Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Autor: Nicholas W. Wood, Chris C. A. Spencer, Konrad Koss, Heike I. Grabsch, Ananth C. Viswanathan, Simon C. Potter, Thomas L. Vaughan, Brian J. Reid, Céline Bellenguez, Kimberley Howarth, Claire Brooks, Michael Gibbons, Geoffrey Liu, David Ferry, Ian Tomlinson, Chuka U. Nwokolo, John de Caestecker, Barrie Rathbone, Francesco Lescai, Anna Rautanen, Weimin Ye, Nicholas I. Church, Nigel C. Bird, Laura J. Hardie, Peter H. Watson, Ross McManus, Peter Donnelly, David Cunningham, Peter Sasieni, Aiden Corvin, Cisca Wijmenga, Sarah Edkins, Amy Strange, Sheldon C. Cooper, Audrey Duncanson, Harvey A. Risch, Ian Sargeant, Christopher Macdonald, Pradeep Bhandari, Sarah E. Hunt, Matthew D. Rutter, John V. Reynolds, Nigel Trudgill, Rebecca Harrison, Anna H. Wu, Scott Sanders, Christopher G. Mathew, Mark S. Anderson, Raf Bisschops, Cathryn Edwards, Avazeh Tashakkori-Ghanbaria, Praful Patel, Wong Ho Chow, Anouk Van Der Winkel, Panos Deloukas, Kishor Vaidya, Manoj Nanji, Nichola L. Gellatly, Leena Peltonen, Iain A. Murray, Matthew A. Brown, Deborah Glancy, Marilie D. Gammon, Robert Plomin, Julie Hapeshi, Elia Stupka, Janusz Jankowski, Liam J. Murray, Alan G. Casson, Hugh McMurtry, Haythem Ali, Douglas A. Corley, Kausila Krishnadath, Hugh Barr, David Johnston, Derek Alderson, Ruth E Langley, Elvira Bramon, Saj Wajed, Sharon Love, Peter D. Siersema, Ernst J. Kuipers, Simon Panter, Mark R. Middleton, Ian D. Penman, Peter Isaacs, Krish Ragunath, David K. Levine, Paul Atherfold, Maikel P. Peppelenbosch, Joost P.H. Drenth, Claire Palles, Art Tucker, Stephen Attwood, Cordelia Langford, Rui Zhang, Matti Pirinen, Colin Freeman, Stephen Sawcer, Stuart MacGregor, Hugh S. Markus, S Paterson, Anna M. Nicholson, M Griffin, Nicola Burch, Colin Rodgers, Helen Winter, Anjan Dhar, Zhan Su, Emma Gray, Jantine W. P. M. van Baal, Richard C. Trembath, David Monk, Paul Mullins, Danielle Morris, Ashref Tawil, Serge Dronov, Hans Prenen, Yeng Ang, Dermot Kelleher, Gavin Band, Leslie Bernstein, Weronica E. Ek, H Smart, Luc J. W. van der Laan, Colin N. A. Palmer, Jenefer M. Blackwell, Wilbert H.M. Peters, David C. Whiteman, Tore Lind, Gosia Trynka, Helen Dallal, Paul Moayyedi, Russell D. Petty, Richard S. Gillies, Nicholas J. Shaheen, Chris Haigh, Sue Cullen, Gareth E. Davies, Julia Brown, Jean-Baptiste Cazier, Juan P. Casas, Yvonne Romero

Publikováno v: Nature Genetics, 44, 1131-6
Nature genetics
Nature Genetics, 44, 10, pp. 1131-6
Nature genetics, 44(10), 1131-+. Nature Publishing Group
Su, Z, Gay, L J, Strange, A, Palles, C, Band, G, Whiteman, D C, Lescai, F, Langford, C, Nanji, M, Edkins, S, van der Winkel, A, Levine, D, Sasieni, P, Bellenguez, C, Howarth, K, Freeman, C, Trudgill, N, Tucker, A T, Pirinen, M, Peppelenbosch, M P, van der Laan, L J W, Kuipers, E J, Drenth, J P H, Peters, W H, Reynolds, J V, Kelleher, D P, McManus, R, Grabsch, H, Prenen, H, Bisschops, R, Krishnadath, K, Siersema, P D, van Baal, J W P M, Middleton, M, Petty, R, Gillies, R, Burch, N, Bhandari, P, Paterson, S, Edwards, C, Penman, I, Vaidya, K, Ang, Y, Murray, I, Patel, P, Ye, W, Mullins, P, Wu, A H, Bird, N C, Lind, T & Esophageal Adenocarcinoma Genetics Consortium 2012, ' Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus ', Nature Genetics, vol. 44, no. 10, pp. 1131-6 . https://doi.org/10.1038/ng.2408
Nature Genetics, 44(10), 1131-+. Nature Publishing Group

Barrett's esophagus is an increasingly common disease that is strongly associated with reflux of stomach acid and usually a hiatus hernia, and it strongly predisposes to esophageal adenocarcinoma (EAC), a tumor with a very poor prognosis. We report t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8117915f712f09f81ec147e0ad2843
http://ora.ox.ac.uk/objects/uuid:89f39572-3941-4dbb-b208-14af73dbc475

Frank Edward Nichol

Autor: Waji Hassan, Barrie Rathbone

Publikováno v: BMJ. 350:h1009-h1009

Frank Edward Nichol grew up in Manchester and was a lifelong supporter of Manchester City Football Club. He studied at Liverpool University, obtaining a first class honours degree in anatomy before qualifying in medicine. He specialised in general me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a121b3d85ab3b0a9cb02a93feb3585d
https://doi.org/10.1136/bmj.h1009

Mesalazine 4 g daily given as prolonged-release granules twice daily and four times daily is at least as effective as prolonged-release tablets four times daily in patients with ulcerative colitis

Autor: Barrie Rathbone, Thomas A. Hinterleitner, Einar Oddsson, Daniel Rachmilewitz, Milan Lukas, Ralf Keller, Rémy Meier, Xavier Hébuterne, Per G. Farup, Massimo Campieri

Publikováno v: Scopus-Elsevier

Background High doses of mesalazine usually result in an inconvenient dosage schedule and reduced compliance. The goal of this trial was to compare the effects of mesalazine 4 g daily given as prolonged-release granules in packets of 1 g with that of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a76e18928cc2ffaf7cb5e9d4e21873
http://www.scopus.com/inward/record.url?eid=2-s2.0-0034893382&partnerID=MN8TOARS