Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110).

Autor: Suen, JY¹, Barry, GD¹, Lohman, RJ¹, Halili, MA¹, Cotterell, AJ¹, Le, GT¹, Fairlie, DP¹

Publikováno v: British Journal of Pharmacology. Mar2012, Vol. 165 Issue 5, p1413-1423. 11p.

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PAR2 Modulators Derived from GB88.

Autor: Yau MK; Division of Chemistry and Structural Biology, Centre for Inflammation and Disease Research and ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Liu L; Division of Chemistry and Structural Biology, Centre for Inflammation and Disease Research and ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Suen JY; Division of Chemistry and Structural Biology, Centre for Inflammation and Disease Research and ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Lim J; Division of Chemistry and Structural Biology, Centre for Inflammation and Disease Research and ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Lohman RJ; Division of Chemistry and Structural Biology, Centre for Inflammation and Disease Research and ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Jiang Y; Division of Chemistry and Structural Biology, Centre for Inflammation and Disease Research and ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Cotterell AJ; Division of Chemistry and Structural Biology, Centre for Inflammation and Disease Research and ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Barry GD; Division of Chemistry and Structural Biology, Centre for Inflammation and Disease Research and ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Mak JY; Division of Chemistry and Structural Biology, Centre for Inflammation and Disease Research and ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Vesey DA; Centre for Kidney Research, Department of Medicine, The University of Queensland, Princess Alexandra Hospital , Brisbane, Queensland 4102, Australia., Reid RC; Division of Chemistry and Structural Biology, Centre for Inflammation and Disease Research and ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Fairlie DP; Division of Chemistry and Structural Biology, Centre for Inflammation and Disease Research and ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2016 Oct 10; Vol. 7 (12), pp. 1179-1184. Date of Electronic Publication: 2016 Oct 10 (Print Publication: 2016).

Novel agonists and antagonists for human protease activated receptor 2.

Autor: Barry GD; Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Qld 4072, Australia., Suen JY, Le GT, Cotterell A, Reid RC, Fairlie DP

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2010 Oct 28; Vol. 53 (20), pp. 7428-40.

Protective effect of glucose on the anoxic myocardium of old and young mice.

Autor: Barry AC; Department of Biological Sciences, St. John's University, Jamaica, NY 11439., Barry GD, Zimmerman JA

Publikováno v: Mechanisms of ageing and development [Mech Ageing Dev] 1987 Sep 14; Vol. 40 (1), pp. 41-55.