Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Barrett P. Eynon"'
Autor:
Georges Natsoulis, Cecelia I Pearson, Jeremy Gollub, Barrett P Eynon, Joe Ferng, Ramesh Nair, Radha Idury, May D Lee, Mark R Fielden, Richard J Brennan, Alan H Roter, Kurt Jarnagin
Publikováno v:
Molecular Systems Biology, Vol 4, Iss 1, Pp 1-12 (2008)
Abstract We have used a supervised classification approach to systematically mine a large microarray database derived from livers of compound‐treated rats. Thirty‐four distinct signatures (classifiers) for pharmacological and toxicological end po
Externí odkaz:
https://doaj.org/article/6e30909c4ba24ef580ca8d7881010182
Autor:
Kurt Jarnagin, Shane Dunlea, Georges Natsoulis, Cecelia Pearson, Fabrice Leroy, Alexander M. Tolley, Barrett P. Eynon, Gert R. G. Lanckriet, Laurent El Ghaoui, Stuart Tugendreich
Publikováno v:
Genome Research. 15:724-736
A large gene expression database has been produced that characterizes the gene expression and physiological effects of hundreds of approved and withdrawn drugs, toxicants, and biochemical standards in various organs of live rats. In order to derive u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8845ce9a985edb2916a5bcd83563e0fb
https://doi.org/10.1101/gr.2807605
https://doi.org/10.1101/gr.2807605
Autor:
Thomas S. Kilduff, Barrett P Eynon, Stephen R. Morairty, Linda Dousman, A. Apte-Deshpande, Yvonne R. Freund, Akira Terao
Publikováno v:
Journal of Neuroimmunology. 132:99-112
Using GeneChipsR, basal and lipopolysaccharide (LPS)-induced gene expression was examined in the hippocampus of 3-, 12-, 18- and 24-month-old male C57BL/6 mice to identify genes whose altered expression could influence hippocampal function in advance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4b03d9068dc7d746659ab3f7dc15d8
https://doi.org/10.1016/s0165-5728(02)00317-x
https://doi.org/10.1016/s0165-5728(02)00317-x
Autor:
Janice W. Yager, Mark K. Shigenaga, Robert A. Jacob, Beverly Peters, Barrett P. Eynon, Bruce N. Ames, Ronald H. Jensen, Richard G. Langlois, Balz Frei, Carol M. Wehr, Robert A. Hiatt, James T. MacGregor, James D. Tucker
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 377:125-135
The 'spontaneous' frequency of genetic damage (normal background) and the possible relationship of this damage to nutritional variables in humans were investigated in 22 subjects using several indices of genetic damage. The subjects were chosen, out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228b27325de338b3c66546bab4332515
https://doi.org/10.1016/s0027-5107(97)00070-5
https://doi.org/10.1016/s0027-5107(97)00070-5
Autor:
Jeremy Gollub, Ramesh V. Nair, Radha Idury, Kurt Jarnagin, Cecelia Pearson, Barrett P. Eynon, Mark R. Fielden, Georges Natsoulis, May D Lee, Alan H. Roter, Richard J. Brennan, Joe Ferng
Publikováno v:
Molecular Systems Biology
We have used a supervised classification approach to systematically mine a large microarray database derived from livers of compound-treated rats. Thirty-four distinct signatures (classifiers) for pharmacological and toxicological end points can be i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4522fccc5e66683346fed557719b0b
https://doi.org/10.1038/msb.2008.9
https://doi.org/10.1038/msb.2008.9
Autor:
Deborah A. Banas, Kyle L. Kolaja, Georges Natsoulis, Kurt Jarnagin, Barrett P. Eynon, Mark R. Fielden
Publikováno v:
Toxicologic pathology. 33(6)
One application of genomics in drug safety assessment is the identification of biomarkers to predict compound toxicity before it is detected using traditional approaches, such as histopathology. However, many genomic approaches have failed to demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c857c44b52900977edd8cd8a14a09ec0
https://pubmed.ncbi.nlm.nih.gov/16239200
https://pubmed.ncbi.nlm.nih.gov/16239200
Autor:
Mark R. Fielden, James M. Minor, Radha Idury, Simone M. Nicholson, Jian Yang, Leslie J. Browne, Alan H. Roter, Barrett P. Eynon, Kyle L. Kolaja, Naiomi C. Breckenridge, Ramesh V. Nair, Peter Nguyen, Siqi Tan, May D Lee, Brigitte Ganter, Gwo-Jen Day, Lindsay Brady, Shane Dunlea, Christopher McSorley, Susan Y. Fujimoto, Hang Pham, Dongxu Sun, Susanne Baumhueter, L. Mike Furness, Silke Thode, Alexander M. Tolley, Zhiming Zhou, Cecelia Pearson, Georges Natsoulis, Stuart Tugendreich, Christopher Hu, Kurt Jarnagin, Keith A. Bostian, John T. Calvin, Joe Ferng, Michael S.B. Judo, Li Gong, Eser Ayanoglu, Antoaneta Vladimirova
Publikováno v:
Journal of biotechnology. 119(3)
Successful drug discovery requires accurate decision making in order to advance the best candidates from initial lead identification to final approval. Chemogenomics, the use of genomic tools in pharmacology and toxicology, offers a promising enhance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a92d42878471e7309a9e3586580030
https://pubmed.ncbi.nlm.nih.gov/16005536
https://pubmed.ncbi.nlm.nih.gov/16005536
Publikováno v:
Journal of Applied Meteorology. 27:1352-1358
The influences of meteorological factors on precipitation acidity and constituent concentrations were investigated statistically using selected portions of a new archive of daily precipitation chemistry measurements for the eastern United States. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::364305e4676751aeb7861a2c6c2f2636
https://doi.org/10.1175/1520-0450(1988)027<1352:saopcm>2.0.co
https://doi.org/10.1175/1520-0450(1988)027<1352:saopcm>2.0.co
Autor:
Barrett P. Eynon, Paul Switzer
Publikováno v:
Canadian Journal of Statistics. 11:11-23
Two years of rainfall acidity data for the eastern United States were analyzed. The data consist of rainfall-event pH measurements from a nine station monitoring network. A spatio-temporal stochastic model, including deterministic components for seas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b37498cc4d04b3d35553212707518fd3
https://doi.org/10.2307/3314707
https://doi.org/10.2307/3314707
Publikováno v:
Journal of Applied Meteorology. 27:1344-1351
The relationships between acidity and the principal chemical constituents of precipitation (including sulfate, nitrate, ammonium, calcium, magnesium, sodium, and chloride) were investigated using a new archive of daily precipitation chemistry measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e5cc58e0076e09b0c9b8db2e70a3c7c
https://doi.org/10.1175/1520-0450(1988)027<1344:saopcm>2.0.co
https://doi.org/10.1175/1520-0450(1988)027<1344:saopcm>2.0.co