaj.org/article/39201ccd02124d46a1b7186f1dce4f9e
Predicting protein-protein interactions (PPI) is a challenging problem of central importance in fundamental biology. With the increasing number of available PPI prediction methods and databases, an effective evaluation model would be extremely valuab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29dfef162c0fb509bd9dd2fe1eb845fc
https://doi.org/10.1101/2023.05.25.542344
https://doi.org/10.1101/2023.05.25.542344
