Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Barrett D Allen"'
Autor:
Munjal M Acharya, Janet E Baulch, Theresa A Lusardi, Barrett D Allen, Nicole N Chmielewski, Al Anoud Doud Baddour, Charles L Limoli, Detlev eBoison
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Clinical radiation therapy for the treatment of CNS cancers leads to unintended and debilitating impairments in cognition. Radiation-induced cognitive dysfunction is long lasting, however, the underlying molecular and cellular mechanisms are still no
Externí odkaz:
https://doaj.org/article/310874a9404e4a86a081affa12839646
Autor:
Ulrike Luderer, Jinhwan Lim, Laura Ortiz, Johnny D. Nguyen, Joyce H. Shin, Barrett D. Allen, Lisa S. Liao, Kelli Malott, Veronique Perraud, Lisa M. Wingen, Rebecca J. Arechavala, Bishop Bliss, David A. Herman, Michael T. Kleinman
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-21 (2022)
Abstract Background Fine particulate matter (PM2.5) exposure accelerates atherosclerosis and contains known ovotoxic chemicals. However, effects of exposure to PM2.5 on the finite ovarian follicle pool have hardly been investigated, nor have interact
Externí odkaz:
https://doaj.org/article/67ddbca47e28404e98653275fded3079
Autor:
Vipan K. Parihar, Amber Syage, Lidia Flores, Angelica Lilagan, Barrett D. Allen, Maria C. Angulo, Joseph Song, Sarah M. Smith, Rebecca J. Arechavala, Erich Giedzinski, Charles L. Limoli
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Despite advancements in the radiotherapeutic management of brain malignancies, resultant sequelae include persistent cognitive dysfunction in the majority of survivors. Defining the precise causes of normal tissue toxicity has proven challenging, but
Externí odkaz:
https://doaj.org/article/a07efe91c2714ee2a2f4fff50b9ffa26
Autor:
Barrett D. Allen, Lauren A. Apodaca, Amber R. Syage, Mineh Markarian, Al Anoud D. Baddour, Harutyun Minasyan, Leila Alikhani, Celine Lu, Brian L. West, Erich Giedzinski, Janet E. Baulch, Munjal M. Acharya
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Numerous clinical studies have established the debilitating neurocognitive side effects of chemotherapy in the treatment of breast cancer, often referred as chemobrain. We hypothesize that cognitive impairments are associated with elevated m
Externí odkaz:
https://doaj.org/article/d00ffd698093470e903ff9075628b889
Autor:
Yasaman Alaghband, Barrett D. Allen, Eniko A. Kramár, Richard Zhang, Olivia G.G. Drayson, Ning Ru, Benoit Petit, Aymeric Almeida, Ngoc-Lien Doan, Marcelo A. Wood, Janet E. Baulch, Paola Ballesteros-Zebadua, Marie-Catherine Vozenin, Charles L. Limoli
Publikováno v:
Cancer Research Communications. 3:725-737
Implementation of ultra-high dose-rate FLASH radiotherapy (FLASH-RT) is rapidly gaining traction as a unique cancer treatment modality able to dramatically minimize normal tissue toxicity while maintaining antitumor efficacy compared with standard-of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eae2291f38138db69f48e1b8a13c6648
https://doi.org/10.1158/2767-9764.crc-23-0117
https://doi.org/10.1158/2767-9764.crc-23-0117
Autor:
Peter M. Klein, Vipan K. Parihar, Gergely G. Szabo, Miklós Zöldi, Maria C. Angulo, Barrett D. Allen, Amal N. Amin, Quynh-Anh Nguyen, István Katona, Janet E. Baulch, Charles L. Limoli, Ivan Soltesz
Publikováno v:
Neurobiology of Disease, Vol 151, Iss , Pp 105252- (2021)
Galactic cosmic radiation (GCR), composed of highly energetic and fully ionized atomic nuclei, produces diverse deleterious effects on the body. In researching the neurological risks of GCR exposures, including during human spaceflight, various groun
Externí odkaz:
https://doaj.org/article/a66003fda2bc4ad48eb746cea77b12ee
Autor:
Vipan K. Parihar, Maria C. Angulo, Barrett D. Allen, Amber Syage, Manal T. Usmani, Estrella Passerat de la Chapelle, Amal Nayan Amin, Lidia Flores, Xiaomeng Lin, Erich Giedzinski, Charles L. Limoli
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
The radiation fields in space define tangible risks to the health of astronauts, and significant work in rodent models has clearly shown a variety of exposure paradigms to compromise central nervous system (CNS) functionality. Despite our current kno
Externí odkaz:
https://doaj.org/article/bd23e2e99e3249fcbb6ff1195a69afd6
Autor:
Barrett D Allen, Yasaman Alaghband, Eniko A Kramár, Ning Ru, Benoit Petit, Veljko Grilj, Michael S Petronek, Casey F Pulliam, Rachel Y Kim, Ngoc-Lien Doan, Janet E Baulch, Marcelo A Wood, Claude Bailat, Douglas R Spitz, Marie-Catherine Vozenin, Charles L Limoli
Publikováno v:
Neuro-oncology, vol 25, iss 5
Background Ultrahigh dose-rate radiotherapy (FLASH-RT) affords improvements in the therapeutic index by minimizing normal tissue toxicities without compromising antitumor efficacy compared to conventional dose-rate radiotherapy (CONV-RT). To investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df719d4039ee2bb7f6d456c5e23cd2b1
https://escholarship.org/uc/item/56b7527q
https://escholarship.org/uc/item/56b7527q
FIGURE 3 from Uncovering the Protective Neurologic Mechanisms of Hypofractionated FLASH Radiotherapy
Autor:
Charles L. Limoli, Marie-Catherine Vozenin, Paola Ballesteros-Zebadua, Janet E. Baulch, Marcelo A. Wood, Ngoc-Lien Doan, Aymeric Almeida, Benoit Petit, Ning Ru, Olivia G.G. Drayson, Richard Zhang, Eniko A. Kramár, Barrett D. Allen, Yasaman Alaghband
Mice exposed to FLASH-RT performed similar to controls in the NOR, LDB, and FE tests. A, NOR testing. Male mice exposed to FLASH-RT performed similar to controls, while CONV-RT were unable to differentiate between the familiar and novel object. Femal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b81440a4d33e6eee49e2c69ee07151
https://doi.org/10.1158/2767-9764.22709788.v1
https://doi.org/10.1158/2767-9764.22709788.v1
FIGURE 4 from Uncovering the Protective Neurologic Mechanisms of Hypofractionated FLASH Radiotherapy
Autor:
Charles L. Limoli, Marie-Catherine Vozenin, Paola Ballesteros-Zebadua, Janet E. Baulch, Marcelo A. Wood, Ngoc-Lien Doan, Aymeric Almeida, Benoit Petit, Ning Ru, Olivia G.G. Drayson, Richard Zhang, Eniko A. Kramár, Barrett D. Allen, Yasaman Alaghband
FLASH irradiation protects against reductions in LTP after CONV irradiation, 6 months after irradiation. A, Extended novel object recognition testing, 4 months after irradiation. Female mice that exposed to FLASH-RT performed significantly better tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57341eed1346c50f6c8b2e51c963fafb
https://doi.org/10.1158/2767-9764.22709785
https://doi.org/10.1158/2767-9764.22709785