Zobrazeno 1 - 10
of 2 246
pro vyhledávání: '"Barney, S"'
Autor:
Joseph P. Casazza, Amelia R. Hofstetter, Pamela J. M. Costner, LaSonji A. Holman, Cynthia S. Hendel, Alicia T. Widge, Richard L. Wu, William R. Whalen, Jennifer Cunningham, Anita Arthur, Xiaolin Wang, Abidemi Ola, Jamie Saunders, Floreliz Mendoza, Laura Novik, Maria C. Burgos Florez, Ana M. Ortega-Villa, Preeti J. Apte, Larisa Strom, Lu Wang, Marjaan Imam, Manjula Basappa, Mursal Naisan, Mike Castro, Jessica F. Trost, Sandeep R. Narpala, Hillary A. Vanderven, Galina V. Yamshchikov, Nina M. Berkowitz, Ingelise J. Gordon, Sarah H. Plummer, Diane L. Wycuff, Sandra Vazquez, Rebecca A. Gillespie, Adrian Creanga, William C. Adams, Kevin Carlton, Jason G. Gall, Adrian B. McDermott, Leonid A. Serebryannyy, Katherine V. Houser, Richard A. Koup, Barney S. Graham, Julie E. Ledgerwood, John R. Mascola, Theodore C. Pierson, Sarah F. Andrews, Masaru Kanekiyo, Lesia K. Dropulic, The VRC 323 study team
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract The relative conservation of the influenza hemagglutinin (HA) stem compared to that of the immunodominant HA head makes the HA stem an attractive target for broadly protective influenza vaccines. Here we report the first-in-human, dose-escal
Externí odkaz:
https://doaj.org/article/96bea20f4a6e46d8a78a3f7c6943f262
Autor:
Myra Happe, Amelia R. Hofstetter, Jing Wang, Galina V. Yamshchikov, LaSonji A. Holman, Laura Novik, Larisa Strom, Francis Kiweewa, Salim Wakabi, Monica Millard, Colleen F. Kelley, Sarah Kabbani, Srilatha Edupuganti, Allison Beck, Florence Kaltovich, Tamar Murray, Susanna Tsukerman, Derick Carr, Carl Ashman, Daphne A. Stanley, Aurélie Ploquin, Robert T. Bailer, Richard Schwartz, Fatim Cham, Allan Tindikahwa, Zonghui Hu, Ingelise J. Gordon, Nadine Rouphael, Katherine V. Houser, Emily E. Coates, Barney S. Graham, Richard A. Koup, John R. Mascola, Nancy J. Sullivan, Merlin L. Robb, Julie A. Ake, Kirsten E. Lyke, Mark J. Mulligan, Julie E. Ledgerwood, Hannah Kibuuka, the VRC 208 and RV 422 study team
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Ebola virus disease (EVD) is a filoviral infection caused by virus species of the Ebolavirus genus including Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV). We investigated the safety and immunogenicity of a heterologous prime-boost reg
Externí odkaz:
https://doaj.org/article/a738fdd17f884be498b68c55cc2e29cd
Autor:
Geoffrey B. Hutchinson, Olubukola M. Abiona, Cynthia T. Ziwawo, Anne P. Werner, Daniel Ellis, Yaroslav Tsybovsky, Sarah R. Leist, Charis Palandjian, Ande West, Ethan J. Fritch, Nianshuang Wang, Daniel Wrapp, Seyhan Boyoglu-Barnum, George Ueda, David Baker, Masaru Kanekiyo, Jason S. McLellan, Ralph S. Baric, Neil P. King, Barney S. Graham, Kizzmekia S. Corbett-Helaire
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Multivalent antigen display is a fast-growing area of interest toward broadly protective vaccines. Current nanoparticle-based vaccine candidates demonstrate the ability to confer antibody-mediated immunity against divergent strains of notabl
Externí odkaz:
https://doaj.org/article/977b93340ceb4969a382e3a4758201f2
Autor:
Lederhofer, Julia, Tsybovsky, Yaroslav, Nguyen, Lam, Raab, Julie E., Creanga, Adrian, Stephens, Tyler, Gillespie, Rebecca A., Syeda, Hubza Z., Fisher, Brian E., Skertic, Michelle, Yap, Christina, Schaub, Andrew J., Rawi, Reda, Kwong, Peter D., Graham, Barney S., McDermott, Adrian B., Andrews, Sarah F., King, Neil P., Kanekiyo, Masaru
Publikováno v:
In Immunity 12 March 2024 57(3):574-586
Autor:
Bonnin, Florencia A., Talarico, Laura B., Ferolla, Fausto M., Acosta, Patricio L., Phung, Emily, Kumar, Azad, Toledano, Analía, Caratozzolo, Ana, Neira, Pablo, Mascardi, Normando, Satragno, Daniela, Contrini, María M., Graham, Barney S., Ruckwardt, Tracy J., López, Eduardo L.
Publikováno v:
In Vaccine July 2024
Autor:
Cuiping Liu, Lingshu Wang, Jonah S. Merriam, Wei Shi, Eun Sung Yang, Yi Zhang, Man Chen, Wing-Pui Kong, Cheng Cheng, Yaroslav Tsybovsky, Tyler Stephens, Raffaello Verardi, Kwanyee Leung, Cody Stein, Adam S. Olia, Darcy R. Harris, Misook Choe, Baoshan Zhang, Barney S. Graham, Peter D. Kwong, Richard A. Koup, Amarendra Pegu, John R. Mascola
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract While several COVID-19 vaccines have been in use, more effective and durable vaccines are needed to combat the ongoing COVID-19 pandemic. Here, we report highly immunogenic self-assembling SARS-CoV-2 spike-HBsAg nanoparticles displaying a si
Externí odkaz:
https://doaj.org/article/9b37253d44914adeb9ec845f4062bcd4
Autor:
Daniel Ellis, Annie Dosey, Seyhan Boyoglu-Barnum, Young-Jun Park, Rebecca Gillespie, Hubza Syeda, Geoffrey B. Hutchinson, Yaroslav Tsybovsky, Michael Murphy, Deleah Pettie, Nick Matheson, Sidney Chan, George Ueda, Jorge A. Fallas, Lauren Carter, Barney S. Graham, David Veesler, Masaru Kanekiyo, Neil P. King
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113552- (2023)
Summary: Immunogen design approaches aim to control the specificity and quality of antibody responses elicited by next-generation vaccines. Here, we use computational protein design to generate a nanoparticle vaccine platform based on the receptor-bi
Externí odkaz:
https://doaj.org/article/f0b10a69337b4749a61aac233ea0c282
Autor:
Ellis, Daniel, Dosey, Annie, Boyoglu-Barnum, Seyhan, Park, Young-Jun, Gillespie, Rebecca, Syeda, Hubza, Hutchinson, Geoffrey B., Tsybovsky, Yaroslav, Murphy, Michael, Pettie, Deleah, Matheson, Nick, Chan, Sidney, Ueda, George, Fallas, Jorge A., Carter, Lauren, Graham, Barney S., Veesler, David, Kanekiyo, Masaru, King, Neil P.
Publikováno v:
In Cell Reports 26 December 2023 42(12)
Autor:
Brooke Bollman, Naveen Nunna, Kapil Bahl, Chiaowen Joyce Hsiao, Hamilton Bennett, Scott Butler, Bryant Foreman, Katherine E. Burgomaster, Maya Aleshnick, Wing-Pui Kong, Brian E. Fisher, Tracy J. Ruckwardt, Kaitlyn M. Morabito, Barney S. Graham, Kimberly A. Dowd, Theodore C. Pierson, Andrea Carfi
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Zika virus (ZIKV), an arbovirus transmitted by mosquitoes, was identified as a cause of congenital disease during a major outbreak in the Americas in 2016. Vaccine design strategies relied on limited available isolate sequence information du
Externí odkaz:
https://doaj.org/article/3c2c868a1a4e4f24a57b9b30508496ea
Autor:
Patrick O. Byrne, Brian E. Fisher, David R. Ambrozak, Elizabeth G. Blade, Yaroslav Tsybovsky, Barney S. Graham, Jason S. McLellan, Rebecca J. Loomis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Henipaviruses such as Nipah virus (NiV) cause severe encephalitis with high fatality rates in humans. NiV fusion (F) glycoprotein is a key target of the host immune response. Here, Byrne et al. isolate ten neutralizing antibodies against NiV prefusio
Externí odkaz:
https://doaj.org/article/496b231ac59e4e758d2a99f1801b371b