Tgfβ-Smad and MAPK signaling mediate scleraxis and proteoglycan expression in heart valves

Autor: Barnette, Damien N., Hulin, Alexia, Ahmed, A.S. Ishtiaq, Colige, Alain C., Azhar, Mohamad, Lincoln, Joy

Publikováno v: In Journal of Molecular and Cellular Cardiology December 2013 65:137-146

RNA-Seq Analysis to Identify Novel Roles of Scleraxis during Embryonic Mouse Heart Valve Remodeling.

Autor: Barnette, Damien N.^1,2, VandeKopple, Matthew^2,3, Wu, Yonggan⁴, Willoughby, David A.⁴, Lincoln, Joy^2,5 joy.lincoln@nationwidechildrens.org

Publikováno v: PLoS ONE. Jul2014, Vol. 9 Issue 7, p1-10. 10p.

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BRG1-SWI/SNF-dependent regulation of the Wt1 transcriptional landscape mediates epicardial activity during heart development and disease.

Autor: Vieira JM; Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK.; Molecular Medicine Unit, UCL Institute of Child Health, London WC1N 1EH, UK., Howard S; Molecular Medicine Unit, UCL Institute of Child Health, London WC1N 1EH, UK., Villa Del Campo C; Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK., Bollini S; Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK., Dubé KN; Molecular Medicine Unit, UCL Institute of Child Health, London WC1N 1EH, UK., Masters M; Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK., Barnette DN; Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK., Rohling M; Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK., Sun X; Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK., Hankins LE; Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK., Gavriouchkina D; Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK., Williams R; Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK., Metzger D; Institut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U964/CNRS UMR 7104/Université de Strasbourg, 67404 IllKirch Cedex, France., Chambon P; Institut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U964/CNRS UMR 7104/Université de Strasbourg, 67404 IllKirch Cedex, France., Sauka-Spengler T; Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK., Davies B; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Riley PR; Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK.; Molecular Medicine Unit, UCL Institute of Child Health, London WC1N 1EH, UK.

Publikováno v: Nature communications [Nat Commun] 2017 Jul 24; Vol. 8, pp. 16034. Date of Electronic Publication: 2017 Jul 24.