Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Barret D Pfeiffer"'
Autor:
Arnim Jenett, Gerald M. Rubin, Teri-T.B. Ngo, David Shepherd, Christine Murphy, Heather Dionne, Barret D. Pfeiffer, Amanda Cavallaro, Donald Hall, Jennifer Jeter, Nirmala Iyer, Dona Fetter, Joanna H. Hausenfluck, Hanchuan Peng, Eric T. Trautman, Robert R. Svirskas, Eugene W. Myers, Zbigniew R. Iwinski, Yoshinori Aso, Gina M. DePasquale, Adrianne Enos, Phuson Hulamm, Shing Chun Benny Lam, Hsing-Hsi Li, Todd R. Laverty, Fuhui Long, Lei Qu, Sean D. Murphy, Konrad Rokicki, Todd Safford, Kshiti Shaw, Julie H. Simpson, Allison Sowell, Susana Tae, Yang Yu, Christopher T. Zugates
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 991-1001 (2012)
We established a collection of 7,000 transgenic lines of Drosophila melanogaster. Expression of GAL4 in each line is controlled by a different, defined fragment of genomic DNA that serves as a transcriptional enhancer. We used confocal microscopy of
Externí odkaz:
https://doaj.org/article/dbd0a912927e488f9befcefdee9e79e0
Publikováno v:
eLife, Vol 4 (2015)
Drosophila central neurons arise from neuroblasts that generate neurons in a pair-wise fashion, with the two daughters providing the basis for distinct A and B hemilineage groups. 33 postembryonically-born hemilineages contribute over 90% of the neur
Externí odkaz:
https://doaj.org/article/8b02afb6fc7a4ff4ab0c21f4aec6ed78
Autor:
Marion Langen, Marta Koch, Jiekun Yan, Natalie De Geest, Maria-Luise Erfurth, Barret D Pfeiffer, Dietmar Schmucker, Yves Moreau, Bassem A Hassan
Publikováno v:
eLife, Vol 2 (2013)
Brain connectivity maps display a delicate balance between individual variation and stereotypy, suggesting the existence of dedicated mechanisms that simultaneously permit and limit individual variation. We show that during the development of the Dro
Externí odkaz:
https://doaj.org/article/258d5181d118405eb0d694e1b6c5a305
Threat displays are a universal feature of agonistic interactions. Whether threats are part of a continuum of aggressive behaviors or separately controlled remains unclear. We analyze threats in Drosophila and show they are triggered by male cues and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee0a165b1730c35d6d670385d44fd7e
https://resolver.caltech.edu/CaltechAUTHORS:20181108-124509340
https://resolver.caltech.edu/CaltechAUTHORS:20181108-124509340
Publikováno v:
Genetics. 199:683-694
Ends-out gene targeting allows seamless replacement of endogenous genes with engineered DNA fragments by homologous recombination, thus creating designer “genes” in the endogenous locus. Conventional gene targeting in Drosophila involves targetin
Autor:
Mark David Schroeder, Christopher T. Zugates, Takeshi Awasaki, Haojiang Luan, Thomas Brody, Alexander Kuzin, Ching Po Yang, Yaling Huang, Yu-Fen Huang, Tzumin Lee, Xiaotang Jing, Yisheng He, Ying Jou Lee, Chih-Fei Kao, Barret D. Pfeiffer, Ward F. Odenwald
Publikováno v:
Nature Neuroscience. 17:631-637
The Drosophila cerebrum originates from about 100 neuroblasts per hemisphere, with each neuroblast producing a characteristic set of neurons. Neurons from a neuroblast are often so diverse that many neuron types remain unexplored. We developed new ge
Autor:
Barret D. Pfeiffer, Anja B. Friedrich, Nobuhiro Yamagata, Pierre-Yves Plaçais, Hiromu Tanimoto, Igor Siwanowicz, Chang Liu, Thomas Preat, Gerald M. Rubin, Yoshinori Aso
Publikováno v:
Nature. 488:512-516
Animals approach stimuli that predict a pleasant outcome. After the paired presentation of an odour and a reward, Drosophila melanogaster can develop a conditioned approach towards that odour. Despite recent advances in understanding the neural circu
Publikováno v:
Proceedings of the National Academy of Sciences. 108:14198-14203
Site-specific recombinases have been used for two decades to manipulate the structure of animal genomes in highly predictable ways and have become major research tools. However, the small number of recombinases demonstrated to have distinct specifici
Autor:
Barret D. Pfeiffer, Christine Murphy, Arnim Jenett, Gerald M. Rubin, Teri-T B. Ngo, James W Truman, Karen L. Hibbard
Publikováno v:
Genetics. 186:735-755
A wide variety of biological experiments rely on the ability to express an exogenous gene in a transgenic animal at a defined level and in a spatially and temporally controlled pattern. We describe major improvements of the methods available for achi
Autor:
Christopher J. Mungall, Todd R. Laverty, Barret D. Pfeiffer, James T. Kadonaga, Ann S. Hammonds, Michael B. Eisen, Chris Q. Doe, Gerald M. Rubin, Arnim Jenett, Susan E. Celniker, Audra Scully, Rob Svirskas, Sima Misra, Christine Murphy, Teri T.B. Ngo, Kenneth H. Wan, Joseph W. Carlson
Publikováno v:
Proceedings of the National Academy of Sciences. 105:9715-9720
We demonstrate the feasibility of generating thousands of transgenic Drosophila melanogaster lines in which the expression of an exogenous gene is reproducibly directed to distinct small subsets of cells in the adult brain. We expect the expression p