Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Barry, Ganetzky"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 3109-3119 (2020)
Neuroinflammation is a major pathophysiological feature of traumatic brain injury (TBI). Early and persistent activation of innate immune response signaling pathways by primary injuries is associated with secondary cellular injuries that cause TBI ou
Externí odkaz:
https://doaj.org/article/aed6e503161e45e4ae633224d31bde57
Autor:
Joseph Blommer, Megan C. Fischer, Athena R. Olszewski, Rebeccah J. Katzenberger, Barry Ganetzky, David A. Wassarman
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
Traumatic brain injury (TBI) is a common neurological disorder whose outcomes vary widely depending on a variety of environmental factors, including diet. Using a Drosophila melanogaster TBI model that reproduces key aspects of TBI in humans, we prev
Externí odkaz:
https://doaj.org/article/94dfe11a618c423190c885356ace0f4f
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 10, Pp 3331-3346 (2018)
A screen for neuroprotective genes in Drosophila melanogaster led to the identification of a mutation that causes extreme, progressive loss of adult brain neuropil in conjunction with massive brain overgrowth. We mapped the mutation to the brain tumo
Externí odkaz:
https://doaj.org/article/9f8fbeb422814113ae72c72bf24d98df
Autor:
Ilias Kounatidis, Stanislava Chtarbanova, Yang Cao, Margaret Hayne, Dhruv Jayanth, Barry Ganetzky, Petros Ligoxygakis
Publikováno v:
Cell Reports, Vol 19, Iss 4, Pp 836-848 (2017)
During aging, innate immunity progresses to a chronically active state. However, what distinguishes those that “age well” from those developing age-related neurological conditions is unclear. We used Drosophila to explore the cost of immunity in
Externí odkaz:
https://doaj.org/article/b66a2dec93694e12bea5e7953fe613f7
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 12, Pp 4151-4166 (2016)
Outcomes of traumatic brain injury (TBI) vary because of differences in primary and secondary injuries. Primary injuries occur at the time of a traumatic event, whereas secondary injuries occur later as a result of cellular and molecular events activ
Externí odkaz:
https://doaj.org/article/98492281c7ac406ab57ca5d9b3f48384
Publikováno v:
Genetics. 223
Traumatic brain injury (TBI) outcomes vary greatly among individuals, but most of the variation remains unexplained. Using a Drosophila melanogaster TBI model and 178 genetically diverse lines from the Drosophila Genetic Reference Panel (DGRP), we in
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 7, Pp 669-677 (2015)
Children undergoing cranial radiation therapy (CRT) for pediatric central nervous system malignancies are at increased risk for neurological deficits later in life. We have developed a model of neurotoxic damage in adult Drosophila following irradiat
Externí odkaz:
https://doaj.org/article/a4d04a183fda4520997286137dea58e9
Autor:
Rebeccah J. Katzenberger, Barry Ganetzky, Edna A. Trujillo, Joshua J. Coon, Laura C Swanson, Gene H Thiede, Evgenia Shishkova, David A. Wassarman
Publikováno v:
Genetics
Traumatic brain injury (TBI) pathologies are caused by primary and secondary injuries. Primary injuries result from physical damage to the brain, and secondary injuries arise from cellular responses to primary injuries. A characteristic cellular resp
Autor:
Rebeccah J Katzenberger, Stanislava Chtarbanova, Stacey A Rimkus, Julie A Fischer, Gulpreet Kaur, Jocelyn M Seppala, Laura C Swanson, Jocelyn E Zajac, Barry Ganetzky, David A Wassarman
Publikováno v:
eLife, Vol 4 (2015)
Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Unfavorable TBI outcomes result from primary mechanical injuries to the brain and ensuing secondary non-mechanical injuries that are not limited to the brain. Our genome
Externí odkaz:
https://doaj.org/article/52f4dc41ba39414d82588d0fce68ce8a
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100637 (2014)
Expression of multiple reporter or effector transgenes in the same cell from a single construct is increasingly necessary in various experimental paradigms. The discovery of short, virus-derived peptide sequences that mediate a ribosome-skipping even
Externí odkaz:
https://doaj.org/article/2ddd2a76a1274a2c9ac329ac829e6802