Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Barrie M. Phillips"'
Publikováno v:
Journal of Pharmaceutical Sciences. 65:447-450
Rats received the equivalent of 100, 250, 500, or 700 mg/kg of 14C-aspirin orally as a suspension or as a solution of a buffered, effervescent, aspirin-containing product. Animals in each dose group were sacrificed at time intervals ranging from 0.5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed7f9d4f01bce368d4a9880c892aa94
https://doi.org/10.1002/jps.2600650337
https://doi.org/10.1002/jps.2600650337
Publikováno v:
Journal of Medicinal Chemistry. 18:509-513
A series of 34 beta-arylamidoacrylic acids was prepared and examined for antiinflammatory activity. These compounds are vinylogous carbamic acids, and several displayed activity equal to phenylbutazone in the rat pleural effusion model. Highest activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d09066232869390863c71d20604fba
https://doi.org/10.1021/jm00239a015
https://doi.org/10.1021/jm00239a015
Publikováno v:
Drug Information Journal. 12:141-152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61bd61317a39c93661fd0c46b02cc477
https://doi.org/10.1177/009286157801200304
https://doi.org/10.1177/009286157801200304
Publikováno v:
Life Sciences. 13:685-691
Quipazine (2-(1-piperazinyl)quinoline maleate), an agent with anti-tremorine and serotonin-like activity, was found to inhibit the uptake of 3 H-dopamine and 3 H-serotonin into rat striatal tissue in vitro . Quipazine was shown to be three times more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::107fe02626d219510f551e421afb76bc
https://doi.org/10.1016/0024-3205(73)90285-3
https://doi.org/10.1016/0024-3205(73)90285-3
Publikováno v:
Toxicology and Applied Pharmacology. 20:515-521
Human (radiochromate) studies of the effects of aspirin on gastrointestinal microbleeding are limited to 4 treatment periods, and since adequate evaluation of the effect of a new formulation requires the use of both positive and negative aspirin-cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749f58d51d4b320a53f4c611b1ca2801
https://doi.org/10.1016/0041-008x(71)90255-9
https://doi.org/10.1016/0041-008x(71)90255-9
Autor:
Tom S. Miya, Barrie M. Phillips
Publikováno v:
Journal of Pharmaceutical Sciences. 53:1098-1101
Prochloroperazine was shown to be distributed in the organs of the rat much like other weak organic bases. Drug absorption was retarded in repeatedly treated rats and certain tissues appeared to play a storage role. Excretion studies revealed that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d8e83a3380ec7c5ba5b8bdfb86a5ff
https://doi.org/10.1002/jps.2600530925
https://doi.org/10.1002/jps.2600530925
Autor:
Barrie M. Phillips
Publikováno v:
Toxicology and Applied Pharmacology. 24:182-189
59Fe-labeled ferrous sulfate was administered iv to 12 male dogs, and gastrointestinal microbleeding was determined by comparison of the 59Fe specific activities of 24-hr stool collections and of whole blood. During a 69-day period following injectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f541d5b2b48dafba92988e636154ae
https://doi.org/10.1016/0041-008x(73)90138-5
https://doi.org/10.1016/0041-008x(73)90138-5
Publikováno v:
Toxicology and Applied Pharmacology. 17:553-555
For 12 weeks, after a 14-day pretrial period during which three baseline intraocular pressure (IOP) determinations were made, rabbits received 0.05 ml of a pH 7.0 phosphate buffer twice daily in the conjunctival sac, or were subjected to the same phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ef3ff7aa278dde4ff7fa7875132416
https://doi.org/10.1016/0041-008x(70)90214-0
https://doi.org/10.1016/0041-008x(70)90214-0
Publikováno v:
Journal of Pharmaceutical Sciences. 54:803-805
A procedure for the determination of a mixture of secondary and tertiary amines in urine is described. The method is based on the formation of dithiocarbamic acids from secondary amines and carbon disulfide, followed by the reaction of this acid with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6acf9b5b438b8d3dc53b931370d8aa1
https://doi.org/10.1002/jps.2600540535
https://doi.org/10.1002/jps.2600540535
Autor:
Barrie M. Phillips, Tom S. Miya
Publikováno v:
Experimental Biology and Medicine. 112:706-708
SummaryInitial S35 tissue levels were higher in jaundiced than in control rats following S35-prochlorperazine administration. However, 8 hours later tissue levels were lower in jaundiced rats. After this time tissue levels decreased very slowly in ja
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac801b0f9e6ecb49afba18c42adf4268
https://doi.org/10.3181/00379727-112-28146
https://doi.org/10.3181/00379727-112-28146