A conserved role for Syntaxin-1 in pre- and post-commissural midline axonal guidance in fly, chick, and mouse.

Autor: Ros, Oriol^1,2, Barrecheguren, Pablo José^1,3, Cotrufo, Tiziana^1,2, Schaettin, Martina⁴, Roselló-Busquets, Cristina^1,2, Vílchez-Acosta, Alba^1,2, Hernaiz-Llorens, Marc^1,2, Martínez-Marmol, Ramón^1,2, Ulloa, Fausto^1,2, Stoeckli, Esther T.⁴ esther.stoeckli@imls.uzh.ch, Araújo, Sofia J.^3,5,6 sarbmc@ibmb.csic.es, Soriano, Eduardo^1,2,7,8 esoriano@ub.edu

Publikováno v: PLoS Genetics. 6/18/2018, Vol. 14 Issue 6, p1-28. 28p.

Blockade of the SNARE protein syntaxin 1 inhibits glioblastoma tumor growth

Autor: Ulloa, Fausto, Gonzàlez-Juncà, Alba, Meffre, Delphine, Barrecheguren, Pablo José, Martínez-Mármol, Ramón, Pazos, Irene, Olivé, Núria, Cotrufo, Tiziana, Seoane Suárez, Joan, Soriano, Eduardo, Universitat Autòmoma de Barcelona

Publikováno v: PLoS ONE
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE, Vol 10, Iss 3, p e0119707 (2015)

Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a median overall survival of 15 months from diagnosis despite of the treatment. SNARE pro- teins mediate membrane fusion events in cells and are essential fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11f6a935ac7befd8dbb838e96deb9a6
https://pubmed.ncbi.nlm.nih.gov/25803850

SNARE proteins play a role in motor axon guidance in vertebrates and invertebrates.

Autor: Barrecheguren PJ; Department of Cell Biology, Faculty of Biology, University of Barcelona, Barcelona, 08028, Spain.; Institut de Recerca Biomèdica de Barcelona (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, 08028, Spain., Ros O; Department of Cell Biology, Faculty of Biology, University of Barcelona, Barcelona, 08028, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII, Madrid, 28031, Spain., Cotrufo T; Department of Cell Biology, Faculty of Biology, University of Barcelona, Barcelona, 08028, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII, Madrid, 28031, Spain., Kunz B; Institute of Molecular Life Sciences, University of Zurich, Zurich, 8057, Switzerland., Soriano E; Department of Cell Biology, Faculty of Biology, University of Barcelona, Barcelona, 08028, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII, Madrid, 28031, Spain.; Vall d'Hebron Institute of Research (VHIR), Barcelona, 08035, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, 08010, Spain., Ulloa F; Department of Cell Biology, Faculty of Biology, University of Barcelona, Barcelona, 08028, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII, Madrid, 28031, Spain., Stoeckli ET; Institute of Molecular Life Sciences, University of Zurich, Zurich, 8057, Switzerland., Araújo SJ; Institut de Recerca Biomèdica de Barcelona (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, 08028, Spain.; Institut de Biologia Molecular de Barcelona (IBMB-CSIC), Barcelona, 08028, Spain.; Department of Genetics, Microbiology and Statistics, Faculty of Biology, University of Barcelona, Barcelona, 08028, Spain.

Publikováno v: Developmental neurobiology [Dev Neurobiol] 2017 Sep; Vol. 77 (8), pp. 963-974. Date of Electronic Publication: 2017 Feb 12.