Zobrazeno 1 - 10
of 2 959
pro vyhledávání: '"Barnes, PJ"'
Autor:
Bradbury T, Di Tanna GL, Scaria A, Martin A, Wen FQ, Zhong NS, Zheng JP, Barnes PJ, Celli B, Berend N, Jenkins CR
Publikováno v:
International Journal of COPD, Vol Volume 17, Pp 273-282 (2022)
Thomas Bradbury,1 Gian Luca Di Tanna,1 Anish Scaria,1 Allison Martin,1 Fu-Qiang Wen,2 Nan-Shan Zhong,3 Jin-Ping Zheng,3 Peter J Barnes,4 Bartolome Celli,5 Norbert Berend,1 Christine R Jenkins1 On behalf of the TASCS Investigators1Respiratory Group, T
Externí odkaz:
https://doaj.org/article/db48cdb7d9d94db08152699791842485
Publikováno v:
International Journal of COPD, Vol Volume 13, Pp 2883-2897 (2018)
Kylie BR Belchamber, Catherine MR Thomas, Amy E Dunne, Peter J Barnes, Louise E Donnelly Airway Disease Section, National Heart and Lung Institute, Dovehouse Street, Imperial College London, London, UK Background: Inhaled corticosteroid use is associ
Externí odkaz:
https://doaj.org/article/6e07f8f5209941acaf8269fa031d08ac
Autor:
Yanagisawa, S, Papaioannou, AI, Papaporfyriou, A, Baker, JR, Vuppusetty, C, Loukides, S, Barnes, PJ, Ito, K
Publikováno v:
Chest
Background The protein deacetylase sirtuin-1 (SIRT1) is an antiaging molecule that is decreased in the lung in patients with COPD. Recently, SIRT1 was reported to be detectable in serum, but serum SIRT1 (s120S) levels have not yet been reported in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f814373005813ba7c61c58c31851cc74
http://europepmc.org/articles/PMC5540026
http://europepmc.org/articles/PMC5540026
The latest Global Initiative for Chronic Obstructive Lung Disease (GOLD) document recommends new treatment algorithms, with inhaled corticosteroids (ICS) use only in moderate-to-severely symptomatic COPD patients with repeated exacerbations, where th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::e1aa59763155cb810da0f5d84f033ae0
http://hdl.handle.net/10044/1/65336
http://hdl.handle.net/10044/1/65336
Autor:
Baker, JR, Vuppusetty, C, Colley, T, Hassibi, S, Fenwick, PS, Donnelly, LE, Ito, K, Barnes, PJ
Publikováno v:
The FASEB Journal
Diseases of accelerated aging often occur together (multimorbidity), and their prevalence is increasing, with high societal and health care costs. Chronic obstructive pulmonary disease (COPD) is one such condition, in which one half of patients exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::41ed42d06708a08fa84a2af6d433d23d
https://pubmed.ncbi.nlm.nih.gov/30156909
https://pubmed.ncbi.nlm.nih.gov/30156909
Autor:
Yanagisawa, S, Baker, JR, Vuppusetty, C, Koga, T, Colley, T, Fenwick, P, Donnelly, LE, Barnes, PJ, Ito, K, Yildirim, AÖ
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0193921 (2018)
PLoS ONE, Vol 13, Iss 3, p e0193921 (2018)
SIRT1 (silent information regulator 2 homolog 1) is a crucial cellular survival protein especially in oxidative stress environments, and has been thought to locate within the nuclei, but also known to shuttle between cytoplasm and nuclei in some cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6277f767bab6f62e6905251132153012
http://hdl.handle.net/10044/1/58025
http://hdl.handle.net/10044/1/58025
Autor:
Di Stefano, A, Sangiorgi, C, Gnemmi, I, Casolari, P, Brun, P, Ricciardolo, FL, Contoli, M, Papi, A, Maniscalco, P, Ruggeri, P, Girbino, G, Cappello, F, Pavlides, S, Guo, Y, Chung, KF, Barnes, PJ, Adcock, IM, Balbi, B, Caramori, G
BACKGROUND: The expression and localization of transforming growth factor-beta (TGF-β) pathway proteins in different compartments of the lower airways of stable COPD patients is unclear. OBJECTIVE: To determine TGF-β pathway protein expression in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::889164eeeab59c1dbefd09945b625567
http://hdl.handle.net/10044/1/55585
http://hdl.handle.net/10044/1/55585
Publikováno v:
Respiratory Research, Vol 7, Iss 1, p 111 (2006)
Abstract Small airway and vessels play a critical role in chronic airway and pulmonary vascular diseases, but their pharmacology has not been well characterised. We have studied airway and vascular responses in rat lung slices and separately in vitro
Externí odkaz:
https://doaj.org/article/97f6e7f99e644eb5b99ad8decc7aef32
Autor:
Tregoning, JS, Mallia, P, Webber, J, Gill, SK, Trujillo-Torralbo, Calderazzo, MA, Finney, L, Bakhsoliani, E, Farne, H, Singanayagam, A, Footitt, J, Hewitt, R, Kebadze, Aniscenko, J, Padmanaban, V, Molyneaux, PL, Adcock, Barnes, PJ, Ito, K, Elkin, SL, Kon, OM, Cookson, WO, MOffatt, MF, Johnston, SL
Publikováno v:
823.e6
Background Patients with chronic obstructive pulmonary disease (COPD) have increased susceptibility to respiratory tract infection, which contributes to disease progression and mortality, but mechanisms of increased susceptibility to infection remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::7cacca7b75319ee598561c063cf76b24
http://hdl.handle.net/10044/1/55776
http://hdl.handle.net/10044/1/55776
Publikováno v:
L239
L230
American Journal of Physiology-Lung Cellular and Molecular Physiology
L230
American Journal of Physiology-Lung Cellular and Molecular Physiology
The phosphatidylinositol 3-kinase (PI3K) pathway is activated in chronic obstructive pulmonary disease (COPD), but the regulatory mechanisms for this pathway are yet to be elucidated. Our aim was to determine the expression and role of phosphatase an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6186056d247d255231ede170005d3b31
http://hdl.handle.net/10044/1/48446
http://hdl.handle.net/10044/1/48446