Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Barrie C. Finnin"'
Publikováno v:
International Journal of Pharmaceutics. 305:90-104
Employing thermal analysis, we investigated the mechanism of action of novel enhancers and probed phospholipid (PL) versus stratum corneum lipid (SCL) liposomes as model membranes. The enhancers included octyl salicylate (OS), padimate O (PADO) and 2
Autor:
Barrie C. Finnin, Beverley J. Thomas
Publikováno v:
Drug Discovery Today. 9:697-703
Historically, developments in transdermal drug delivery have been incremental, focusing on overcoming problems associated with the barrier properties of the skin, reducing skin irritation rates and improving the aesthetics associated with passive pat
Publikováno v:
International Journal of Pharmaceutics. 271:5-10
Differential scanning calorimetry (DSC) was used to investigate the mechanism of action of a proprietary skin penetration enhancer, dodecyl-2-(N,N-dimethylamino)propionate (DDAIP) in dipalmitoylphosphatidylcholine (DPPC) liposomes. Furthermore, the e
Publikováno v:
Journal of Pharmaceutical Sciences. 88:955-958
Publikováno v:
Drug Development Research. 46:316-327
Drug delivery is a key factor contributing to the commercial and therapeutic potential of many drugs and related products. Drug delivery underpins the development of new chemical entities, and it is the driving force behind the development of many ne
Publikováno v:
Analytica Chimica Acta. 324:1-11
A study of the irreversible oxidation of l -tyrosine and a series of catecholamines has been undertaken at a microelectrode under both flow analysis and reversed-phase liquid chromatography (LC) conditions. Experimental parameters (electrode radius 5
Publikováno v:
Analytical Chemistry. 65:3252-3257
A study of the one-electron reversible ferrocene oxidation process has been made under both flow injection analysis and normal-phase chromatography conditions in a thin-layer flow cell with a rapid-scanning microelectrode-based detector. A flow rate
Publikováno v:
Journal of Electroanalytical Chemistry. 356:25-42
An explicit finite difference simulation is used to describe chronoamperometry at a disk microelectrode in a channel flow solution. All known phenomenologically important processes are represented in the simulation, including the electrode “edge ef
Publikováno v:
Pharmaceutical Research. :1144-1150
The steady-state flux (SSF) of nicotinamide from an aqueous donor phase across a model Silastic membrane did not increase proportionally with increasing donor phase concentration. The suspected self-association of the drug in aqueous solution was eva
Publikováno v:
Collection of Czechoslovak Chemical Communications. 56:192-205
A microelectrode based detector system has been developed for measurement of steady state voltammetric curves in flowing solutions. Two microprocessors operating in parallel allow the direct transfer of collected data to a floppy diskette. Long term