Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Barrett E. Rabinow"'
Autor:
Arnaud Beduneau, Zhiya Ma, Cassi B Grotepas, Alexander Kabanov, Barrett E Rabinow, Nan Gong, R Lee Mosley, Huanyu Dou, Michael D Boska, Howard E Gendelman
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4343 (2009)
We posit that the same mononuclear phagocytes (MP) that serve as target cells and vehicles for a host of microbial infections can be used to improve diagnostics and drug delivery. We also theorize that physical and biological processes such as partic
Externí odkaz:
https://doaj.org/article/73bea34189f84395921fa16729084257
Autor:
Dennis Jenke, Barrett E. Rabinow
Publikováno v:
PDA Journal of Pharmaceutical Science and Technology. 71:225-233
When drug products contact plastic manufacturing components, packaging systems, and/or delivery devices, leachables from the plastics can accumulate in the drug product, potentially affecting its key quality attributes. Given practical issues associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c8a3346ed223451d364af0896d698a
https://doi.org/10.5731/pdajpst.2016.007195
https://doi.org/10.5731/pdajpst.2016.007195
Autor:
Justin Daller, Jeffrey S. McKee, Barrett E. Rabinow, Benjamin D Brooks, Bernhard Baumgartner, Priyanka Rohatgi
Publikováno v:
Anesthesiology. 121:1184-1193
Background: Esmolol is marketed as a racemate (RS-esmolol) with hypotension being the most frequently reported adverse event. Previously, it has been shown that the S-enantiomer (S-esmolol) possesses all of the heart rate (HR) control. The authors st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f6e7070d774ee1688a04aed5d09580
https://doi.org/10.1097/aln.0000000000000408
https://doi.org/10.1097/aln.0000000000000408
Autor:
Alison Bendele, Roy Bogseth, Jerome H. Gass, Paul W. Valaitis, Sabine Graham, Audrey M. Hutchcraft, Kelly Balla, Jane Werling, Barrett E. Rabinow
Publikováno v:
Inflammation. 38:40-60
Current therapeutic treatment options for osteoarthritis entail significant safety concerns. A novel ropivacaine crystalline microsuspension for bolus intra-articular (IA) delivery was thus developed and studied in a peptidoglycan polysaccharide (PGP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bf3386ab37c65aa91216e8092d0037
https://doi.org/10.1007/s10753-014-0006-z
https://doi.org/10.1007/s10753-014-0006-z
Autor:
Lee Sarah, Yong Zhang, Lawrence Lin, Robert M. Hoffman, Jerome H. Gass, Mahesh Chaubal, Barrett E. Rabinow, Shawn F. Bairstow, M.A. Murphy, Zhijian Yang, Jane Werling, Xiaoen Wang, James P. DiOrio
Publikováno v:
Pharmaceutical Development and Technology. 19:438-453
The purpose of this work was to prepare a stable paclitaxel nanosuspension and test it for potential use as a targeted chemotherapeutic. Different particle coatings were employed to assess their impact on cellular uptake in vitro. In vivo work was th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ee195e71f5c97b1d3ef4958cd5eb54
https://doi.org/10.3109/10837450.2013.789911
https://doi.org/10.3109/10837450.2013.789911
Autor:
JoEllyn M McMillan, Barrett E. Rabinow, Sangya Singh, Ari S. Nowacek, Shantanu Balkundi, Howard E. Gendelman, Rafael Bressani, Georgette D. Kanmogne
Publikováno v:
Nanotoxicology. 5:592-605
Limitations inherent to antiretroviral therapy (ART) in its pharmacokinetic properties remain despite over 15 years of broad use. Our laboratory has pioneered a means to improve ART delivery through monocyte-macrophage carriage of nanoformulated drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4639c608f1742231602cb47b6e615c65
https://doi.org/10.3109/17435390.2010.541292
https://doi.org/10.3109/17435390.2010.541292
Publikováno v:
Journal of Medical Toxicology. 6:331-336
Previously, it was observed that a nanosuspension formulation of itraconazole was more efficacious and yet less acutely toxic in rats as compared with the conventional solution formulation, SPORANOX® (itraconazole) Injection. The present study compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a20a3cf8c95e36132fc3225a18245b4
https://doi.org/10.1007/s13181-010-0025-6
https://doi.org/10.1007/s13181-010-0025-6
Autor:
Mahesh Chaubal, JoEllyn M McMillan, Barrett E. Rabinow, Jane Werling, Howard E. Gendelman, Cassi B. Grotepas, Christopher J. Destache, Huanyu Dou, James E. Kipp
Publikováno v:
The Journal of Immunology. 183:661-669
Antiretroviral therapy (ART) shows variable blood-brain barrier penetration. This may affect the development of neurological complications of HIV infection. In attempts to attenuate viral growth for the nervous system, cell-based nanoformulations wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6c591eef49505ccdce9693fba5624e
https://doi.org/10.4049/jimmunol.0900274
https://doi.org/10.4049/jimmunol.0900274
Autor:
Andrew Brugger, James E. Kipp, Pavlos Papadopoulos, John Ning, Barrett E. Rabinow, Joseph Chung Tak Wong, Atul Khare, Mahesh Chaubal
Publikováno v:
Advanced Drug Delivery Reviews. 60:939-954
There has been growing interest in nanoparticles as an approach to formulate poorly soluble drugs. Besides enhanced dissolution rates, and thereby, improved bioavailability, nanoparticles can also provide targeting capabilities when injected intraven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331a63c088d86eb0bb2412a13d2a7576
https://doi.org/10.1016/j.addr.2007.11.008
https://doi.org/10.1016/j.addr.2007.11.008
Autor:
Mahesh Chaubal, Christopher J. Destache, Justin R. Morehead, Huanyu Dou, You Zhou, Barrett E. Rabinow, James E. Kipp, Lyudmila S. Shlyakhtenko, Jane Werling, Jeffrey D. Kingsley, Howard E. Gendelman
Publikováno v:
Virology. 358(1):148-158
The effectiveness of anti-retroviral therapies (ART) depends on its ultimate ability to clear reservoirs of continuous human immunodeficiency virus (HIV) infection. We reasoned that a principal vehicle for viral dissemination, the mononuclear phagocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c128b0f0e3ae32d7a1219fbc81424779