Zobrazeno 1 - 10
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pro vyhledávání: '"Barnieh, Francis M."'
Autor:
Barnieh, Francis M., Morais, Goreti R., Loadman, Paul, Falconer, Robert A., El-Khamisy, Sherif
Yes
Targeted therapy remains the future of anti-cancer drug development, owing to the lack of specificity of current treatments which lead to damage in healthy normal tissues. ATR inhibitors have in recent times demonstrated promising clinical p
Targeted therapy remains the future of anti-cancer drug development, owing to the lack of specificity of current treatments which lead to damage in healthy normal tissues. ATR inhibitors have in recent times demonstrated promising clinical p
Externí odkaz:
http://hdl.handle.net/10454/19982
Yes
Despite significant preclinical promise as anticancer agents, vascular-disrupting agents have yet to fulfil their clinical potential due to systemic toxicities. ICT2588 is a tumour-selective MT1-MMP-targeted prodrug of azademethylcolchicine,
Despite significant preclinical promise as anticancer agents, vascular-disrupting agents have yet to fulfil their clinical potential due to systemic toxicities. ICT2588 is a tumour-selective MT1-MMP-targeted prodrug of azademethylcolchicine,
Externí odkaz:
http://hdl.handle.net/10454/19633
Autor:
Ortuzar, N., Karu, K., Presa, Daniela, Morais, Goreti R., Sheldrake, Helen M., Shnyder, Steven, Barnieh, Francis M., Loadman, Paul, Patterson, Laurence H., Pors, Klaus, Searcey, M.
Yes
The duocarmycins belong to a class of agent which has great potential for use in cancer therapy. Their exquisite potency means they are too toxic for systemic use, and targeted approaches are required to unlock their clinical potential. In t
The duocarmycins belong to a class of agent which has great potential for use in cancer therapy. Their exquisite potency means they are too toxic for systemic use, and targeted approaches are required to unlock their clinical potential. In t
Externí odkaz:
http://hdl.handle.net/10454/18559
Yes
The DNA damage response (DDR) is now known to play an important role in both cancer development and its treatment. Targeting proteins such as ATR (Ataxia telangiectasia mutated and Rad3-related) kinase, a major regulator of DDR, has demonstr
The DNA damage response (DDR) is now known to play an important role in both cancer development and its treatment. Targeting proteins such as ATR (Ataxia telangiectasia mutated and Rad3-related) kinase, a major regulator of DDR, has demonstr
Externí odkaz:
http://hdl.handle.net/10454/18345
Autor:
Barnieh, Francis M.
The full text will be available at the end of the embargo period: 3rd April 2025
The author's name as given on this thesis is Francis MPRAH BARNIEH. His publications use the name format Francis M. Barnieh.
The author's name as given on this thesis is Francis MPRAH BARNIEH. His publications use the name format Francis M. Barnieh.
Externí odkaz:
http://hdl.handle.net/10454/19091
Autor:
Barnieh, Francis M., Galuska, Sebastian P., Loadman, Paul M., Ward, Simon, Falconer, Robert A., El-Khamisy, Sherif F.
Publikováno v:
In iScience 17 November 2023 26(11)
Akademický článek
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Publikováno v:
In BBA - Reviews on Cancer December 2021 1876(2)
Autor:
Ortuzar, Natalia, Karu, Kersti, Presa, Daniela, Morais, Goreti R., Sheldrake, Helen M., Shnyder, Steve D., Barnieh, Francis M., Loadman, Paul M., Patterson, Laurence H., Pors, Klaus, Searcey, Mark
Publikováno v:
In Bioorganic & Medicinal Chemistry 15 June 2021 40
Akademický článek
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