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Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity

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Publikováno v: Scientific Reports
Scientific Reports, 2020, 10 (1), pp.6489. ⟨10.1038/s41598-020-63579-3⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.6489. ⟨10.1038/s41598-020-63579-3⟩
Scientific reports, vol. 10, no. 1, pp. 6489

Peroxisome proliferator activated receptor α (PPARα) acts as a fatty acid sensor to orchestrate the transcription of genes coding for rate-limiting enzymes required for lipid oxidation in hepatocytes. Mice only lacking Pparα in hepatocytes spontan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::49786ed8db08fd7baa1ce2888766837d
https://hdl.handle.net/10356/144951

CO-73: Rôle de PPARalpha hépatocytaire dans la réponse à la lipolyse adipocytaire et dans le diabète de type II

Autor: Montagner, A., Polizzi, A., Fouché, E., Ducheix, S., Lippi, Y., Lasserre, F., Barquissau, V., Régnier, M., Lukowicz, C., Loiseau, N., Postic, C., Langin, D., Wahli, W., Guillou, H.

Publikováno v: In Diabetes and Metabolism March 2016 42 Supplement 1:A22-A22

P189 Les agonistes de PPAR gamma et de PPAR alpha induisent la conversion d’adipocytes blancs humains en adipocytes bruns et une augmentation du métabolisme des acides gras

Autor: Beuzelin, D. ^*, Barquissau, V., Giroud, M., Béranger, G., Mairal, A., Chambard, J.-C., Pisani, D., Amri, E.-Z., Langin, D.

Publikováno v: In Diabetes and Metabolism March 2015 41 Supplement 1:A80-A81

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